公开(公告)号：US20240016758A1

公开(公告)日：2024-01-18

申请号：US18034480

申请日：2021-10-21

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Naoyuki UCHIDA ,  Satoshi AMANO

IPC: A61K9/70 ,  A61K31/4045 ,  A61K47/12

CPC classification number: A61K9/7084 ,  A61K31/4045 ,  A61K47/12

Abstract: A ropinirole-containing patch comprising a backing layer and an adhesive agent layer, wherein



the adhesive agent layer comprising:
at least one selected from the group consisting of ropinirole and a pharmaceutically acceptable salt thereof;
at least one sodium carboxylate selected from the group consisting of sodium pentanoate, disodium glutarate, and sodium hexanoate; and
an adhesive agent.

公开(公告)号：US20180055783A1

公开(公告)日：2018-03-01

申请号：US15565864

申请日：2016-04-15

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Naoyuki UCHIDA ,  Yasunari MICHINAKA

IPC: A61K9/70 ,  A61K31/4045 ,  A61K47/18

Abstract: The present invention provides a patch comprising a backing and an adhesive agent layer laminated on the backing, wherein the adhesive agent layer comprises ropinirole or a pharmaceutically acceptable salt thereof, an organic amine or an acid addition salt thereof, and an adhesive agent.

公开(公告)号：US20230015492A1

公开(公告)日：2023-01-19

申请号：US17779885

申请日：2020-11-20

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Naoyuki UCHIDA ,  Satoshi AMANO

IPC: A61K9/70 ,  A61K31/4045 ,  A61K47/08

Abstract: A method for improving holding power of an adhesive agent layer in a ropinirole-containing patch comprising a backing layer and the adhesive agent layer, wherein the adhesive agent layer contains at least one selected from the group consisting of ropinirole and a pharmaceutically acceptable salt thereof and an adhesive agent, the method comprising: causing the adhesive agent layer to further contain a sodium salt of carbonic acid.

公开(公告)号：US20200000737A1

公开(公告)日：2020-01-02

申请号：US16471692

申请日：2017-12-21

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Naoko FUJITA ,  Takito SHIMA ,  Kazuya KOMINAMI ,  Naoyuki UCHIDA

IPC: A61K9/70 ,  A61K31/485 ,  A61K47/14 ,  A61K47/10 ,  A61K47/34

Abstract: A patch comprising: a backing layer; and an adhesive layer, wherein the adhesive layer contains at least one drug selected from the group consisting of butorphanol and pharmaceutically acceptable salts thereof and a silicone-based adhesive base, and a mass per unit area of the adhesive layer is 30 to 90 g/m2.

公开(公告)号：US20240342125A1

公开(公告)日：2024-10-17

申请号：US18683376

申请日：2022-09-21

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Naoko FUJITA ,  Nao IWAMOTO ,  Kazuyuki HIROSE ,  Naoyuki UCHIDA

IPC: A61K31/196 ,  A61K9/70

CPC classification number: A61K31/196 ,  A61K9/7061 ,  A61K9/7069

Abstract: A method for inhibiting the generation of diclofenac indolinones in an adhesive patch is provided. This adhesive patch comprises a support body layer and an adhesive layer that is layered on the support body layer. The aforementioned method includes a step for mixing a diclofenac free acid and an adhesive base to acquire an adhesive composition, and a step for shaping the adhesive composition to obtain an adhesive patch. The content of the diclofenac free acid is 0.5-8 mass % on the basis of the total mass of the adhesive layer.

公开(公告)号：US20220362214A1

公开(公告)日：2022-11-17

申请号：US17761019

申请日：2020-09-11

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Naoyuki UCHIDA ,  Satoshi AMANO

IPC: A61K31/4045 ,  A61K9/70 ,  A61K47/14

Abstract: A ropinirole-containing patch comprising an adhesive agent layer and a backing layer, wherein the adhesive agent layer containing: at least one selected from the group consisting of ropinirole and a pharmaceutically acceptable salt thereof; a fatty acid metal salt having 7 or more carbon atoms; and an adhesive agent.