公开(公告)号：US20200306203A1

公开(公告)日：2020-10-01

申请号：US16954627

申请日：2018-12-14

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Hiroyuki ARAKI ,  Yuka TAKAGI ,  Yoko FUJIWARA ,  Hiroaki KOBAYASHI ,  Takao KUROKAWA

IPC: A61K9/70 ,  A61K31/381

Abstract: The present invention provides a rotigotine-containing patch comprising: a backing layer; and an adhesive agent layer, wherein the adhesive agent layer contains rotigotine and/or a pharmaceutically acceptable salt thereof,the adhesive agent layer further contains a styrene-based thermoplastic elastomer, a petroleum-based resin and/or a terpene-based resin, an aliphatic alcohol, and a cross-linked polyvinylpyrrolidone, andin the adhesive agent layer, a mass ratio of a content of the rotigotine and/or the pharmaceutically acceptable salt thereof in terms of rotigotine free form and a content of the cross-linked polyvinylpyrrolidone (content of the rotigotine and/or the pharmaceutically acceptable salt thereof in terms of rotigotine free form:content of the cross-linked polyvinylpyrrolidone) is 10:3 to 1:3.

公开(公告)号：US20220257528A1

公开(公告)日：2022-08-18

申请号：US17617991

申请日：2020-06-05

Applicant: Hisamitsu Pharmaceutical Co., Inc.

Inventor： Hiroyuki ARAKI ,  Yuka TAKAGI ,  Yoko FUJIWARA ,  Hiroaki KOBAYASHI ,  Takao KUROKAWA

IPC: A61K9/70 ,  A61K31/381

Abstract: The present invention provides a rotigotine-containing patch comprising: a backing layer; and an adhesive agent layer, wherein the adhesive agent layer contains rotigotine and/or a pharmaceutically acceptable salt thereof, and the adhesive agent layer further contains an alicyclic saturated hydrocarbon resin and at least one aliphatic alcohol selected from the group consisting of lauryl alcohol, octyldodecanol, oleyl alcohol, and myristyl alcohol.

公开(公告)号：US20180085323A1

公开(公告)日：2018-03-29

申请号：US15554923

申请日：2016-02-22

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Yoko FUJIWARA ,  Takashi YASUKOCHI ,  Yuka TAKAGI

IPC: A61K9/70 ,  A61K47/32 ,  A61K47/34 ,  A61K47/12 ,  A61K47/14 ,  A61M35/00

CPC classification number: A61K9/7061 ,  A61K9/7069 ,  A61K47/12 ,  A61K47/14 ,  A61K47/32 ,  A61K47/34 ,  A61M35/00

Abstract: A patch includes an adhesive layer and a release liner laminated on at least one surface of a backing. The adhesive layer comprises, as an adhesive base agent, at least one selected from the group consisting of acrylate-based adhesives and rubber-based adhesives, and the adhesive layer comprises 0.3 to 5% by mass of a nonfunctional silicone oil having a kinematic viscosity of 10 to 350 cSt at 25° C.