Abstract:
Provided are a polyester production apparatus and a method, which can rapidly exhaust water produced by the dehydration condensation reaction, from the reaction system.The polyester production apparatus includes: an esterification reactor producing polymer by the dehydration condensation reaction between 1,3-propanediol and dicarboxylic acid to volatilize a volatile component including eliminated water produced in said dehydration condensation reaction, a plurality of polymerization reactors increasing the polymerization degree by carrying out polycondensation reaction between polymers, and to volatilize the volatile component including the eliminated product generated by said polycondensation reaction, a wet-type condenser condensing said eliminated water and exhausting the condensed component and non-condensed component, and a decompression apparatus reducing a pressure in said esterification reactor. Said volatile component's outlet of said esterification reactor is connected to the volatile component's inlet of said wet-type condenser, and said decompression apparatus is connected next to the non-condensed component's outlet of said wet-type condenser.
Abstract:
This invention provides a culture control method and a cell culture apparatus that enable stable cell culture by regulating shear stress to be applied to cells within an adequate range. With the application of such culture control method and cell culture apparatus, cell culture is performed under agitation culture conditions in which the shear stress distribution is 0.5 Pa to 20 Pa in 80% or more of the culture vessel by volume.