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公开(公告)号：US3646045A
公开(公告)日：1972-02-29
申请号：US3646045D
申请日：1969-12-08
Applicant: HOFFMANN LA ROCHE
Inventor： BERGER LEO , CORRAZ ALFRED JOHN
IPC: C07D471/04 , C07D31/42
CPC classification number: C07D471/04
Abstract: 5 - (4-PYRIDYLETHYL)-PYRIDOINDOLE DERIVATIVES HAVING ANALGESIC ACTIVITY, PREPARED FROM THE CORRESPONDINGLY SUBSTITUTED 4-PIPERIDONES AND N-AMINO-N-ARYLAMINOETHYLPYRIDINES, ARE DESCRIBED. THE N-AMINO-N-ARYLAMINOETHYLPYRIDINES ARE PREPARED FROM THE SEQUENTIAL INTERMEDIATES NARYLAMINOETHYLPYRIDINES AND'' N-NITROSO-N-ARYLAMINOETHYLPYRIDINES.
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2.发明授权
公开(公告)号：US3868387A
公开(公告)日：1975-02-25
申请号：US32576473
申请日：1973-01-22
Applicant: HOFFMANN LA ROCHE
Inventor： BERGER LEO , CORRAZ ALFRED JOHN
IPC: C07D209/86 , C07D209/88 , C07D209/94 , C07D27/68
CPC classification number: C07D209/94 , C07D209/86 , C07D209/88
Abstract: 1,2,3,4-Tetrahydrocarbazoles and cyclopenta(b)indoles prepared from the corresponding phenyl hydrazines and corresponding cyclohexanones or cyclopentanones, respectively, are described. The products of the invention are useful anti-inflammatory, analgesic and anti-rheumatic agents.
Abstract translation: 描述了分别由对应的苯肼和相应的环己酮或环戊酮制备的1,2,3,4-四氢咔唑和环戊二烯并[b]吲哚。 本发明的产品是有用的抗炎，镇痛和抗风湿剂。
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公开(公告)号：US3654290A
公开(公告)日：1972-04-04
申请号：US3654290D
申请日：1970-03-27
Applicant: HOFFMANN LA ROCHE
Inventor： BERGER LEO , CORRAZ ALFRED JOHN
IPC: C07D213/38 , C07D213/42 , C07D471/04 , C07D31/42
CPC classification number: C07D213/42 , C07D213/38 , C07D471/04
Abstract: 5-(PYRIDYLAKYL)PYRIDOINDOLE DERIVATIVES HAVING ANTIALLERGIC ACTIVITY, PREPARED BY THE CONDENSATION OF THE CORRESPONDINGLY SUBSTITUTED 4-PIPERIDONES AND N-AMINO-NARLYAMINOALKYLPYRIDINES, ARE DESCRIBED.
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公开(公告)号：US3522262A
公开(公告)日：1970-07-28
申请号：US3522262D
申请日：1968-09-10
Applicant: HOFFMANN LA ROCHE
Inventor： BERGER LEO , CORRAZ ALFRED JOHN
IPC: C07D213/38 , C07D213/42 , C07D471/04 , C07D31/42
CPC classification number: C07D213/42 , C07D213/38 , C07D471/04
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Patent Agency Ranking
公开(公告)号：US3896145A
公开(公告)日：1975-07-22
申请号：US36110373
申请日：1973-05-17
Applicant: HOFFMANN LA ROCHE
Inventor： BERGER LEO , CORRAZ ALFRED JOHN
IPC: C07D209/86 , C07D209/88 , C07D27/68
CPC classification number: C07D209/86 , C07D209/88
Abstract: Carbazoles prepared, inter alia, from the corresponding phenyl hydrazines and corresponding cyclohexanones are described. The carbazoles of the invention are useful anti-inflammatory, analgesic and anti-rheumatic agents.
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公开(公告)号：US3502688A
公开(公告)日：1970-03-24
申请号：US3502688D
申请日：1968-09-10
Applicant: HOFFMANN LA ROCHE
Inventor： BERGER LEO , CORRAZ ALFRED JOHN
IPC: C07D213/38 , C07D213/42 , C07D471/04 , C07D31/36
CPC classification number: C07D213/42 , C07D213/38 , C07D471/04
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公开(公告)号：US3862953A
公开(公告)日：1975-01-28
申请号：US27559872
申请日：1972-07-27
Applicant: HOFFMANN LA ROCHE
Inventor： BERGER LEO , CORRAZ ALFRED JOHN
IPC: C07D213/38 , C07D213/42 , C07D213/55 , C07D213/56 , C07D31/40
CPC classification number: C07D213/42 , C07D213/38 , C07D213/55 , C07D213/56 , Y10S514/824
Abstract: 9-(Pyridylalkyl)-1,2,3,4-tetrahydrocarbazoles and 4(pyridylalkyl)-cyclopenta(b)indoles prepared by reacting the corresponding phenyl hydrazines and cyclohexanones or cyclopentanones, respectively, are described. The products of the invention are useful as antihyperlipidemic agents.
Abstract translation: 描述了分别通过相应的苯肼和环己酮或环戊酮与反应而制得的9-（吡啶基烷基）-1,2,3,4-四氢咔唑和4-（吡啶基烷基） - 环戊[b]吲哚。 本发明的产品可用作抗高脂血症药。
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公开(公告)号：US3531487A
公开(公告)日：1970-09-29
申请号：US3531487D
申请日：1966-10-25
Applicant: HOFFMANN LA ROCHE
Inventor： BERGER LEO , CORRAZ ALFRED JOHN , LEE JOHN
IPC: C07D211/02 , C07D211/58 , C07D211/72 , C07D29/28
CPC classification number: C07D211/72 , C07D211/02 , C07D211/58 , Y10S514/91
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公开(公告)号：US3484449A
公开(公告)日：1969-12-16
申请号：US3484449D
申请日：1968-02-09
Applicant: HOFFMANN LA ROCHE
Inventor： BERGER LEO , CORRAZ ALFRED JOHN
IPC: A61K31/00 , C07D213/38 , C07D213/42 , C07D471/04 , C07D31/42 , A61K15/12
CPC classification number: A61K31/00 , C07D213/38 , C07D213/42 , C07D471/04
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