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公开(公告)号：US20240252559A1
公开(公告)日：2024-08-01
申请号：US18561110
申请日：2022-03-22
IPC分类号： A61K35/747 , A61P19/10
CPC分类号： A61K35/747 , A61P19/10
摘要： A problem to be solved by the present invention is to provide a composition (1) for inhibiting differentiation of osteoclast precursor cells into osteoclasts, improving bone metabolism, and/or inhibiting bone density reduction, the composition (1) including a culture supernatant or a processed product thereof, the culture supernatant being obtainable by culturing immune cells in the presence of lactic acid bacteria or a processed product thereof, or a composition (2) for inhibiting differentiation of osteoclast precursor cells into osteoclasts, improving bone metabolism, and/or inhibiting bone density reduction, the composition (2) including Lactobacillus plantarum strain L-137 (Lactobacillus plantarum L-137) or a processed product thereof. These compositions solve the problem.
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公开(公告)号：US20230346858A1
公开(公告)日：2023-11-02
申请号：US18026464
申请日：2021-09-21
IPC分类号： A61K35/747 , A23K10/16 , A23K20/158 , A61P37/04 , A61K31/19 , A61P31/04
CPC分类号： A61K35/747 , A23K10/16 , A23K20/158 , A61P37/04 , A61K31/19 , A61P31/04 , C12R2001/25
摘要： A problem to be solved by the present invention is to provide one or more selected from (1) a feed comprising Lactobacillus plantarum strain L-137 or a processed product thereof and a fatty acid or a salt thereof, (2) a composition for enhancing IL-12 production, comprising Lactobacillus plantarum strain L-137 or a processed product thereof and a fatty acid or a salt thereof, (3) a composition for immunostimulation, comprising Lactobacillus plantarum strain L-137 or a processed product thereof and a fatty acid or a salt thereof, and (4) a composition for bacteriostasis, comprising Lactobacillus plantarum strain L-137 or a processed product thereof and a fatty acid or a salt thereof. The problem is solved by providing one or more of the feed or the compositions.
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