公开(公告)号：US20210038638A1

公开(公告)日：2021-02-11

申请号：US17077950

申请日：2020-10-22

Applicant: HOWARD UNIVERSITY

Inventor： James W MITCHELL ,  Dazhi YANG

IPC: A61K31/785 ,  A61K31/738 ,  B01J20/26 ,  B01J20/28 ,  B01J20/30 ,  A61P7/08 ,  C08B15/06 ,  C08G81/00 ,  C08G83/00 ,  C08J9/16 ,  A61K9/14 ,  C08F251/02 ,  C08G73/02 ,  C08L1/08 ,  C08L3/20 ,  C08L5/02 ,  C08L5/08

Abstract: Covalently cross-linked copolymers are described herein. More specifically, polysaccharide-polyamine copolymeric matrices or structures and cationic copolymeric matrices are described herein. The polysaccharide-polyamine copolymers, when protonated, can form cationic copolymeric matrices having exceptionally high densities of cationic sites. In one form, the covalently cross-linked copolymers provide a three-dimensional structure, especially when hydrated.

公开(公告)号：US20250082668A1

公开(公告)日：2025-03-13

申请号：US18959847

申请日：2024-11-26

Applicant: Howard University

Inventor： James W. MITCHELL ,  Dazhi YANG

IPC: A61K31/785 ,  A61K9/14 ,  A61K31/738 ,  A61P7/08 ,  B01J20/26 ,  B01J20/28 ,  B01J20/30 ,  C08B15/06 ,  C08F251/02 ,  C08G73/02 ,  C08G81/00 ,  C08G83/00 ,  C08G101/00 ,  C08J9/16 ,  C08L1/08 ,  C08L3/20 ,  C08L5/02 ,  C08L5/08

Abstract: Covalently cross-linked copolymers are described herein. More specifically, polysaccharide-polyamine copolymeric matrices or structures and cationic copolymeric matrices are described herein. The polysaccharide-polyamine copolymers, when protonated, can form cationic copolymeric matrices having exceptionally high densities of cationic sites. In one form, the covalently cross-linked copolymers provide a three-dimensional structure, especially when hydrated.