公开(公告)号：US11981630B1

公开(公告)日：2024-05-14

申请号：US18103843

申请日：2023-01-31

申请人： Hangzhou Normal University

发明人： Mingfeng Xu ,  Xiaohong Deng ,  Jinfeng Liang ,  Yidi Chen ,  Jing Ren ,  Qin Zhu

IPC分类号： C07C49/747 ,  A61P35/02 ,  C07C45/79

CPC分类号： C07C49/747 ,  A61P35/02 ,  C07C45/79 ,  C07C2603/26

摘要： Disclosed are an abietane type diterpene compound, a preparation method and an application thereof, relating to the technical field of anti-tumor compounds, where the compound has a chemical structure as shown in the following formula I:




Leucosceptrum canum is extracted to prepare the abietane type diterpene compound according to the present application, and the prepared compound is effectively applied in inhibiting human lung cancer cell A549 and human myeloid leukemia cell HL-60.