专利检索 ap:("Hans-Peter VORNLOCHER" OR "Ingo ROEHL" OR "Philipp HADWIGER" OR "Tracy Stage ZIMMERMANN" OR "Muthiah MANOHARAN" OR "Kallanthottathil G. RAJEEV" OR "Akin AKINC") AND inv:"Tracy Stage ZIMMERMANN" 第 1 页

1.

发明申请
NUCLEASE RESISTANT DOUBLE-STRANDED RIBONUCLEIC ACID 审中-公开
标题翻译：抗核抗原双重抗坏血酸

公开(公告)号：US20130150570A1

公开(公告)日：2013-06-13

申请号：US13431376

申请日：2012-03-27

申请人： Hans-Peter VORNLOCHER , Ingo ROEHL , Philipp HADWIGER , Tracy Stage ZIMMERMANN , Muthiah MANOHARAN , Kallanthottathil G. RAJEEV , Akin AKINC

发明人： Hans-Peter VORNLOCHER , Ingo ROEHL , Philipp HADWIGER , Tracy Stage ZIMMERMANN , Muthiah MANOHARAN , Kallanthottathil G. RAJEEV , Akin AKINC

IPC分类号： C07H21/02

CPC分类号： C07H21/02 , C12N15/111 , C12N15/113 , C12N2310/14 , C12N2310/315 , C12N2310/318 , C12N2310/321 , C12N2310/322 , C12N2310/323 , C12N2310/3231 , C12N2310/53 , C12N2320/51 , C12N2310/3521 , C12N2310/3525 , C12N2310/3527

摘要： This invention relates to modified double-stranded oligoribonucleic acid (dsRNA) having improved stability in cells and biological fluids, and methods of making and identifying dsRNA having improved stability, and of using the dsRNA to inhibit the expression or function of a target gene.

摘要翻译： 本发明涉及在细胞和生物流体中具有改善的稳定性的修饰的双链寡核糖核酸（dsRNA），以及制备和鉴定具有改善的稳定性的dsRNA的方法，以及使用dsRNA抑制靶基因的表达或功能。

2.

发明申请
NUCLEASE RESISTANT DOUBLE-STRANDED RIBONUCLEIC ACID 有权
标题翻译：抗核抗原双重抗坏血酸

公开(公告)号：US20110245320A1

公开(公告)日：2011-10-06

申请号：US13038672

申请日：2011-03-02

申请人： Hans-Peter VORNLOCHER , Ingo ROEHL , Philipp HADWIGER , Tracy Stage ZIMMERMANN , Muthiah MANOHARAN , Kallanthottathil G. RAJEEV , Akin AKINC

发明人： Hans-Peter VORNLOCHER , Ingo ROEHL , Philipp HADWIGER , Tracy Stage ZIMMERMANN , Muthiah MANOHARAN , Kallanthottathil G. RAJEEV , Akin AKINC

IPC分类号： A61K31/713 , C07H21/02 , A61P43/00

CPC分类号： C07H21/02 , C12N15/111 , C12N15/113 , C12N2310/14 , C12N2310/315 , C12N2310/318 , C12N2310/321 , C12N2310/322 , C12N2310/323 , C12N2310/3231 , C12N2310/53 , C12N2320/51 , C12N2310/3521 , C12N2310/3525 , C12N2310/3527

摘要： This invention relates to modified double-stranded oligoribonucleic acid (dsRNA) having improved stability in cells and biological fluids, and methods of making and identifying dsRNA having improved stability, and of using the dsRNA to inhibit the expression or function of a target gene.

摘要翻译： 本发明涉及在细胞和生物流体中具有改善的稳定性的修饰的双链寡核糖核酸（dsRNA），以及制备和鉴定具有改善的稳定性的dsRNA的方法，以及使用dsRNA抑制靶基因的表达或功能。