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    Devices and methods for performing a vascular anastomosis
    1.
    发明授权
    Devices and methods for performing a vascular anastomosis 失效
    用于进行血管吻合的装置和方法

    公开(公告)号：US5695504A

    公开(公告)日：1997-12-09

    申请号：US394333

    申请日：1995-02-24

    申请人： Hanson S. Gifford, III ,  Lee R. Bolduc ,  Jeffrey A. Stein ,  Paul C. DiCesare ,  Peter F. Costa ,  William A. Holmes

    发明人： Hanson S. Gifford, III ,  Lee R. Bolduc ,  Jeffrey A. Stein ,  Paul C. DiCesare ,  Peter F. Costa ,  William A. Holmes

    IPC分类号： A61B17/00 ,  A61B17/064 ,  A61B17/068 ,  A61B17/11 ,  A61B17/115 ,  A61B17/12 ,  A61F2/00 ,  A61B17/08 ,  A61B17/10

    CPC分类号： A61B17/068 ,  A61B17/064 ,  A61B17/115 ,  A61B17/12036 ,  A61B17/12045 ,  A61B17/12109 ,  A61B17/12136 ,  A61B17/0643 ,  A61B17/11 ,  A61B2017/00243 ,  A61B2017/0641 ,  A61B2017/0647 ,  A61B2017/1103 ,  A61B2017/1107 ,  A61B2017/1135 ,  A61B2017/12127 ,  A61F2002/30092 ,  A61F2210/0014

    摘要： A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel. A tailored amount of compression applied by the inner and outer flanges grips the target vessel wall and creates a leak-proof seal between the graft vessel and the target vessel. A third aspect of the invention has a flange to which the graft vessel attaches, by everting the graft vessel over the flange, and a plurality of staple-like members which attach the flange and the everted end of the graft vessel to the wall of the target vessel to form the anastomosis.

    摘要翻译： 一种用于执行端对侧血管吻合的系统，包括吻合装置，应用仪器和用于进行血管吻合的方法。 该系统适用于在冠状动脉旁路手术中进行血管移植物和升主动脉之间的吻合，特别是在进入CABG手术中。 本发明的第一方面包括血管吻合缝合物。 第一构造具有两部分：锚定构件，与目标血管壁形成附件和联接构件，与旁路移植血管形成附件。 通过将连接构件插入到锚定构件中来完成吻合。 第二种结构将锚定构件和联接构件的功能结合成一体式吻合钉。 本发明的第二方面包括一种吻合装置，其具有内部凸缘，移植物容器在其上延伸，外部凸缘接触目标血管的外表面。 由内外法兰施加的定制的压缩量夹住目标血管壁，并在移植血管和靶血管之间产生防漏密封。 本发明的第三方面具有凸缘，移植管通过使移植物容器穿过凸缘而附接到该凸缘上，以及多个钉状构件，其将该移植物容器的凸缘和脱出端附接到 靶血管形成吻合。

    Devices and methods for performing avascular anastomosis
    2.
    发明授权
    Devices and methods for performing avascular anastomosis 有权
    用于进行无血管吻合的装置和方法

    公开(公告)号：US07112211B2

    公开(公告)日：2006-09-26

    申请号：US10339434

    申请日：2003-01-09

    申请人： Hanson S. Gifford, III ,  Lee R. Bolduc ,  Jeffrey A. Stein ,  Paul C. DiCesare ,  Peter F. Costa ,  William A. Holmes

    发明人： Hanson S. Gifford, III ,  Lee R. Bolduc ,  Jeffrey A. Stein ,  Paul C. DiCesare ,  Peter F. Costa ,  William A. Holmes

    IPC分类号： A61B17/11

    CPC分类号： A61B17/12109 ,  A61B17/064 ,  A61B17/0643 ,  A61B17/11 ,  A61B17/115 ,  A61B17/12036 ,  A61B17/12045 ,  A61B17/12136 ,  A61B2017/00243 ,  A61B2017/0641 ,  A61B2017/1135 ,  A61B2017/12127 ,  A61F2002/30092 ,  A61F2210/0014

    摘要： A system for performing an end-to-side vascular anastomosis. including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel. A tailored amount of compression applied by the inner and outer flanges grips the target vessel wall and creates a leak-proof seal between the graft vessel and the target vessel. A third aspect of the invention has a flange to which the graft vessel attaches, by everting the graft vessel over the flange, and a plurality of staple-like members which attach the flange and the everted end of the graft vessel to the wall of the target vessel to form the anastomosis.

    摘要翻译： 用于进行端对侧血管吻合的系统。 包括吻合装置，应用仪器和用于进行血管吻合的方法。 该系统适用于在冠状动脉旁路手术中进行血管移植物和升主动脉之间的吻合，特别是在进入CABG手术中。 本发明的第一方面包括血管吻合缝合物。 第一构造具有两部分：锚定构件，与目标血管壁形成附件和联接构件，与旁路移植血管形成附件。 通过将连接构件插入到锚定构件中来完成吻合。 第二种结构将锚定构件和联接构件的功能结合成一体式吻合钉。 本发明的第二方面包括一种吻合装置，其具有内部凸缘，移植物容器在其上延伸，外部凸缘接触目标血管的外表面。 由内外法兰施加的定制的压缩量夹住目标血管壁，并在移植血管和靶血管之间产生防漏密封。 本发明的第三方面具有凸缘，移植管通过使移植物容器穿过凸缘而附接到该凸缘上，以及多个钉状构件，其将该移植物容器的凸缘和脱出端附接到 靶血管形成吻合。

    Devices and methods for performing a vascular anastomosis
    5.
    发明授权
    Devices and methods for performing a vascular anastomosis 有权
    用于进行血管吻合的装置和方法

    公开(公告)号：US06171321B2

    公开(公告)日：2001-01-09

    申请号：US09315365

    申请日：1999-05-18

    申请人： Hanson S. Gifford, III ,  Lee R. Bolduc ,  Jeffrey A. Stein ,  Paul C. DiCesare ,  Peter F. Costa ,  William A. Holmes

    发明人： Hanson S. Gifford, III ,  Lee R. Bolduc ,  Jeffrey A. Stein ,  Paul C. DiCesare ,  Peter F. Costa ,  William A. Holmes

    IPC分类号： A61B1711

    CPC分类号： A61B17/12109 ,  A61B17/064 ,  A61B17/0643 ,  A61B17/11 ,  A61B17/115 ,  A61B17/12036 ,  A61B17/12045 ,  A61B17/12136 ,  A61B2017/00243 ,  A61B2017/0641 ,  A61B2017/1135 ,  A61B2017/12127 ,  A61F2002/30092 ,  A61F2210/0014

    摘要： A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member. forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel. A tailored amount of compression applied by the inner and outer flanges grips the target vessel wall and creates a leak-proof seal between the graft vessel and the target vessel. A third aspect of the invention has a flange to which the graft vessel attaches, by everting the graft vessel over the flange, and a plurality of staple-like members which attach the flange and the everted end of the graft vessel to the wall of the target vessel to form the anastomosis.

    摘要翻译： 一种用于执行端对侧血管吻合的系统，包括吻合装置，应用仪器和用于进行血管吻合的方法。 该系统适用于在冠状动脉旁路手术中进行血管移植物和升主动脉之间的吻合，特别是在进入CABG手术中。 本发明的第一方面包括血管吻合缝合物。 第一构造具有两部分：锚定构件，与靶血管壁形成附件和联接构件。 用旁路移植血管形成附件。 通过将连接构件插入到锚定构件中来完成吻合。 第二种结构将锚定构件和联接构件的功能结合成一体式吻合钉。 本发明的第二方面包括一种吻合装置，其具有内部凸缘，移植物容器在其上延伸，外部凸缘接触目标血管的外表面。 由内外法兰施加的定制的压缩量夹住目标血管壁，并在移植血管和靶血管之间产生防漏密封。 本发明的第三方面具有凸缘，移植管通过使移植物容器穿过凸缘而附接到该凸缘上，以及多个钉状构件，其将该移植物容器的凸缘和脱出端附接到 靶血管形成吻合。

    Device For Engaging Tissue Having a Preexisting Opening
    6.
    发明申请
    Device For Engaging Tissue Having a Preexisting Opening 失效
    用于使具有预先存在的开口的组织的装置

    公开(公告)号：US20110172686A1

    公开(公告)日：2011-07-14

    申请号：US13073119

    申请日：2011-03-28

    申请人： Hanson S. Gifford, III ,  Lee R. Bolduc ,  Jeffrey A. Stein ,  Paul C. Dicesare ,  Peter F. Costa ,  William A. Holmes

    发明人： Hanson S. Gifford, III ,  Lee R. Bolduc ,  Jeffrey A. Stein ,  Paul C. Dicesare ,  Peter F. Costa ,  William A. Holmes

    IPC分类号： A61B17/11 ,  A61B17/064

    CPC分类号： A61B17/12109 ,  A61B17/064 ,  A61B17/0643 ,  A61B17/11 ,  A61B17/115 ,  A61B17/12036 ,  A61B17/12045 ,  A61B17/12136 ,  A61B2017/00243 ,  A61B2017/0641 ,  A61B2017/1135 ,  A61B2017/12127 ,  A61F2002/30092 ,  A61F2210/0014

    摘要： A system for performing an end-to-side vascular anastomosis. including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel. A tailored amount of compression applied by the inner and outer flanges grips the target vessel wall and creates a leak-proof seal between the graft vessel and the target vessel. A third aspect of the invention has a flange to which the graft vessel attaches, by everting the graft vessel over the flange, and a plurality of staple-like members which attach the flange and the everted end of the graft vessel to the wall of the target vessel to form the anastomosis

    摘要翻译： 用于进行端对侧血管吻合的系统。 包括吻合装置，应用仪器和用于进行血管吻合的方法。 该系统适用于在冠状动脉旁路手术中进行血管移植物和升主动脉之间的吻合，特别是在进入CABG手术中。 本发明的第一方面包括血管吻合缝合物。 第一构造具有两部分：锚定构件，与目标血管壁形成附件和联接构件，与旁路移植血管形成附件。 通过将连接构件插入到锚定构件中来完成吻合。 第二种结构将锚定构件和联接构件的功能结合成一体式吻合钉。 本发明的第二方面包括一种吻合装置，其具有内部凸缘，移植物容器在其上延伸，外部凸缘接触目标血管的外表面。 由内外法兰施加的定制的压缩量夹住目标血管壁，并在移植血管和靶血管之间产生防漏密封。 本发明的第三方面具有凸缘，移植管通过使移植物容器穿过凸缘而附接到该凸缘上，以及多个钉状构件，其将该移植物容器的凸缘和脱出端附接到 靶血管形成吻合

    Devices and methods for performing avascular anastomosis
    7.
    发明授权
    Devices and methods for performing avascular anastomosis 失效
    用于进行无血管吻合的装置和方法

    公开(公告)号：US06899718B2

    公开(公告)日：2005-05-31

    申请号：US10830897

    申请日：2004-04-23

    申请人： Hanson S. Gifford, III ,  Lee R. Bolduc ,  Jeffrey A. Stein ,  Paul C. DiCesare ,  Peter F. Costa ,  William A. Holmes

    发明人： Hanson S. Gifford, III ,  Lee R. Bolduc ,  Jeffrey A. Stein ,  Paul C. DiCesare ,  Peter F. Costa ,  William A. Holmes

    IPC分类号： A61B17/00 ,  A61B17/064 ,  A61B17/11 ,  A61B17/115 ,  A61B17/12 ,  A61F2/00

    CPC分类号： A61B17/12109 ,  A61B17/064 ,  A61B17/0643 ,  A61B17/11 ,  A61B17/115 ,  A61B17/12036 ,  A61B17/12045 ,  A61B17/12136 ,  A61B2017/00243 ,  A61B2017/0641 ,  A61B2017/1135 ,  A61B2017/12127 ,  A61F2002/30092 ,  A61F2210/0014

    摘要： A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel. A tailored amount of compression applied by the inner and outer flanges grips the target vessel wall and creates a leak-proof seal between the graft vessel and the target vessel. A third aspect of the invention has a flange to which the graft vessel attaches, by everting the graft vessel over the flange, and a plurality of staple-like members which attach the flange and the everted end of the graft vessel to the wall of the target vessel to form the anastomosis

    摘要翻译： 一种用于执行端对侧血管吻合的系统，包括吻合装置，应用仪器和用于进行血管吻合的方法。 该系统适用于在冠状动脉旁路手术中进行血管移植物和升主动脉之间的吻合，特别是在进入CABG手术中。 本发明的第一方面包括血管吻合缝合物。 第一构造具有两部分：锚定构件，与目标血管壁形成附件和联接构件，与旁路移植血管形成附件。 通过将连接构件插入到锚定构件中来完成吻合。 第二种结构将锚定构件和联接构件的功能结合成一体式吻合钉。 本发明的第二方面包括一种吻合装置，其具有内部凸缘，移植物容器在其上延伸，外部凸缘接触目标血管的外表面。 由内外法兰施加的定制的压缩量夹住目标血管壁，并在移植血管和靶血管之间产生防漏密封。 本发明的第三方面具有凸缘，移植管通过使移植物容器穿过凸缘而附接到该凸缘上，以及多个钉状构件，其将该移植物容器的凸缘和脱出端附接到 靶血管形成吻合

    Device for engaging tissue having a preexisting opening
    9.
    发明授权
    Device for engaging tissue having a preexisting opening 失效
    用于接合具有预先存在的开口的组织的装置

    公开(公告)号：US08617190B2

    公开(公告)日：2013-12-31

    申请号：US13073119

    申请日：2011-03-28

    申请人： Hanson S. Gifford, III ,  Lee R. Bolduc ,  Jeffrey A. Stein ,  Paul C. DiCesare ,  Peter F. Costa ,  William A. Holmes

    发明人： Hanson S. Gifford, III ,  Lee R. Bolduc ,  Jeffrey A. Stein ,  Paul C. DiCesare ,  Peter F. Costa ,  William A. Holmes

    IPC分类号： A61B17/11

    CPC分类号： A61B17/12109 ,  A61B17/064 ,  A61B17/0643 ,  A61B17/11 ,  A61B17/115 ,  A61B17/12036 ,  A61B17/12045 ,  A61B17/12136 ,  A61B2017/00243 ,  A61B2017/0641 ,  A61B2017/1135 ,  A61B2017/12127 ,  A61F2002/30092 ,  A61F2210/0014

    摘要： A system for performing an end-to-side vascular anastomosis, including an anastomosis device, an application instrument and methods for performing a vascular anastomosis. The system is applicable for performing an anastomosis between a vascular graft and the ascending aorta in coronary artery bypass surgery, particularly in port-access CABG surgery. A first aspect of the invention includes a vascular anastomosis staple. A first configuration has two parts: an anchor member, forming the attachment with the target vessel wall and a coupling member, forming the attachment with the bypass graft vessel. The anastomosis is completed by inserting the coupling member, with the graft vessel attached, into the anchor member. A second configuration combines the functions of the anchor member and the coupling member into a one-piece anastomosis staple. A second aspect of the invention includes an anastomotic fitting, having an inner flange over which the graft vessel is everted and an outer flange which contacts the exterior surface of the target vessel. A tailored amount of compression applied by the inner and outer flanges grips the target vessel wall and creates a leak-proof seal between the graft vessel and the target vessel. A third aspect of the invention has a flange to which the graft vessel attaches, by everting the graft vessel over the flange, and a plurality of staple-like members which attach the flange and the everted end of the graft vessel to the wall of the target vessel to form the anastomosis.

    摘要翻译： 一种用于执行端对侧血管吻合的系统，包括吻合装置，应用仪器和用于进行血管吻合的方法。 该系统适用于在冠状动脉旁路手术中进行血管移植物和升主动脉之间的吻合，特别是在进入CABG手术中。 本发明的第一方面包括血管吻合缝合物。 第一构造具有两部分：锚定构件，与目标血管壁形成附件和联接构件，与旁路移植血管形成附件。 通过将连接构件插入到锚定构件中来完成吻合。 第二种结构将锚定构件和联接构件的功能结合成一体式吻合钉。 本发明的第二方面包括一种吻合装置，其具有内部凸缘，移植物容器在其上延伸，外部凸缘接触目标血管的外表面。 由内外法兰施加的定制的压缩量夹住目标血管壁，并在移植血管和靶血管之间产生防漏密封。 本发明的第三方面具有凸缘，移植管通过使移植物容器穿过凸缘而附接到该凸缘上，以及多个钉状构件，其将该移植物容器的凸缘和脱出端附接到 靶血管形成吻合。