公开(公告)号：US20120183509A1

公开(公告)日：2012-07-19

申请号：US13266858

申请日：2010-04-28

申请人： Harald Neumann ,  Martin Glas ,  Ruslan Masgutov ,  Ulrich Herrlinger ,  Kristian Welle

发明人： Harald Neumann ,  Martin Glas ,  Ruslan Masgutov ,  Ulrich Herrlinger ,  Kristian Welle

IPC分类号： A61K35/30 ,  A61P35/00 ,  C12N5/0735 ,  C12N5/071

CPC分类号： A61K35/30 ,  A61K35/12 ,  C12N5/0622 ,  C12N2500/25 ,  C12N2500/32 ,  C12N2500/38 ,  C12N2500/44 ,  C12N2500/50 ,  C12N2501/22 ,  C12N2501/2303 ,  C12N2501/235 ,  C12N2501/58 ,  C12N2506/02

摘要： Microglial precursor cells for use in the treatment of malignant neoplasms of the central nervous system. A method of treating malignant neoplasms of the central nervous system comprising administering a pharmaceutically effective amount of microglial precursor cells to a subject in need thereof.

摘要翻译： 用于治疗中枢神经系统恶性肿瘤的小胶质前体细胞。 一种治疗中枢神经系统的恶性肿瘤的方法，包括向有需要的受试者施用药学有效量的小胶质前体细胞。

公开(公告)号：US20120107898A1

公开(公告)日：2012-05-03

申请号：US13266845

申请日：2010-04-28

申请人： Harald Neumann ,  Kristin Roy ,  Oliver Brüstle ,  Michael Peitz

发明人： Harald Neumann ,  Kristin Roy ,  Oliver Brüstle ,  Michael Peitz

IPC分类号： C12N13/00 ,  C12N5/071

CPC分类号： A61K35/30 ,  A61K35/12 ,  C12N5/0622 ,  C12N2500/25 ,  C12N2500/32 ,  C12N2500/38 ,  C12N2500/44 ,  C12N2500/50 ,  C12N2501/22 ,  C12N2501/2303 ,  C12N2501/235 ,  C12N2501/58 ,  C12N2506/02

摘要： A method for obtaining human microglial precursor cells, comprising: (a) providing a cell population comprising neural precursor cells, wherein the cell population is obtainable from embryoid bodies differentiated from human pluripotent stem cells; (b) differentiating the cell population comprising neural precursor cells into microglial precursor cells by culturing in medium comprising a growth factor selected from the group consisting of insulin and insulin-like growth factors; (c) expanding and enriching microglial precursor cells in medium comprising a growth factor selected from the group consisting of insulin and insulin-like growth factors and 10 to 150 ng/ml GM-CSF; and (d) isolating microglial precursor cells comprising CD45-positive cells.

摘要翻译： 一种获得人小胶质细胞前体细胞的方法，包括：（a）提供包含神经前体细胞的细胞群，其中所述细胞群可从人多能干细胞分化的胚状体获得; （b）通过在包含选自胰岛素和胰岛素样生长因子的生长因子的培养基中培养将包含神经前体细胞的细胞群分化为小胶质前体细胞; （c）在包含选自胰岛素和胰岛素样生长因子和10至150ng / ml GM-CSF的生长因子的培养基中扩增和富集小神经胶质前体细胞; 和（d）分离包含CD45阳性细胞的小胶质前体细胞。

公开(公告)号：US20100180974A1

公开(公告)日：2010-07-22

申请号：US12688225

申请日：2010-01-15

申请人： Stefan Gross ,  Harald Neumann

发明人： Stefan Gross ,  Harald Neumann

IPC分类号： F16L25/00

CPC分类号： F16L3/1226 ,  F16L35/00 ,  F16L57/02

摘要： The present embodiments relate to an apparatus which can be used to increase the bending strength of a tube in its connection region. The apparatus may include an adapter unit, the shape of which is matched to a cross-sectional shape of a tube end in such a manner that on the one hand the adapter unit can be fitted to a tube connection of a device instead of the tube end and on the other hand the tube end can be fitted to the adapter unit. The apparatus may also include at least one spring element made of glass fiber reinforced plastic, which is connected to the adapter unit, projects out of the adapter unit in the direction of the tube and has a termination element at the projecting end, against which termination element a fitted tube abuts when subjected to bending, so that the rigidity of the spring element increases the bending strength of the tube in the region between the adapter unit and the element.

摘要翻译： 本实施例涉及一种可用于增加其连接区域中的管的弯曲强度的装置。 该装置可以包括适配器单元，其形状与管端的横截面形状相匹配，使得一方面可将适配器单元装配到设备的管连接件而不是管 另一方面，管端可以装配到适配器单元。 该装置还可以包括连接到适配器单元的由玻璃纤维增​​强塑料制成的至少一个弹簧元件，沿着管的方向从适配器单元突出，并且在突出端处具有终端元件，该终端 元件一个装配的管子在经受弯曲时抵接，使得弹簧元件的刚性增加了在适配器单元和元件之间的区域中的管的弯曲强度。

公开(公告)号：US06645361B1

公开(公告)日：2003-11-11

申请号：US09936815

申请日：2002-01-14

申请人： Bernhard Bloemer ,  Rainer Strohmaier ,  Carsten Springhorn ,  Detlef Heimann ,  Hans-Joerg Renz ,  Harald Neumann ,  Margret Schuele ,  Bernd Schumann ,  Thomas Moser ,  Sabine Thiemann-Handler

发明人： Bernhard Bloemer ,  Rainer Strohmaier ,  Carsten Springhorn ,  Detlef Heimann ,  Hans-Joerg Renz ,  Harald Neumann ,  Margret Schuele ,  Bernd Schumann ,  Thomas Moser ,  Sabine Thiemann-Handler

IPC分类号： G01N27407

CPC分类号： G01N27/417

摘要： An electrochemical gas sensor for determining the concentration of gas components in a gas mixture, in particular for determining NOx and HC. The gas sensor includes a first measuring gas space which is connected to the measuring gas, and a second measuring gas space which is connected to the first measuring gas space by a connecting channel. Furthermore, a first electrode and a second electrode, arranged in the first measuring gas space, and at least one third electrode arranged in the second measuring gas space, and at least one fourth electrode are provided. The two measuring gas spaces are arranged in layer planes on top of one another and are separated from one another by at least one oxygen ion conducting layer, the connecting channel passing through the oxygen ion conducting layer.

摘要翻译： 一种电化学气体传感器，用于确定气体混合物中气体组分的浓度，特别是用于确定NOx和HC。 气体传感器包括连接到测量气体的第一测量气体空间和通过连接通道连接到第一测量气体空间的第二测量气体空间。 此外，设置有布置在第一测量气体空间中的第一电极和第二电极以及布置在第二测量气体空间中的至少一个第三电极和至少一个第四电极。 两个测量气体空间在彼此顶部的层平面中排列，并且通过至少一个氧离子传导层彼此分离，连接通道穿过氧离子传导层。

公开(公告)号：US06350357B1

公开(公告)日：2002-02-26

申请号：US09142599

申请日：1999-06-17

申请人： Hans-Martin Wiedenmann ,  Harald Neumann ,  Karl-Heinz Heussner

发明人： Hans-Martin Wiedenmann ,  Harald Neumann ,  Karl-Heinz Heussner

IPC分类号： G01N27407

CPC分类号： G01N27/4071

摘要： A plate-shaped sensor element is proposed, in particular for determining the oxygen level in exhaust gases of internal combustion engines. The sensor element has at least one measuring cell with an oxygen-ion-conducting solid electrolyte and a heating element, the measuring cell and the heating element being connected with an electrical insulation layer. The material of the insulation layer is made of at least one crystalline, non-metallic material and at least one glass-forming material, a glazing filled with the crystalline, non-metallic material being formed when the sensor element is sintered.

摘要翻译： 提出了一种板状传感器元件，特别是用于确定内燃机废气中的氧气含量。 传感器元件具有至少一个具有氧离子传导固体电解质和加热元件的测量单元，测量单元和加热元件与电绝缘层连接。 绝缘层的材料由至少一种结晶非金属材料和至少一种玻璃形成材料制成，当传感器元件被烧结时，填充有结晶非金属材料的玻璃窗。

公开(公告)号：US5595647A

公开(公告)日：1997-01-21

申请号：US290703

申请日：1995-01-19

申请人： Gerhard Hoetzel ,  Harald Neumann ,  Johann Riegel

发明人： Gerhard Hoetzel ,  Harald Neumann ,  Johann Riegel

IPC分类号： G01N27/419 ,  G01N27/12 ,  G01N27/407 ,  G01N27/41

CPC分类号： G01N27/407 ,  G01N27/4074

摘要： A method of determining at least one of gas constituents and gas concentrations of a gas mixture such as exhaust gas from an internal combustion engine includes producing a change in gas concentration of the gas mixture at a semiconductor gas sensor by pumping a variable supply of oxygen to the semiconductor gas sensor by means of a solid electrolyte pumping cell; detecting at least one reaction speed selected from the group consisting of adsorption speed and desorption speed caused by the change in gas concentration as a signal from the semiconductor gas sensor which is a reply function; evaluating the signal from the semiconductor gas sensor over time to provide a time response of the reply function; and comparing the time response of the reply function with a stored, standardized time response of different gas constituents whereby at least one of the gas constituents and the gas concentrations of the gas mixture are determined.

摘要翻译： PCT No.PCT / DE94 / 00188 Sec。 371日期1995年1月19日 102（e）日期1995年1月19日PCT 1994年2月19日PCT PCT。 公开号WO94 / 22007 日期1994年9月29日一种确定气体混合物（例如来自内燃机的废气）的气体组分和气体浓度中的至少一种的方法包括通过泵送一个半导体气体传感器来产生气体混合物的气体浓度的变化 通过固体电解质泵送单元向半导体气体传感器供应氧气; 检测从由作为回复功能的半导体气体传感器的信号的气体浓度的变化引起的吸附速度和解吸速度中选择的至少一个反应速度; 评估来自半导体气体传感器的信号随时间提供回复功能的时间响应; 以及将回复函数的时间响应与不同气体成分的存储的，标准化的时间响应进行比较，由此确定气体混合物的气体成分和气体浓度中的至少一种。

公开(公告)号：US09289902B2

公开(公告)日：2016-03-22

申请号：US12889024

申请日：2010-09-23

申请人： Stefan Groβ ,  Harald Neumann ,  Franz Schmeisser

发明人： Stefan Groβ ,  Harald Neumann ,  Franz Schmeisser

IPC分类号： B25J18/00 ,  B25J19/00 ,  A61B6/00 ,  H02G11/02

CPC分类号： B25J19/0025 ,  A61B6/4458 ,  A61B6/56 ,  H02G11/02 ,  Y10T74/20311

摘要： An arrangement includes a robot having a robot arm that supports a device powered by supply lines. The arrangement includes at least one guide element that is fastened to the robot arm, and the supply lines are moveably held against at least one segment of the robot arm by the at least one guide element. At least one storage element is provided for receiving a supply line provision. The at least one storage element releases the supply line from the supply line provision with an increasing tensile load of the supply lines and retracts the supply line into the supply line provision with a decreasing tensile load of the supply lines.

摘要翻译： 一种装置包括具有支撑由供给线供电的装置的机器人手臂的机器人。 该装置包括紧固到机器人臂的至少一个引导元件，并且供应线通过至少一个引导元件可移动地保持抵靠机器人手臂的至少一个部分。 提供至少一个存储元件用于接收供应线条。 所述至少一个存储元件以供应线的增加的拉伸载荷将所述供应管线从所述供应管线释放释放，并且在所述供应管线的拉伸载荷减小的情况下将所述供应管线缩回到所述供应管线中。

公开(公告)号：US08414189B2

公开(公告)日：2013-04-09

申请号：US12846513

申请日：2010-07-29

申请人： Stefan Groβ ,  Harald Neumann ,  Frank Rosinus

发明人： Stefan Groβ ,  Harald Neumann ,  Frank Rosinus

IPC分类号： F16C29/04

CPC分类号： H02G3/32 ,  F16L3/18 ,  Y10T16/05

摘要： A guide element for a corrugated tube is formed as a ring. At least one rotating roller is integrated in the interior of the ring such that the at least one rotating roller contacts the corrugated tube when the corrugated tube is passed through the ring. The at least one rotating roller rotates with a movement of the corrugated tube using the guide element. The guide element enables low-wear control of corrugated tubes.

摘要翻译： 用于波纹管的引导元件形成为环。 至少一个旋转辊集成在环的内部，使得当波纹管穿过环时，至少一个旋转辊接触波纹管。 所述至少一个旋转辊随着使用引导元件的波纹管的移动而旋转。 引导元件能够对波纹管进行低磨损控制。

公开(公告)号：US20110100684A1

公开(公告)日：2011-05-05

申请号：US12810738

申请日：2008-12-19

申请人： Peter Hornig ,  Mark Leverkoehne ,  Philipp Janovsky ,  Bernd Maihoefer ,  Juergen Egerter ,  Walter Roethlingshofer ,  Stefan Keil ,  Harald Neumann ,  Heike Schluckwerder ,  Markus Werner ,  Ulrich Speh ,  Frank Westphal ,  Josef Weber

发明人： Peter Hornig ,  Mark Leverkoehne ,  Philipp Janovsky ,  Bernd Maihoefer ,  Juergen Egerter ,  Walter Roethlingshofer ,  Stefan Keil ,  Harald Neumann ,  Heike Schluckwerder ,  Markus Werner ,  Ulrich Speh ,  Frank Westphal ,  Josef Weber

IPC分类号： H05K1/02 ,  H05K3/10 ,  H01C17/065 ,  B05D3/06

CPC分类号： H05K1/167 ,  H01C17/06506 ,  H05K3/1241 ,  H05K2203/0126 ,  H05K2203/0545

摘要： A method for manufacturing an electrical conductor by applying at least one paste, in particular a thick-film paste, to a substrate by a dispensing operation, wherein the paste is applied in at least one strand.

摘要翻译： 一种用于通过分配操作将至少一种浆料，特别是厚膜浆料施加到基材上来制造电导体的方法，其中所述糊料以至少一根线材施加。

公开(公告)号：US20110072931A1

公开(公告)日：2011-03-31

申请号：US12889024

申请日：2010-09-23

申请人： Stefan Groß ,  Harald Neumann ,  Franz Schmeisser

发明人： Stefan Groß ,  Harald Neumann ,  Franz Schmeisser

IPC分类号： B25J18/00

CPC分类号： B25J19/0025 ,  A61B6/4458 ,  A61B6/56 ,  H02G11/02 ,  Y10T74/20311

摘要： An arrangement includes a robot having a robot arm that supports a device powered by supply lines. The arrangement includes at least one guide element that is fastened to the robot arm, and the supply lines are moveably held against at least one segment of the robot arm by the at least one guide element. At least one storage element is provided for receiving a supply line provision. The at least one storage element releases the supply line from the supply line provision with an increasing tensile load of the supply lines and retracts the supply line into the supply line provision with a decreasing tensile load of the supply lines.

摘要翻译： 一种装置包括具有支撑由供给线供电的装置的机器人手臂的机器人。 该装置包括紧固到机器人臂的至少一个引导元件，并且供应线通过至少一个引导元件可移动地保持抵靠机器人手臂的至少一个部分。 提供至少一个存储元件用于接收供应线条。 所述至少一个存储元件以供应线的增加的拉伸载荷将所述供应管线从所述供应管线释放释放，并且在所述供应管线的拉伸载荷减小的情况下将所述供应管线缩回到所述供应管线中。