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公开(公告)号:US20130085259A1
公开(公告)日:2013-04-04
申请号:US13422722
申请日:2012-03-16
申请人: Hazel H. Szeto , Kesheng Zhao , Hugh D. Robertson , Alex V. Birk
发明人: Hazel H. Szeto , Kesheng Zhao , Hugh D. Robertson , Alex V. Birk
IPC分类号: C07K17/00
CPC分类号: A61K47/48246 , A61K31/713 , A61K38/47 , A61K47/64 , A61K47/645 , C07K5/1016 , C07K5/1019 , C07K17/00 , C12N9/2471 , C12N9/96 , C12N15/113 , C12N15/87 , C12N2310/3513 , C12N2320/32 , C12Y302/01023
摘要: The invention relates to carrier complexes and methods for delivering molecules to cells. The carrier complexes comprises a molecule and an aromatic cationic peptide in accordance with the invention. In one embodiment, the method for delivering a molecule to a cell comprises contacting the cell with a carrier complex. In another embodiment, the method for delivering a molecule to a cell comprises contacting the cell with a molecule and an aromatic cationic peptide.
摘要翻译: 本发明涉及用于将分子递送至细胞的载体复合物和方法。 载体复合物包含根据本发明的分子和芳族阳离子肽。 在一个实施方案中,将分子递送至细胞的方法包括使细胞与载体复合物接触。 在另一个实施方案中,将分子递送至细胞的方法包括使细胞与分子和芳族阳离子肽接触。
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公开(公告)号:US07704954B2
公开(公告)日:2010-04-27
申请号:US10838135
申请日:2004-05-03
申请人: Hazel H. Szeto , Kesheng Zhao , Hugh D. Robertson , Alex V. Birk
发明人: Hazel H. Szeto , Kesheng Zhao , Hugh D. Robertson , Alex V. Birk
CPC分类号: A61K47/48246 , A61K31/713 , A61K38/47 , A61K47/64 , A61K47/645 , C07K5/1016 , C07K5/1019 , C07K17/00 , C12N9/2471 , C12N9/96 , C12N15/113 , C12N15/87 , C12N2310/3513 , C12N2320/32 , C12Y302/01023
摘要: The invention relates to carrier complexes and methods for delivering molecules to cells. The carrier complexes comprises a molecule and an aromatic cationic peptide in accordance with the invention. In one embodiment, the method for delivering a molecule to a cell comprises contacting the cell with a carrier complex. In another embodiment, the method for delivering a molecule to a cell comprises contacting the cell with a molecule and an aromatic cationic peptide.
摘要翻译: 本发明涉及用于将分子递送至细胞的载体复合物和方法。 载体复合物包含根据本发明的分子和芳族阳离子肽。 在一个实施方案中,将分子递送至细胞的方法包括使细胞与载体复合物接触。 在另一个实施方案中,将分子递送至细胞的方法包括使细胞与分子和芳族阳离子肽接触。
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3.
公开(公告)号:US20170035899A1
公开(公告)日:2017-02-09
申请号:US15067726
申请日:2016-03-11
申请人: Hazel H. Szeto , Kesheng Zhao , Hugh Robertson , Alex V. Birk
发明人: Hazel H. Szeto , Kesheng Zhao , Hugh Robertson , Alex V. Birk
IPC分类号: A61K47/48 , C07K5/107 , C12N9/38 , A61K31/713 , A61K38/47 , C12N9/96 , C07K5/11 , C12N15/113
摘要: The invention relates to carrier complexes and methods for delivering molecules to cells. The carrier complexes comprises a molecule and an aromatic cationic peptide in accordance with the invention. In one embodiment, the method for delivering a molecule to a cell comprises contacting the cell with a carrier complex. In another embodiment, the method for delivering a molecule to a cell comprises contacting the cell with a molecule and an aromatic cationic peptide.
摘要翻译: 本发明涉及用于将分子递送至细胞的载体复合物和方法。 载体复合物包含根据本发明的分子和芳族阳离子肽。 在一个实施方案中,将分子递送至细胞的方法包括使细胞与载体复合物接触。 在另一个实施方案中,将分子递送至细胞的方法包括使细胞与分子和芳族阳离子肽接触。
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公开(公告)号:US09315586B2
公开(公告)日:2016-04-19
申请号:US13422722
申请日:2012-03-16
申请人: Hazel Szeto , Kesheng Zhao , Hugh Robertson , Alex V. Birk
发明人: Hazel Szeto , Kesheng Zhao , Hugh Robertson , Alex V. Birk
CPC分类号: A61K47/48246 , A61K31/713 , A61K38/47 , A61K47/64 , A61K47/645 , C07K5/1016 , C07K5/1019 , C07K17/00 , C12N9/2471 , C12N9/96 , C12N15/113 , C12N15/87 , C12N2310/3513 , C12N2320/32 , C12Y302/01023
摘要: The invention relates to carrier complexes and methods for delivering molecules to cells. The carrier complexes comprises a molecule and an aromatic cationic peptide in accordance with the invention. In one embodiment, the method for delivering a molecule to a cell comprises contacting the cell with a carrier complex. In another embodiment, the method for delivering a molecule to a cell comprises contacting the cell with a molecule and an aromatic cationic peptide.
摘要翻译: 本发明涉及用于将分子递送至细胞的载体复合物和方法。 载体复合物包含根据本发明的分子和芳族阳离子肽。 在一个实施方案中,将分子递送至细胞的方法包括使细胞与载体复合物接触。 在另一个实施方案中,将分子递送至细胞的方法包括使细胞与分子和芳族阳离子肽接触。
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