公开(公告)号：US20100255996A1

公开(公告)日：2010-10-07

申请号：US12668242

申请日：2008-07-07

申请人： Heidi Emilia Saxell ,  Jochen Dietz ,  Sebastian Peer SMIDT ,  Cedric Dieleman

发明人： Heidi Emilia Saxell ,  Jochen Dietz ,  Sebastian Peer SMIDT ,  Cedric Dieleman

IPC分类号： A01N43/56 ,  C07D231/14

CPC分类号： C07D231/14

摘要： The present invention relates to a new crystalline form of 3-(Difluormethyl)-1-methyl-N-(3′,4′,5′-trifluor[1,1′-biphenyl]-2-yl)-1H-pyrazol-4-carboxamide. The invention also relates to processes for the production of this crystalline form and formulations for plant protection which contain the crystalline form of 3-(Difluormethyl)-1-methyl-N -(3′,4′,5′-trifluor[1,1′-biphenyl]-2-yl)-1H-pyrazol-4-carboxamide.

摘要翻译： 本发明涉及3-（二甲基甲基）-1-甲基-N-（3'，4'，5'-三氟[1,1'-联苯] -2-基）-1H-吡唑的新结晶形式 -4-甲酰胺。 本发明还涉及生产该结晶形式的方法和用于植物保护的制剂，其含有3-（二甲基甲基）-1-甲基-N-（3'，4'，5'-三氟[ 联苯] -2-基）-1H-吡唑-4-甲酰胺。

公开(公告)号：US20100256418A1

公开(公告)日：2010-10-07

申请号：US12726196

申请日：2010-03-17

申请人： Sebastian Peer SMIDT ,  Jochen Dietz ,  Michael Keil ,  Thomas Grote

发明人： Sebastian Peer SMIDT ,  Jochen Dietz ,  Michael Keil ,  Thomas Grote

IPC分类号： C07C205/04

CPC分类号： C07C201/12 ,  C07C209/68 ,  C07C211/52 ,  C07C205/12

摘要： A process for preparing substituted biphenyls of the formula I in which the substituents are defined as follows: X is fluorine or chlorine; R1 is nitro, amino or NHR3; R2 is cyano, nitro, halogen, C1-C6-alkyl, C1-C-6-alkenyl, C1-C6-alkynyl, C1-C6-alkoxy, C1-C6-haloalkyl, C1-C6-alkylcarbonyl or phenyl; R3 is C1-C4-alkyl, C1-C4-alkenyl or C1-C4-alkynyl; n is 1, 2 or 3, where in case that n is 2 or 3, the R.sup.2 radicals may also be different, which comprises reacting the compound of the formula II in which Hal is halogen and X and R1 are as defined above, in the presence of a base and of a palladium catalyst selected from the group of:3 a) palladium-triarylphosphine or -trialkylphosphine complex with palladium in the zero oxidation state, b) salt of palladium in the presence of triarylphospine or trialkylphosphine as a complex ligand or c) metallic palladium, optionally applied to support, in the presence of triarylphosphine or trialkylphosphine, in a solvent, with a diphenylborinic acid (III) in which R2 and n are as defined above, where the triarylphosphines or trialkylphosphines used may be substituted.

摘要翻译： 制备式I取代的联苯的方法，其中取代基定义如下：X是氟或氯; R1是硝基，氨基或NHR3; R2是氰基，硝基，卤素，C1-C6-烷基，C1-C6-6烯基，C1-C6-炔基，C1-C6-烷氧基，C1-C6-卤代烷基，C1-C6烷基羰基或苯基; R3是C1-C4-烷基，C1-C4-烯基或C1-C4-炔基; n为1,2或3，其中在n为2或3的情况下，R 2基团也可以不同，其包括使其中Hal为卤素且X和R 1的式II化合物与 在碱存在下和选自以下组中的钯催化剂存在下：a）钯 - 三芳基膦或三烷基膦配合物与钯在零氧化状态，b）钯在三芳基膦或三烷基膦存在下的盐 作为络合配体或c）金属钯，任选地在三芳基膦或三烷基膦存在下，在溶剂中与二苯基硼酸（III）反应，其中R 2和n如上所定义，其中使用三芳基膦或三烷基膦 可以被替代。