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116 条记录 (耗时 0.038 秒)

    Process for the preparation of hydroxycarboxanilides
    3.
    发明授权
    Process for the preparation of hydroxycarboxanilides 失效
    羟基羧酰苯胺的制备方法

    公开(公告)号：US5631403A

    公开(公告)日：1997-05-20

    申请号：US493272

    申请日：1995-06-21

    申请人： Andreas Dierdorf ,  Siegfried Planker ,  Theodor Papenfuhs

    发明人： Andreas Dierdorf ,  Siegfried Planker ,  Theodor Papenfuhs

    IPC分类号： C07C231/12 ,  C07C235/16 ,  C07C253/30 ,  C07C233/05 ,  C07C233/88

    CPC分类号： C07C235/16 ,  C07C231/12 ,  C07C253/30

    摘要： The present invention relates to a process for the preparation of hydroxycarboxanilides of the formula (1) ##STR1## in which R.sup.1 and R.sup.2 are identical or different and are hydrogen, halogen, a nitro group, a cyano group, a straight-chain or branched alkyl, alkenyl, alkynyl or alkoxy group having 1 to 12 carbon atoms, an aralkyl group having 7 to 12 carbon atoms, a cycloalkyl group having 6 to 12 carbon atoms or an aryl group having 6 to 12 carbon atoms, R.sup.3 is hydrogen or a straight-chain or branched alkyl group having 1 to 12 carbon atoms and n is an integer from 1 to 12, by reacting a halocarboxanilide of the formula (2) ##STR2## in which R.sup.1, R.sup.2, R.sup.3 and n have the same meaning as in formula (1) and Hal is chlorine, bromine or iodine, with a basic compound in a solvent mixture comprising water and one or more polar aprotic solvents at a temperature of 40.degree. to 180.degree. C.

    摘要翻译： 本发明涉及制备式（1）的羟基羧酰苯胺的方法，其中R 1和R 2相同或不同，为氢，卤素，硝基，氰基， 具有1至12个碳原子的直链或支链烷基，烯基，炔基或烷氧基，具有7至12个碳原子的芳烷基，具有6至12个碳原子的环烷基或具有6至12个碳原子的芳基，R3是 氢或具有1至12个碳原子的直链或支链烷基，n为1至12的整数，通过使式（2）的卤代甲酰苯胺（2）反应，其中R 1，R 2，R 3和 n具有与式（1）中相同的含义，Hal是氯，溴或碘，在含有水和一种或多种极性非质子溶剂的溶剂混合物中，在40至180℃的温度下使用碱性化合物。

    Process for the preparation of 3,4,6-trifluorophthalic acid and the anhydride thereof
    8.
    发明授权
    Process for the preparation of 3,4,6-trifluorophthalic acid and the anhydride thereof 失效
    制备3,4,6-三氟乙酸及其无水物的方法

    公开(公告)号：US5200556A

    公开(公告)日：1993-04-06

    申请号：US887182

    申请日：1992-05-21

    申请人： Theodor Papenfuhs ,  Ralf Pfirmann

    发明人： Theodor Papenfuhs ,  Ralf Pfirmann

    IPC分类号： C07C51/083 ,  C07C51/377 ,  C07C51/567 ,  C07C63/68 ,  C07D307/89

    CPC分类号： C07C51/377 ,  C07C51/567

    摘要： Process for the preparation of 3,4,6-tetrafluorophthalic acid of the formula (1) ##STR1## or the anhydride thereof in good yields and in an advantageous manner, by dehalogenating tetrafluorophthalic anhydride of the formula (2) ##STR2## or tetrafluorophthalic acid in aqueous-alkaline medium using zinc at temperatures of approximately 20.degree. C. to approximately 160.degree. C. and, if appropriate, converting the resulting 3,4,6-trifluorophthalic acid into the anhydride in a known manner by dehydrating it.

    摘要翻译： 通过使式（2）的四氟邻苯二甲酸脱卤，以良好的产率和有利的方式制备式（1）的3,4,6-四氟邻苯二甲酸（1）或其酸酐的方法

    Process for the preparation of hydroxyethylsulfonylnitro- and hydroxyethylsulfonylamino-benzoic acids
    9.
    发明授权
    Process for the preparation of hydroxyethylsulfonylnitro- and hydroxyethylsulfonylamino-benzoic acids 失效
    羟基乙烯基硝基和羟基乙烯基亚氨基苯甲酸的制备方法

    公开(公告)号：US5101069A

    公开(公告)日：1992-03-31

    申请号：US550179

    申请日：1990-08-03

    申请人： Theodor Papenfuhs

    发明人： Theodor Papenfuhs

    IPC分类号： C07C313/00 ,  C07C67/00 ,  C07C315/02 ,  C07C317/44 ,  C07C317/48

    CPC分类号： C07C317/44

    摘要： A process for the preparation of compounds of the formula (5) ##STR1## in which R denotes a hydrogen or oxygen atom and the --N(R).sub.2 group and the hydroxyethylsulfonyl group are in the ortho- or para-position relative to one another by converting 1 mol of a halonitrobenzoic acid of the formula (2) ##STR2## in which X denotes a fluorine, chlorine, bromine or iodine atom and the nitro group and the halogen atom are in the ortho- or para-position relative to one another, with at least 1 mol of mercaptoethanol in an aqueous solution or suspension or in an organic solvent in the presence of an acid-binding agent at temperatures from about 20.degree. to about 100.degree. C., to the corresponding hydroxyethylmercaptonitrobenzoic acid of the formula (3) ##STR3## oxidizing these acids in a manner known per se to the corresponding hydroxyethylsulfonylnitrobenzoic acids of the formula (5) (R=0) mentioned and reducing the latter, if necessary, in a manner known per se to the corresponding hydroxyethylsulfonylaminobenzoic acids of the general formula (4) ##STR4## in which the amino and hydroxyethylsulfonyl group are in the ortho- or para-position relative to one another.

    Single-vessel process for preparing 2-acetaminonaphthalene-6-sulfonic acid of high purity
    10.
    发明授权
    Single-vessel process for preparing 2-acetaminonaphthalene-6-sulfonic acid of high purity 失效
    用于制备高纯度2-乙酰氨基萘-6-磺酸的单容器方法

    公开(公告)号：US4908478A

    公开(公告)日：1990-03-13

    申请号：US271376

    申请日：1988-11-10

    申请人： Otto Arndt ,  Theodor Papenfuhs

    发明人： Otto Arndt ,  Theodor Papenfuhs

    IPC分类号： B01J27/00 ,  C07C67/00 ,  C07C301/00 ,  C07C303/06 ,  C07C303/22 ,  C07C309/51

    CPC分类号： C07C309/51

    摘要： A single-vessel process for preparing 2-acetaminonaphthalene-6-sulfonic acid of high purity by sulfonating 2-hydroxynaphthalene with concentrated sulfuric acid, converting the 2-hydroxynaphthalenesulfonic acid formed with ammonia in the presence of ammonium hydrogensulfite into 2-amino-naphthalene-6-sulfonic acid (Bucherer reaction) and N-acetylating the latter to give 2-acetaminonaphthalene-6-sulfonic acid, which comprises, after diluting the sulfonating melt with water, substantially removing any impurities still present in the resulting aqueous solution of 2-hydroxynaphthalene-6-sulfonic acid, in particular 2-hydroxynaphthalene, by extraction with toluene or xylene and/or clarification using active carbon.

    摘要翻译： 通过用浓硫酸磺化2-羟基萘来制备高纯度2-乙酰氨基萘-6-磺酸的单容器方法，将在亚硫酸氢铵存在下由氨形成的2-羟基萘磺酸转化为2-氨基 - 萘 - 6-磺酸（Bucherer反应）和N-乙酰化后，得到2-乙酰氨基萘-6-磺酸，其包括在用水稀释磺化熔体之后，基本上除去所得到的2- 羟基萘-6-磺酸，特别是2-羟基萘，通过用甲苯或二甲苯萃取和/或使用活性炭澄清。