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1.发明申请DPP-IV INHIBITOR INCLUDING BETA-AMINO GROUP, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR PREVENTING AND TREATING DIABETES OR OBESITY 有权DPP-IV抑制剂，其包括氨基甲酰胺组，其制备方法和含有该组合物的预防和治疗糖尿病或肥胖的药物组合物公开(公告)号：US20100120790A1
公开(公告)日：2010-05-13
申请号：US12596281
申请日：2008-04-18
申请人： Heung Jae Kim , Woo Young Kwak , Chang Yell Shin , Hadong Kim , Jong Pil Min , Kyung Jin Park , Jae Young Lee , Song-Hyen Choi , Tae Hyun Yoon , Hae-Sun Kim , Ji Myung Jang , Mi-Kyung Kim , Moon-Ho Son , Soon Hoe Kim , Moohi Yoo
发明人： Heung Jae Kim , Woo Young Kwak , Chang Yell Shin , Hadong Kim , Jong Pil Min , Kyung Jin Park , Jae Young Lee , Song-Hyen Choi , Tae Hyun Yoon , Hae-Sun Kim , Ji Myung Jang , Mi-Kyung Kim , Moon-Ho Son , Soon Hoe Kim , Moohi Yoo
IPC分类号： A61K31/495 , C07D241/04 , A61P3/10 , A61P3/04
CPC分类号： C07D241/08
摘要： The present invention provides a novel heterocyclic compound containing a beta-amino group, a method for preparing the same, and a pharmaceutical composition comprising the same heterocyclic compound or a pharmaceutically acceptable salt thereof as an active ingredient. The heterocyclic compound of the present invention exhibits excellent DPP-IV inhibitory activity and bioavailability and therefore can be useful for the prophylaxis or treatment of DPP-IV-related diseases such as diabetes or obesity.
摘要翻译： 本发明提供了含有β-氨基的新型杂环化合物，其制备方法以及含有相同杂环化合物或其药学上可接受的盐作为有效成分的药物组合物。 本发明的杂环化合物显示优异的DPP-IV抑制活性和生物利用度，因此可用于预防或治疗DPP-IV相关疾病如糖尿病或肥胖症。
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2.发明授权DPP-IV inhibitor including beta-amino group, preparation method thereof and pharmaceutical composition containing the same for preventing and treating diabetes or obesity 有权DPP-IV抑制剂包括β-氨基，其制备方法和含有其的药物组合物用于预防和治疗糖尿病或肥胖症公开(公告)号：US08030315B2
公开(公告)日：2011-10-04
申请号：US12596281
申请日：2008-04-18
申请人： Heung Jae Kim , Woo Young Kwak , Chang Yell Shin , Hadong Kim , Jong Pil Min , Kyung Jin Park , Jae Young Lee , Song-Hyen Choi , Tae Hyun Yoon , Hae-Sun Kim , Ji Myun Jang , Mi-Kyung Kim , Moon-Ho Son , Soon Hoe Kim , Moohi Yoo
发明人： Heung Jae Kim , Woo Young Kwak , Chang Yell Shin , Hadong Kim , Jong Pil Min , Kyung Jin Park , Jae Young Lee , Song-Hyen Choi , Tae Hyun Yoon , Hae-Sun Kim , Ji Myun Jang , Mi-Kyung Kim , Moon-Ho Son , Soon Hoe Kim , Moohi Yoo
IPC分类号： A61K31/4965 , C07D241/04
CPC分类号： C07D241/08
摘要： The present invention provides a novel heterocyclic compound containing a beta-amino group, a method for preparing the same, and a pharmaceutical composition comprising the same heterocyclic compound or a pharmaceutically acceptable salt thereof as an active ingredient. The heterocyclic compound of the present invention exhibits excellent DPP-IV inhibitory activity and bioavailability and therefore can be useful for the prophylaxis or treatment of DPP-IV-related diseases such as diabetes or obesity.
摘要翻译： 本发明提供了含有β-氨基的新型杂环化合物，其制备方法以及含有相同杂环化合物或其药学上可接受的盐作为有效成分的药物组合物。 本发明的杂环化合物显示优异的DPP-IV抑制活性和生物利用度，因此可用于预防或治疗DPP-IV相关疾病如糖尿病或肥胖症。
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3.发明授权Pharmaceutical composition for prevention and treatment of diabetes or obesity comprising a compound that inhibits activity of dipeptidyl peptidase-IV, and other antidiabetic or antiobesity agents as active ingredients 有权用于预防和治疗糖尿病或肥胖症的药物组合物，其包含抑制二肽基肽酶-IV的活性的化合物和其它抗糖尿病或抗肥胖剂作为活性成分公开(公告)号：US08440669B2
公开(公告)日：2013-05-14
申请号：US13124150
申请日：2009-10-16
申请人： Chang Yell Shin , Song-Hyen Choi , Yu Na Chae , Eun Kyoung Yang , Gook Jun Ahn , Moon-Ho Son , Heung Jae Kim , Woo Young Kwak , Jong Pil Min , Tae Hyun Yoon , Soon Hoe Kim , Moohi Yoo
发明人： Chang Yell Shin , Song-Hyen Choi , Yu Na Chae , Eun Kyoung Yang , Gook Jun Ahn , Moon-Ho Son , Heung Jae Kim , Woo Young Kwak , Jong Pil Min , Tae Hyun Yoon , Soon Hoe Kim , Moohi Yoo
IPC分类号： A01N43/60 , A61K31/50 , A61K31/497
CPC分类号： A61K45/06 , A61K9/0019 , A61K9/145 , A61K9/2059 , A61K31/155 , A61K31/4439 , A61K31/495 , A61K31/5377 , A61K31/64 , A61K31/7028 , A61K47/02 , Y02P20/582 , A61K2300/00
摘要： The present invention relates to a pharmaceutical composition for the prevention and treatment of diabetes or obesity comprising as active ingredients a compound which inhibits the activity of dipeptidyl peptidase-IV (DPP-IV), a pharmaceutically acceptable salt thereof, a hydrate thereof, or a solvate thereof, and one or more other antidiabetic or antiobesity agents. The pharmaceutical composition exhibits excellent glucose tolerance and may be useful in the prevention and treatment of diabetes, obesity, and the like by effectively inhibiting blood glucose levels and reducing fat mass.
摘要翻译： 本发明涉及用于预防和治疗糖尿病或肥胖症的药物组合物，其包含抑制二肽基肽酶-IV（DPP-IV）的活性的化合物，其药学上可接受的盐，其水合物或 其一种或多种其它抗糖尿病或抗肥胖剂。 药物组合物表现出优异的葡萄糖耐量，可有效抑制血糖水平和降低脂肪量，可用于预防和治疗糖尿病，肥胖症等。
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4.发明申请Pharmaceutical Composition for Prevention and Treatment of Diabetes or Obesity Comprising a Compound that Inhibits Activity of Dipeptidyl Peptidase-IV, and other Antidiabetic or Antiobesity Agents as Active Ingredients 有权用于预防和治疗糖尿病或肥胖症的药物组合物，其包含抑制二肽基肽酶-IV和其它抗糖尿病或抗肥胖剂作为活性成分的活性的化合物公开(公告)号：US20110201624A1
公开(公告)日：2011-08-18
申请号：US13124150
申请日：2009-10-16
申请人： Chang Yell Shin , Song-Hyen Choi , Yu Na Chae , Eun Kyoung Yang , Gook Jun Ahn , Moon-Ho Son , Heung Jae Kim , Woo Young Kwak , Jong Pil Min , Tae Hyun Yoon , Soon Hoe Kim , Moohi Yoo
发明人： Chang Yell Shin , Song-Hyen Choi , Yu Na Chae , Eun Kyoung Yang , Gook Jun Ahn , Moon-Ho Son , Heung Jae Kim , Woo Young Kwak , Jong Pil Min , Tae Hyun Yoon , Soon Hoe Kim , Moohi Yoo
IPC分类号： A61K31/4965 , A61P3/04 , A61P3/10
CPC分类号： A61K45/06 , A61K9/0019 , A61K9/145 , A61K9/2059 , A61K31/155 , A61K31/4439 , A61K31/495 , A61K31/5377 , A61K31/64 , A61K31/7028 , A61K47/02 , Y02P20/582 , A61K2300/00
摘要： The present invention relates to a pharmaceutical composition for the prevention and treatment of diabetes or obesity comprising as active ingredients a compound which inhibits the activity of dipeptidyl peptidase-IV (DPP-IV), a pharmaceutically acceptable salt thereof, a hydrate thereof, or a solvate thereof, and one or more other antidiabetic or antiobesity agents. The pharmaceutical composition exhibits excellent glucose tolerance and may be useful in the prevention and treatment of diabetes, obesity, and the like by effectively inhibiting blood glucose levels and reducing fat mass.
摘要翻译： 本发明涉及用于预防和治疗糖尿病或肥胖症的药物组合物，其包含抑制二肽基肽酶-IV（DPP-IV）的活性的化合物，其药学上可接受的盐，其水合物或 其一种或多种其它抗糖尿病或抗肥胖剂。 药物组合物表现出优异的葡萄糖耐量，可有效抑制血糖水平和降低脂肪量，可用于预防和治疗糖尿病，肥胖症等。
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5.发明授权公开(公告)号：US08598347B2
公开(公告)日：2013-12-03
申请号：US13260179
申请日：2010-03-30
申请人： Woo Young Kwak , Heung Jae Kim , Jong Pil Min , Tae Hyun Yoon , Hyun Joo Shim , Moohi Yoo
发明人： Woo Young Kwak , Heung Jae Kim , Jong Pil Min , Tae Hyun Yoon , Hyun Joo Shim , Moohi Yoo
IPC分类号： C07D241/08 , C07C323/58 , C07C227/10
CPC分类号： C07D203/18 , C07C269/06 , C07D265/32 , Y02P20/55 , C07C271/22
摘要： The present invention relates to an improved method for manufacturing dipeptidyl peptidase-IV inhibitor and intermediate. The present invention allows reduction of production costs by reacting low cost reagents, improves yield and is adaptable for mass production.
摘要翻译： 本发明涉及二肽基肽酶-IV抑制剂和中间体的改进方法。 本发明通过使低成本试剂反应，可以提高生产成本，提高产量，适用于批量生产。
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6.发明申请METHOD FOR MANUFACTURING DIPEPTIDYL PEPTIDASE-IV INHIBITOR AND INTERMEDIATE 有权制备DIPEPTIDYP肽酶IV抑制剂和中间体的方法公开(公告)号：US20120016126A1
公开(公告)日：2012-01-19
申请号：US13260179
申请日：2010-03-30
申请人： Woo Young Kwak , Heung Jae Kim , Jong Pil Min , Tae Hyun Yoon , Hyun Joo Shim , Moohi Yoo
发明人： Woo Young Kwak , Heung Jae Kim , Jong Pil Min , Tae Hyun Yoon , Hyun Joo Shim , Moohi Yoo
IPC分类号： C07D241/08 , C07C323/58 , C07C227/10
CPC分类号： C07D203/18 , C07C269/06 , C07D265/32 , Y02P20/55 , C07C271/22
摘要： The present invention relates to an improved method for manufacturing dipeptidyl peptidase-IV inhibitor and intermediate. The present invention allows reduction of production costs by reacting low cost reagents, improves yield and is adaptable for mass production.
摘要翻译： 本发明涉及二肽基肽酶-IV抑制剂和中间体的改进方法。 本发明通过使低成本试剂反应，可以提高生产成本，提高产量，适用于批量生产。
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7.发明申请公开(公告)号：US20120016125A1
公开(公告)日：2012-01-19
申请号：US13259699
申请日：2010-03-30
申请人： Woo Young Kwak , Heung Jae Kim , Jong Pil Min , Tae Hyun Yoon , Moohi Yoo , Geun Gho Lim , Sun Ki Chang
发明人： Woo Young Kwak , Heung Jae Kim , Jong Pil Min , Tae Hyun Yoon , Moohi Yoo , Geun Gho Lim , Sun Ki Chang
IPC分类号： C07D241/08 , C07C255/35 , C07C311/19 , C07D203/06 , C07C227/12 , C07C269/04
CPC分类号： C07D241/08 , C07C29/106 , C07C29/36 , C07C227/02 , C07C241/00 , C07C247/10 , C07C253/00 , C07C255/42 , C07C255/44 , C07C269/06 , C07C271/22 , C07D203/08 , C07D203/10 , C07D203/18 , Y02P20/55 , C07C33/46
摘要： The present invention relates to an improved method for preparing dipeptidyl peptidase-IV inhibitor and intermediate. The present invention is able to reduce preparation costs by using low cost reagents on reaction and is able to be used in mass production by improving yield.
摘要翻译： 本发明涉及二肽基肽酶-IV抑制剂和中间体的改进方法。 本发明能够通过在反应中使用低成本试剂来降低制备成本，并且能够通过提高产率而用于批量生产。
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8.发明申请公开(公告)号：US20080140915A1
公开(公告)日：2008-06-12
申请号：US11694394
申请日：2007-03-30
申请人： Won-Chul Ju , Tae Hyun Yoon
发明人： Won-Chul Ju , Tae Hyun Yoon
IPC分类号： G06F12/02
CPC分类号： G06F12/0246 , G06F13/385 , G06F2212/1036 , G06F2212/7211 , G11C16/349
摘要： A memory card system and method of transmitting lifetime information thereof includes a host generating a lifetime information command, and a memory card including a memory to store data provided from the host, the memory card providing the host with lifetime information of the memory in response to the lifetime information command of the host.
摘要翻译： 存储卡系统和发送生命周期信息的方法包括生成生命周期信息命令的主机和包括存储器的存储卡，存储器存储从主机提供的数据，存储卡向主机提供响应于存储器的寿命信息 主机的生命周期信息命令。
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