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11 条记录 (耗时 0.019 秒)

    Method for discriminating between prostatic cancer and benign prostatic hyperplasia
    3.
    发明授权
    Method for discriminating between prostatic cancer and benign prostatic hyperplasia 有权
    鉴别前列腺癌与良性前列腺增生的方法

    公开(公告)号：US08030085B2

    公开(公告)日：2011-10-04

    申请号：US12216202

    申请日：2008-07-01

    申请人： Junko Amano ,  Kiyoko Hirano ,  Ichiro Sugimoto

    发明人： Junko Amano ,  Kiyoko Hirano ,  Ichiro Sugimoto

    IPC分类号： G01N33/00 ,  G01N30/00

    CPC分类号： G01N33/57434 ,  G01N33/6893 ,  G01N2800/342

    摘要： The present invention provides a method for accurately discriminating between prostate carcinoma and benign prostatic hyperplasia based on a glycan structure of prostate specific antigen (PSA). The method of the present invention includes the steps of: purifying PSA from a sample derived from a subject; preparing a PSA derivative from the PSA; labeling the PSA derivative; and analyzing the labeled PSA derivative by the mass spectrometry method, in which the subject is identified as having prostate carcinoma when the ratio of the signal intensity of fucose-unbound glycan to the signal intensity of fucose-bound glycan in the labeled PSA derivative is greater than 1.0, and identified as having benign prostatic hyperplasia when the ratio is 1.0 or less.

    摘要翻译： 本发明提供了一种基于前列腺特异性抗原（PSA）的聚糖结构来准确区分前列腺癌和良性前列腺增生的方法。 本发明的方法包括以下步骤：从源自受试者的样品中纯化PSA; 从PSA制备PSA衍生物; 标记PSA衍生物; 并且通过质谱法分析标记的PSA衍生物，其中当标记的PSA衍生物中岩藻糖未结合的聚糖的信号强度与岩藻糖结合的聚糖的信号强度的比例更大时，被摄体被鉴定为具有前列腺癌 比例为1.0以上时，鉴定为具有良性前列腺增生。

    Biodegradable plastic molded article
    4.
    发明授权
    Biodegradable plastic molded article 有权
    生物降解塑料成型品

    公开(公告)号：US06350531B1

    公开(公告)日：2002-02-26

    申请号：US09622755

    申请日：2000-10-30

    申请人： Ichiro Sugimoto

    发明人： Ichiro Sugimoto

    IPC分类号： B32B1500

    CPC分类号： C08L67/02 ,  C05G3/0052 ,  C08K3/00 ,  C08L67/04 ,  C08L2201/06 ,  Y10T428/2982 ,  Y10T428/31975 ,  C08L2666/26

    摘要： A biodegradable plastic article molded of a mixture comprising the following components: (A) a biodegradable plastic at 98 to 59% by weight, (B) a dry powder of a water-swelling fiber at 1 to 40% by weight, and (C) a fertilizer powder at 1 to 40% by weight (wherein the sum of (B) and (C) is from 2 to 41% by weight). This biodegradable plastic article can improve biodegradability of the biodegradable plastics and make it possible to regulate the rate of biodegradation thereof.

    摘要翻译： 一种由包含以下组分的混合物模制的可生物降解的塑料制品：（A）98至59重量％的生物可降解塑料，（B）1至40重量％的水溶胀纤维的干粉和（C ）1〜40重量％的肥料粉末（其中（B）和（C）的总和为2〜41重量％）。 该可生物降解的塑料制品可以改善可生物降解塑料的生物降解性，并且可以调节其生物降解速率。

    Physical random number generation device
    5.
    发明授权
    Physical random number generation device 失效
    物理随机数生成装置

    公开(公告)号：US08583713B2

    公开(公告)日：2013-11-12

    申请号：US12845044

    申请日：2010-07-28

    申请人： Ichiro Sugimoto ,  Yoshiyuki Oinuma

    发明人： Ichiro Sugimoto ,  Yoshiyuki Oinuma

    IPC分类号： G06F7/58

    CPC分类号： G06F7/588

    摘要： A physical random number generation device includes a physical random number generation source which generates a white noise, an AD conversion module which inputs the white noise for conversion to a physical prime random number as digital data, a physical prime random number sequence generation module which inputs two or more physical prime random numbers to generate a physical prime random number sequence, a white noise array generation module for inputting the physical prime random number sequence and for generating a white noise array, a white noise composition module for generating multiple physical random numbers from the input white noise array, and an interface for externally outputting the generated physical random numbers as physical random number data. With this arrangement, multiple physical random numbers are generated at high speeds from the physical prime random number(s) taken out of the physical random number generation source as digital data.

    摘要翻译： 物理随机数生成装置包括产生白噪声的物理随机数产生源，将用于转换的白噪声输入到物理素数随机数的AD转换模块作为数字数据，物理素数随机数序列生成模块，其输入 用于生成物理素数随机数的两个或多个物理素数随机数，用于输入物理素数随机数序列并用于产生白噪声阵列的白噪声阵列产生模块，用于从 输入白噪声阵列，以及用于从外部输出生成的物理随机数作为物理随机数数据的接口。 利用这种安排，从作为数字数据的物理随机数生成源中取出的物理素数随机数以高速生成多个物理随机数。

    Electrically conductive plastic molded article and method of production thereof
    6.
    发明授权
    Electrically conductive plastic molded article and method of production thereof 失效
    导电性塑料成型体及其制造方法

    公开(公告)号：US06380282B1

    公开(公告)日：2002-04-30

    申请号：US09381786

    申请日：1999-12-13

    申请人： Ichiro Sugimoto

    发明人： Ichiro Sugimoto

    IPC分类号： C08L102

    CPC分类号： H01B1/20 ,  H01B1/24

    摘要： A method of producing an electrically conductive plastic molded article comprising blending 1 to 40 we. % of content shell fiber powder obtained by dry compressing a fiber contained in the mesocarp of the coconut fruit and processing the resulting fiber mass to 98 to 59 we. % of a biodegradable plastic or a non-biodegradable plastic, and adding 1 to 20 we. % of an electrically conductive additive. A molded article eliminating electrostatic troubles due to electrical chargeability, and improving biodegradable plastic is used, can be obtained.

    摘要翻译： 一种制造导电塑料模制品的方法，包括将1至40混合。 通过干燥压缩椰子果实的中果皮中的纤维获得的含量的壳纤维粉末的％，并将所得纤维质量加工至98〜59。 ％的可生物降解塑料或不可生物降解的塑料，并加1至20我们。 ％的导电添加剂。 可以得到消除由于充电性导致的静电麻烦，改善生物降解性塑料的成型品。

    Biodegradable plastic product made from coconut husk fiber powder mixture
    7.
    发明授权
    Biodegradable plastic product made from coconut husk fiber powder mixture 失效
    由椰子壳纤维粉末混合物制成的可生物降解塑料制品

    公开(公告)号：US6083621A

    公开(公告)日：2000-07-04

    申请号：US24678

    申请日：1998-02-17

    申请人： Ichiro Sugimoto

    发明人： Ichiro Sugimoto

    IPC分类号： C08L67/02 ,  D02G3/00 ,  C08J3/00 ,  C08K5/00 ,  C08J1/00 ,  C08J6/00

    CPC分类号： C08L67/02 ,  Y10T428/2933 ,  Y10T428/2938

    摘要： Processed plant fine fibers such as those from the mesocarp of a coconut together are blended with a biodegradable plastic to produce a biodegradable plastic product that can be further made into other items. Plastics thus made from coconut husk fine fiber powder will return to the environment after disposal much more rapidly than those without coconut husk fine fiber powder. In the process, a dry compressed plant fine fiber powder is created from fine fibers of the coconut mesocarp. An example product created from this raw material is composed of 10 to 40% by weight of dry coconut husk powder mixed with environmentally degradable plastic. Environmentally non-degradable plastic may be added to the dry powder as a biodegradation rate modulator to create a modified raw material with a modified biodegradation rate. Plastic additives, standard in the industry, can be added to achieve additional desired properties. For example, a surface active agent may be added in order to increase the degree of processability; a colorant may be added to increase marketability; pesticides may be added as needed in order to protect the product or the soil in which the product is disposed from insects; and/or polymerization modifiers such as cross-linkers, monomer derivatives, heteromonomers, curing agents, etc. may be utilized to vary the properties of the base plastic.

    摘要翻译： 将处理过的植物细纤维如来自椰子的中果皮的细纤维与可生物降解的塑料共混以生产可生物降解的塑料制品，其可以进一步制成其它物品。 由椰子壳细纤维粉制成的塑料，比没有椰壳细纤维粉的处理要快得多。 在此过程中，由椰子中果皮的细纤维产生干压缩植物细纤维粉末。 由该原料制成的示例性产品由10至40重量％的与环境可降解塑料混合的干椰壳粉末组成。 可以将环境不可降解塑料作为生物降解速率调节剂添加到干粉中以产生具有改良的生物降解速率的改性原料。 可以加入行业标准的塑料添加剂以达到额外的所需性能。 例如，可以加入表面活性剂以增加可加工性的程度; 可以添加着色剂以增加市场性; 可根据需要添加农药，以保护产品或产品从昆虫中排出的土壤; 和/或聚合改性剂如交联剂，单体衍生物，异型单体，固化剂等可用于改变基础塑料的性质。

    Electric toothbrush
    8.
    发明申请
    Electric toothbrush 审中-公开
    电动牙刷

    公开(公告)号：US20090056043A1

    公开(公告)日：2009-03-05

    申请号：US11665055

    申请日：2005-10-13

    申请人： Ichiro Sugimoto

    发明人： Ichiro Sugimoto

    IPC分类号： A46B9/04 ,  A46B13/02

    CPC分类号： A61C17/02 ,  A61C15/046 ,  A61C15/047 ,  A61C17/022 ,  A61C17/32

    摘要： It is desired to realize designing of a light, compact body and improved brushing effect and massage effect without causing any inconvenience, and to prevent the tip of a brush formed by a bristle bundle from remaining curled.A flexible diaphragm 13 which is displaced together with a reciprocative base 10 of a brush 9 is provided between a body space 2 and a brush guide passage 6. An air introduction hole 15 having a valve 14 which opens only to the inside is formed in a midpoint of the brush guide passage 6. When the diaphragm 13 is displaced toward the body space 2 with the reciprocation motion of the base 10, air is introduced through the air introduction hole 15 into the brush guide passage 6, which is now under negative pressure. When the diaphragm 13 is displaced toward the brush guide passage 6, the introduced air is compressed and is ejected from the opening 6a at the tip. Thus, the body can be designed lightly and compactly, and the brushing effect and the massage effect are improved without causing inconvenience.

    摘要翻译： 希望实现轻，紧凑的身体的设计，并且改善刷牙效果和按摩效果，而不引起任何不便，并且防止由刷毛束形成的刷子的尖端保持卷曲。 在主体空间2和电刷引导通道6之间设置与电刷9的往复运动基座10一起移动的柔性隔膜13.具有仅向内侧开口的阀14的空气导入孔15形成为 刷子引导通道6的中点。当隔膜13随着基座10的往复运动而朝向主体空间2移动时，空气通过空气引入孔15被引入到当前处于负压下的电刷引导通道6中 。 当隔膜13朝向刷引导通道6移动时，引入的空气被压缩并从尖端处的开口6a排出。 因此，身体可以轻轻紧凑地设计，并且改善刷牙效果和按摩效果而不会引起不便。

    Method for discriminating between prostatic cancer and benign prostatic hyperplasia
    9.
    发明申请
    Method for discriminating between prostatic cancer and benign prostatic hyperplasia 有权
    鉴别前列腺癌与良性前列腺增生的方法

    公开(公告)号：US20090023220A1

    公开(公告)日：2009-01-22

    申请号：US12216202

    申请日：2008-07-01

    申请人： Junko Amano ,  Kiyoko Hirano ,  Ichiro Sugimoto

    发明人： Junko Amano ,  Kiyoko Hirano ,  Ichiro Sugimoto

    IPC分类号： G01N33/68 ,  G01N30/00

    CPC分类号： G01N33/57434 ,  G01N33/6893 ,  G01N2800/342

    摘要： The present invention provides a method for accurately discriminating between prostate carcinoma and benign prostatic hyperplasia based on a glycan structure of prostate specific antigen (PSA). The method of the present invention includes the steps of: purifying PSA from a sample derived from a subject; preparing a PSA derivative from the PSA; labeling the PSA derivative; and analyzing the labeled PSA derivative by the mass spectrometry method, in which the subject is identified as having prostate carcinoma when the ratio of the signal intensity of fucose-unbound glycan to the signal intensity of fucose-bound glycan in the labeled PSA derivative is greater than 1.0, and identified as having benign prostatic hyperplasia when the ratio is 1.0 or less.

    摘要翻译： 本发明提供了一种基于前列腺特异性抗原（PSA）的聚糖结构来准确区分前列腺癌和良性前列腺增生的方法。 本发明的方法包括以下步骤：从源自受试者的样品中纯化PSA; 从PSA制备PSA衍生物; 标记PSA衍生物; 并且通过质谱法分析标记的PSA衍生物，其中当标记的PSA衍生物中岩藻糖未结合的聚糖的信号强度与岩藻糖结合的聚糖的信号强度的比例更大时，被摄体被鉴定为具有前列腺癌 比例为1.0以上时，鉴定为具有良性前列腺增生。