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6 条记录 (耗时 0.023 秒)

    Method of detection and disease state management for renal diseases
    1.
    发明授权
    Method of detection and disease state management for renal diseases 失效
    肾脏疾病的检测和疾病状态管理方法

    公开(公告)号：US07109044B1

    公开(公告)日：2006-09-19

    申请号：US09786503

    申请日：1999-04-09

    申请人： Hiroshi Oda ,  Kosuke Seiki ,  Hiroshi Nakajima ,  Nobuyuki Sato ,  Yoshihiro Urade ,  Nobuhito Hirawa ,  Yoshio Uehara

    发明人： Hiroshi Oda ,  Kosuke Seiki ,  Hiroshi Nakajima ,  Nobuyuki Sato ,  Yoshihiro Urade ,  Nobuhito Hirawa ,  Yoshio Uehara

    IPC分类号： G01N33/53

    CPC分类号： G01N33/6893 ,  G01N33/573 ,  G01N33/70 ,  G01N33/88 ,  G01N2800/347 ,  Y10S436/811

    摘要： The present invention relates to a method of detection of an early-stage renal disease, comprising determining the concentration of human lipocalin-type prostaglandin D synthase in a body fluid sample taken from a subject and comparing the determined concentration with a reference value set by determining the concentrations of human lipocalin-type prostaglandin D synthase in body fluid samples taken from healthy subjects; and a method of disease state management for a renal disease, comprising determining the concentration of human lipocalin-type prostaglandin D synthase in a body fluid sample taken from a subject and evaluating the glomerular filtration ability of the subject from the determined concentration.

    摘要翻译： 本发明涉及一种早期肾病的检测方法，包括测定取自受试者的体液样品中人脂笼蛋白型前列腺素D合成酶的浓度，并将测定的浓度与通过确定 来自健康受试者的体液样品中人脂笼蛋白型前列腺素D合成酶的浓度; 以及肾病疾病状态管理方法，包括测定取自对象的体液样品中人脂质运载蛋白型前列腺素D合成酶的浓度，并根据测定的浓度评价受试者的肾小球滤过能力。

    Underdrainage pipe
    3.
    发明授权
    Underdrainage pipe 失效
    排水管

    公开(公告)号：US4182580A

    公开(公告)日：1980-01-08

    申请号：US887746

    申请日：1978-03-17

    申请人： Shozo Hieda ,  Yoshio Uehara ,  Minoru Inaba

    发明人： Shozo Hieda ,  Yoshio Uehara ,  Minoru Inaba

    IPC分类号： F16L9/06 ,  E02B11/00 ,  F16L11/12 ,  E02B13/00 ,  F16L11/11

    CPC分类号： E02B11/005

    摘要： An underdrainage pipe comprises a liquid-collecting pipe, protrusions on the liquid-collecting pipe, a filter layer around the liquid-collecting pipe and a liquid-conducting way, and the protrusions having at least one recess for each and the bottom portion of the recess not reaching the surface of the liquid-collecting pipe.

    摘要翻译： 排液管包括液体收集管，集液管上的突起，集液管周围的过滤层和导液方式，并且突起具有用于每个和底部的至少一个凹部 凹部未到达集液管的表面。

    Vascular protecting agent having salt-absorption inhibitory activity
    4.
    发明授权
    Vascular protecting agent having salt-absorption inhibitory activity 有权
    具有吸收盐抑制活性的血管保护剂

    公开(公告)号：US08569261B2

    公开(公告)日：2013-10-29

    申请号：US13219969

    申请日：2011-08-29

    申请人： Itsuki Murota ,  Yoshio Uehara

    发明人： Itsuki Murota ,  Yoshio Uehara

    IPC分类号： A61K31/715

    CPC分类号： A61K31/702 ,  A61K31/7016 ,  C12P19/00 ,  C12R1/38

    摘要： This invention provides a vascular protecting agent having salt-absorption inhibitory activity with the use of alginate oligosaccharide salt absorbed by the body via degradation to an oligosaccharide, so that a patient can easily and safely ingest such agent on a routine basis. A vascular protecting agent having salt-absorption inhibitory activity comprises, as an active ingredient, alginate oligosaccharide obtained by treating sodium alginate with a Pseudoalteromonas microorganism or a processed product thereof and/or a salt thereof.

    摘要翻译： 本发明提供一种具有吸收抑制活性的血管保护剂，其使用通过降解寡糖而被身体吸收的藻酸盐寡糖盐，使得患者可以以常规方式容易且安全地摄取该药剂。 具有盐吸收抑制活性的血管保护剂包含作为活性成分的藻酸钠寡糖，其通过用假微生物微生物或其加工产物和/或其盐处理海藻酸钠而获得。

    VASCULAR PROTECTING AGENT HAVING SALT-ABSORPTION INHIBITORY ACTIVITY
    5.
    发明申请
    VASCULAR PROTECTING AGENT HAVING SALT-ABSORPTION INHIBITORY ACTIVITY 有权
    具有盐吸收抑制活性的血管保护剂

    公开(公告)号：US20120058967A1

    公开(公告)日：2012-03-08

    申请号：US13219969

    申请日：2011-08-29

    申请人： Itsuki MUROTA ,  Yoshio Uehara

    发明人： Itsuki MUROTA ,  Yoshio Uehara

    IPC分类号： A61K31/715 ,  A61P13/12 ,  A61P9/00

    CPC分类号： A61K31/702 ,  A61K31/7016 ,  C12P19/00 ,  C12R1/38

    摘要： This invention provides a vascular protecting agent having salt-absorption inhibitory activity with the use of alginate oligosaccharide salt absorbed by the body via degradation to an oligosaccharide, so that a patient can easily and safely ingest such agent on a routine basis. A vascular protecting agent having salt-absorption inhibitory activity comprises, as an active ingredient, alginate oligosaccharide obtained by treating sodium alginate with a Pseudoalteromonas microorganism or a processed product thereof and/or a salt thereof.

    摘要翻译： 本发明提供一种具有吸收抑制活性的血管保护剂，其使用通过降解寡糖而被身体吸收的藻酸盐寡糖盐，使得患者可以以常规方式容易且安全地摄取该药剂。 具有盐吸收抑制活性的血管保护剂包含作为活性成分的藻酸钠寡糖，其通过用假微生物微生物或其加工产物和/或其盐处理海藻酸钠而获得。

    Pipe for underdraining
    6.
    发明授权
    Pipe for underdraining 失效
    排水管道

    公开(公告)号：US4182581A

    公开(公告)日：1980-01-08

    申请号：US887608

    申请日：1978-03-17

    申请人： Yoshio Uehara ,  Minoru Inaba ,  Noriyuki Ishii ,  Yoshihisa Kusumi

    发明人： Yoshio Uehara ,  Minoru Inaba ,  Noriyuki Ishii ,  Yoshihisa Kusumi

    IPC分类号： E02B11/00 ,  E02B13/00 ,  F16L11/11

    CPC分类号： E02B11/005

    摘要： A pipe for underdrainage comprises (1) a liquid-collecting pipe; (2) a plurality of discontinuous protrusions on the outer surface of the liquid-collecting pipe; (3) a filter layer capable of passing liquid while substantially excluding solids, the filter layer being disposed around the liquid-collecting pipe and contacting the top portions of the protrusions; and (4) a liquid-conducting way composed of a space communicating both in the longitudinal direction and in the peripheral direction of the liquid collecting pipe and defined by the protrusions, the outer surface of the liquid-collecting pipe and the inner surface of the filter layer.

    摘要翻译： 用于排污的管道包括（1）集液管; （2）在集液管的外表面上的多个不连续突起; （3）能够在基本上排除固体的同时通过液体的过滤层，所述过滤层设置在所述集液管周围并与所述突起的顶部接触; 和（4）由液体收集管的纵向方向和周向连通且由突出部限定的空间，集液管的外表面和液体收集管的内表面构成的导液方式 过滤层。