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公开(公告)号:US06172215B2
公开(公告)日:2001-01-09
申请号:US09230380
申请日:1999-07-12
申请人: Hiroyuki Keshi , Soji Eda , Hirotsugu Uehara , Keigo Nishida , Akio Matsuhisa
发明人: Hiroyuki Keshi , Soji Eda , Hirotsugu Uehara , Keigo Nishida , Akio Matsuhisa
IPC分类号: C07H2104
CPC分类号: C12Q1/689
摘要: DNA probes for detecting the presence of Helicobacter pylori are provided. These isolated, purified oligonucleotide probes are useful in assays for the specific detection of Helicobacter pylori because they specifically hybridize to the DNA of H. pylori.
摘要翻译: 提供了用于检测幽门螺杆菌存在的DNA探针。 这些分离的,纯化的寡核苷酸探针可用于特异性检测幽门螺杆菌的检测,因为它们与幽门螺杆菌的DNA特异性杂交。
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公开(公告)号:US20070059687A1
公开(公告)日:2007-03-15
申请号:US10479027
申请日:2002-05-27
申请人: Tsuneya Ohno , Akio Matsuhisa , Hiroyuki Keshi , Kanako Abe , Norihiko Sugimoto , Hiroshi Ueyama , Soji Eda , Hirotsugu Uehara , Takahisa Iwami , Seiji Yamamoto , Hiromasa Araki
发明人: Tsuneya Ohno , Akio Matsuhisa , Hiroyuki Keshi , Kanako Abe , Norihiko Sugimoto , Hiroshi Ueyama , Soji Eda , Hirotsugu Uehara , Takahisa Iwami , Seiji Yamamoto , Hiromasa Araki
CPC分类号: G01N33/5047 , C12Q1/6841 , C12Q1/689 , G01N33/5005
摘要: A digested phagocyte prepared by contacting in vitro a phagocyte with a foreign microorganism and isolating the phagocyte so contacted; a process for producing the same; and a process and a kit in which these are utilized are disclosed. An experimental model, which enables in vitro evaluation of a phagocytotic function of phagocytes, is provided.
摘要翻译: 通过体外将吞噬细胞与外来微生物接触并分离所接触的吞噬细胞制备的消化的吞噬细胞; 其制造方法; 并且公开了使用这些的方法和试剂盒。 提供了能够体外评估吞噬细胞吞噬功能的实验模型。
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公开(公告)号:US06660852B1
公开(公告)日:2003-12-09
申请号:US08809254
申请日:1997-05-16
申请人: Hiroyuki Keshi , Soji Eda , Hirotsugu Uehara , Hiroshi Ueyama , Akio Matsuhisa
发明人: Hiroyuki Keshi , Soji Eda , Hirotsugu Uehara , Hiroshi Ueyama , Akio Matsuhisa
IPC分类号: C12N1563
CPC分类号: C12Q1/689
摘要: A probe derived from bacteria of pneumonia, containing fragments of DNA which streptococcus pneumoniae essentially possesses, and useful for detecting and identifying causative bacteria of pneumonia is obtained by completely digesting the DNA with a restriction endonuclease PstI, followed by cloning into a suitable vector.
摘要翻译: 通过用限制性内切核酸酶PstI完全消化DNA,然后克隆到合适的载体中,获得含有肺炎链球菌基本上具有的DNA片段的可用于检测和鉴定肺炎的致病菌的肺炎细菌的探针。
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公开(公告)号:US5853998A
公开(公告)日:1998-12-29
申请号:US920828
申请日:1997-08-29
申请人: Tsuneya Ohno , Akio Matsuhisa , Hirotsugu Uehara , Soji Eda
发明人: Tsuneya Ohno , Akio Matsuhisa , Hirotsugu Uehara , Soji Eda
IPC分类号: C12N15/09 , C12N15/11 , C12Q1/68 , C12R1/01 , C12R1/19 , C12R1/22 , C12R1/385 , G01N33/53 , G01N33/566 , C07H21/04
CPC分类号: C12Q1/689 , C12Q2600/156
摘要: DNA probes for diagnosing infectious diseases involving Enterococcus faecalis and methods of using such probes are provided.
摘要翻译: 提供了用于诊断涉及粪肠球菌感染性疾病的DNA探针和使用这种探针的方法。
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公开(公告)号:US5798211A
公开(公告)日:1998-08-25
申请号:US921177
申请日:1997-08-29
申请人: Tsuneya Ohno , Akio Matsuhisa , Hirotsugu Uehara , Soji Eda
发明人: Tsuneya Ohno , Akio Matsuhisa , Hirotsugu Uehara , Soji Eda
IPC分类号: C12N15/09 , C12N15/11 , C12Q1/68 , C12R1/01 , C12R1/19 , C12R1/22 , C12R1/385 , G01N33/53 , G01N33/566 , C07H21/04
CPC分类号: C12Q1/689 , C12Q2600/156
摘要: DNA probes for diagnosing infectious diseases involving Pseudomonas aeruginosa and methods of using such probes are provided.
摘要翻译: 提供了用于诊断涉及铜绿假单胞菌感染性疾病的DNA探针和使用这种探针的方法。
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公开(公告)号:US5807673A
公开(公告)日:1998-09-15
申请号:US362577
申请日:1995-03-27
申请人: Tsuneya Ohno , Akio Matsuhisa , Hirotsugu Uehara , Soji Eda
发明人: Tsuneya Ohno , Akio Matsuhisa , Hirotsugu Uehara , Soji Eda
IPC分类号: C12N15/09 , C12N15/11 , C12Q1/68 , C12R1/01 , C12R1/19 , C12R1/22 , C12R1/385 , G01N33/53 , G01N33/566 , C07H21/04
CPC分类号: C12Q1/689 , C12Q2600/156
摘要: DNA probes for diagnosing infectious diseases involving Staphylococcus aureus and methods of using such probes are provided.
摘要翻译: PCT No.PCT / JP93 / 00936 Sec。 371日期:1995年3月27日 102(e)1995年3月27日PCT PCT 1993年7月7日PCT公布。 公开号WO94 / 01583 日期1994年1月20日提供了用于诊断涉及金黄色葡萄球菌感染性疾病的DNA探针和使用这种探针的方法。
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公开(公告)号:US5770375A
公开(公告)日:1998-06-23
申请号:US920827
申请日:1997-08-29
申请人: Tsuneya Ohno , Akio Matsuhisa , Hirotsugu Uehara , Soji Eda
发明人: Tsuneya Ohno , Akio Matsuhisa , Hirotsugu Uehara , Soji Eda
IPC分类号: C12N15/09 , C12N15/11 , C12Q1/68 , C12R1/01 , C12R1/19 , C12R1/22 , C12R1/385 , G01N33/53 , G01N33/566 , C07H21/04
CPC分类号: C12Q1/689 , C12Q2600/156
摘要: DNA probes for diagnosing infectious diseases involving Staphylococcus epidermidis and methods of using such probes are provided.
摘要翻译: 提供了用于诊断涉及表皮葡萄球菌感染性疾病的DNA探针和使用这种探针的方法。
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8.Probe for diagnosing Escherichia coli, Klebsiella pneumonieae or Enterobacter cloacae 失效
标题翻译: 探测用于诊断大肠杆菌,肺炎克雷伯杆菌或阴沟肠杆菌公开(公告)号:US5763188A
公开(公告)日:1998-06-09
申请号:US920812
申请日:1997-08-29
申请人: Tsuneya Ohno , Akio Matsuhisa , Hirotsugu Uehara , Soji Eda
发明人: Tsuneya Ohno , Akio Matsuhisa , Hirotsugu Uehara , Soji Eda
IPC分类号: C12N15/09 , C12N15/11 , C12Q1/68 , C12R1/01 , C12R1/19 , C12R1/22 , C12R1/385 , G01N33/53 , G01N33/566 , C07H21/04
CPC分类号: C12Q1/689 , C12Q2600/156
摘要: DNA probes for diagnosing infectious diseases involving Escherichia coli, Klebsielkli pneunmoniae or Enterobacter cloacae and methods of using such probes are provided.
摘要翻译: 提供了用于诊断涉及大肠杆菌,克雷伯氏菌或阴沟肠杆菌的感染性疾病的DNA探针以及使用这种探针的方法。
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