公开(公告)号：US20150071970A1

公开(公告)日：2015-03-12

申请号：US14444149

申请日：2014-07-28

Applicant: Hisamitsu Pharmaceutical Co., Inc.

Inventor： Seiji Tokumoto ,  Hirotoshi Adachi ,  Tetsuji Kuwahara

IPC: A61K39/39 ,  A61N1/32 ,  A61M37/00 ,  A61K39/145 ,  C12N7/00

CPC classification number: A61K39/39 ,  A61K9/0009 ,  A61K9/0014 ,  A61K9/0021 ,  A61K9/006 ,  A61K39/145 ,  A61K47/10 ,  A61K47/12 ,  A61K47/26 ,  A61K47/34 ,  A61K2039/53 ,  A61K2039/54 ,  A61K2039/541 ,  A61K2039/55511 ,  A61M37/0092 ,  A61N1/325 ,  A61N1/327 ,  C12N7/00 ,  C12N2760/16034 ,  Y02A50/401

Abstract: An adjuvant for transdermal or transmucosal administration which comprises at least one substance selected from an aliphatic alcohol, a free fatty acid and a fatty acid derivative but does not contain a substance represented by the following formula: wherein R3 and R4 may together form a cyclic ring, and R1 and R2 independently represent an alkyl side chain having 1 to 16 carbon atoms.

Abstract translation: 一种用于经皮或经粘膜给药的佐剂，其包含至少一种选自脂族醇，游离脂肪酸和脂肪酸衍生物的物质，但不含下式表示的物质：其中R3和R4可以一起形成环状 R 1和R 2独立地表示碳原子数1〜16的烷基侧链。