公开(公告)号：US20220117906A1

公开(公告)日：2022-04-21

申请号：US17431303

申请日：2020-01-23

Applicant: Hisamitsu Pharmaceutical Co., Inc.

Inventor： Ryo Tanaka ,  Kazuya Kominami ,  Naoyuki Uchida ,  Takito Shima

IPC: A61K9/70 ,  A61K47/32

Abstract: The problem addressed by the present invention is to provide a method for suppressing cold flow during packaging or application, regardless of the properties or concentration of a drug, in a patch containing a drug and an acrylic adhesive base in an adhesive layer. The present invention relates to a method for suppressing cold flow of a patch equipped with a support layer and an adhesive layer containing a drug and an acrylic adhesive base, wherein the method causes calcium silicate to be contained in the adhesive layer.

公开(公告)号：US12178922B2

公开(公告)日：2024-12-31

申请号：US17244552

申请日：2021-04-29

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Ryo Tanaka ,  Hideaki Ohashi ,  Naruhide Miyoshi ,  Takito Shima ,  Naoko Fujita ,  Yasunari Michinaka

IPC: A61K9/70 ,  A61K31/192 ,  A61K31/196 ,  A61K31/405 ,  A61K47/12 ,  A61K47/20 ,  A61K47/32

Abstract: The patch of the present invention comprises a backing layer and an adhesive layer laminated on the backing layer, wherein a water vapor transmission rate of the backing layer is 400 g/m2·24 hours or more, and the adhesive layer comprises a drug, dimethylsulfoxide and an adhesive. Such a patch does not fall off easily even after long wear.

公开(公告)号：US11020356B2

公开(公告)日：2021-06-01

申请号：US16474213

申请日：2017-12-26

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Ryo Tanaka ,  Hideaki Ohashi ,  Naruhide Miyoshi ,  Takito Shima ,  Naoko Fujita ,  Yasunari Michinaka

IPC: A61K9/70 ,  A61K31/192 ,  A61K31/196 ,  A61K31/405 ,  A61K47/12 ,  A61K47/20 ,  A61K47/32

Abstract: The patch of the present invention comprises a backing layer and an adhesive layer laminated on the backing layer, wherein a water vapor transmission rate of the backing layer is 400 g/m2·24 hours or more, and the adhesive layer comprises a drug, dimethylsulfoxide and an adhesive. Such a patch does not fall off easily even after long wear.