公开(公告)号：US07709248B2

公开(公告)日：2010-05-04

申请号：US10486022

申请日：2003-05-30

申请人： Hisayuki Yamatsu ,  Motohiro Furuki ,  Masanobu Yamamoto

发明人： Hisayuki Yamatsu ,  Motohiro Furuki ,  Masanobu Yamamoto

IPC分类号： G01N33/53 ,  C12Q1/00 ,  C12Q1/68

CPC分类号： G01N21/645 ,  G01N21/6428 ,  G01N33/54373 ,  G01N2021/6439 ,  G01N2021/6482

摘要： To provide a bioassay system or the like, which can solve the problem of allocating spaces above detecting sections and can also stabilize servo-controlled operation of a disk-shaped plate.Provided is a bioassay system (U) or the like, which is equipped with at least means for immobilizing a nucleotide chain, a peptide, a protein, a lipid, a low molecular-weight compound, a liposome or any other biological substance as a detection substance (D) in a detecting section (3), dropping a target-substance containing solution (S) onto the immobilized detection substance (D), and causing the detection substance (D) and the target substance (T) to interact with each other to prepare a reaction product (R); and means for condensing fluorescence (F), which has been emitted from the fluorescence-labeled substance (D) by irradiating excitation light (P) of a specific wavelength onto the reaction product (R), by a lens (5) arranged on a side of a back surface (102) of the reaction section (3) to determine an intensity of the fluorescence (F).

摘要翻译： 为了提供生物分析系统等，其可以解决在检测部分上方分配空间的问题，并且还可以稳定盘形板的伺服控制操作。 提供了一种生物测定系统（U）等，它们至少装备有用于将核苷酸链，肽，蛋白质，脂质，低分子量化合物，脂质体或任何其它生物物质固定的方法，作为 在检测部（3）中检测物质（D），将含有目标物质的溶液（S）滴加到固定化检测物质（D）上，使检测物质（D）和目标物质（T）与 彼此制备反应产物（R）; 以及通过用布置在反应产物（R）上的透镜（5）将特定波长的激发光（P）照射到反应产物（R）上而从荧光标记物质（D）发射的荧光（F）的装置 反应部分（3）的背表面（102）的侧面以确定荧光强度（F）。

公开(公告)号：US20050048595A1

公开(公告)日：2005-03-03

申请号：US10486022

申请日：2003-05-30

申请人： Hisayuki Yamatsu ,  Motohiro Furuki ,  Masanobu Yamamoto

发明人： Hisayuki Yamatsu ,  Motohiro Furuki ,  Masanobu Yamamoto

IPC分类号： C12M1/00 ,  C12M1/34 ,  G01N21/64 ,  G01N33/53 ,  G01N33/543 ,  G01N33/58 ,  G01N37/00 ,  C12Q1/34

CPC分类号： G01N21/645 ,  G01N21/6428 ,  G01N33/54373 ,  G01N2021/6439 ,  G01N2021/6482

摘要： To provide a bioassay system or the like, which can solve the problem of allocating spaces above detecting sections and can also stabilize servo-controlled operation of a disk-shaped plate. Provided is a bioassay system (U) or the like, which is equipped with at least means for immobilizing a nucleotide chain, a peptide, a protein, a lipid, a low molecular-weight compound, a liposome or any other biological substance as a detection substance (D) in a detecting section (3), dropping a target-substance containing solution (S) onto the immobilized detection substance (D), and causing the detection substance (D) and the target substance (T) to interact with each other to prepare a reaction product (R); and means for condensing fluorescence (F), which has been emitted from the fluorescence-labeled substance (D) by irradiating excitation light (P) of a specific wavelength onto the reaction product (R), by a lens (5) arranged on a side of a back surface (102) of the reaction section (3) to determine an intensity of the fluorescence (F).

摘要翻译： 为了提供生物分析系统等，其可以解决在检测部分上方分配空间的问题，并且还可以稳定盘形板的伺服控制操作。 提供了一种生物测定系统（U）等，它们至少装备有用于将核苷酸链，肽，蛋白质，脂质，低分子量化合物，脂质体或任何其它生物物质固定的方法，作为 在检测部（3）中检测物质（D），将含有目标物质的溶液（S）滴加到固定化检测物质（D）上，使检测物质（D）和目标物质（T）与 彼此制备反应产物（R）; 以及通过用布置在反应产物（R）上的透镜（5）将特定波长的激发光（P）照射到反应产物（R）上而从荧光标记物质（D）发射的荧光（F）的装置 反应部分（3）的背表面（102）的侧面以确定荧光强度（F）。

公开(公告)号：US20110008879A1

公开(公告)日：2011-01-13

申请号：US12888102

申请日：2010-09-22

申请人： Motohiro Furuki ,  Hisayuki Yamatsu

发明人： Motohiro Furuki ,  Hisayuki Yamatsu

IPC分类号： C12M1/34

CPC分类号： G01N33/54366

摘要： A bioassay substrate high in integration amount, free in grouping of substances, low in cost, and the like are provided. Specifically, a bioassay substrate includes detection surfaces S on which detection substances can be solidified, the detection surfaces S is provided on a surface of a disk form substrate capable of reading out record information optically, and the detection surfaces S is provided in groove structures (pits) provided in the surface of the substrate radially as viewed on the upper side at predetermined intervals. A bioassay system using the bioassay substrate and a readout system are also provided.

摘要翻译： 提供了一体化量高，物质分组自由，成本低的生物测定基板等。 具体地，生物测定基板包括检测物质可以固化的检测面S，检测面S设置在能够光学读出记录信息的盘状基板的表面上，检测面S设置在槽结构体 凹坑）以预定间隔从上侧观察放射状地设置在基板的表面中。 还提供了使用生物测定基板和读出系统的生物测定系统。

公开(公告)号：US6048669A

公开(公告)日：2000-04-11

申请号：US112946

申请日：1998-07-10

申请人： Hisayuki Yamatsu ,  Minoru Takeda ,  Motohiro Furuki

发明人： Hisayuki Yamatsu ,  Minoru Takeda ,  Motohiro Furuki

IPC分类号： G11B7/125 ,  G03F7/20 ,  G11B7/26 ,  H01L21/027

CPC分类号： G11B7/261 ,  Y10S430/146

摘要： In an exposure device 20 for an optical disc master disc, the power density of light beam which is converged until the diffraction limit level by using a light source laser 1 of far ultraviolet radiation and an objective lens 7 having a numerical aperture of 0.85 or more is set to 4.upsilon..times.10.sup.2 W/cm.sup.2 or more (.upsilon.)[cm/sec] represents a linear velocity of recording), and a photoresist 8 on the master disc 9 of the optical disc is subjected to light exposure and heat treatment at the same time.

摘要翻译： 在用于光盘母盘的曝光装置20中，通过使用远紫外线辐射的光源激光器1和数值孔径为0.85以上的物镜7会聚直到衍射极限水平的光束的功率密度 设定为4倍以上×102W / cm 2以上（以上）[cm / sec]表示记录的线速度），光盘的母盘9上的光致抗蚀剂8经受曝光和热处理 同时。

公开(公告)号：US08211380B2

公开(公告)日：2012-07-03

申请号：US12888102

申请日：2010-09-22

申请人： Motohiro Furuki ,  Hisayuki Yamatsu

发明人： Motohiro Furuki ,  Hisayuki Yamatsu

IPC分类号： G01N33/00

CPC分类号： G01N33/54366

摘要： A bioassay substrate high in integration amount, free in grouping of substances, low in cost, and the like are provided. Specifically, a bioassay substrate includes detection surfaces S on which detection substances can be solidified, the detection surfaces S is provided on a surface of a disk form substrate capable of reading out record information optically, and the detection surfaces S is provided in groove structures (pits) provided in the surface of the substrate radially as viewed on the upper side at predetermined intervals. A bioassay system using the bioassay substrate and a readout system are also provided.

摘要翻译： 提供了一体化量高，物质分组自由，成本低的生物测定基板等。 具体地，生物测定基板包括检测物质可以固化的检测面S，检测面S设置在能够光学读出记录信息的盘状基板的表面上，检测面S设置在槽结构体 凹坑）以预定间隔从上侧观察放射状地设置在基板的表面中。 还提供了使用生物测定基板和读出系统的生物测定系统。

公开(公告)号：US06214528B1

公开(公告)日：2001-04-10

申请号：US09161670

申请日：1998-09-29

申请人： Minoru Takeda ,  Hisayuki Yamatsu ,  Motohiro Furuki

发明人： Minoru Takeda ,  Hisayuki Yamatsu ,  Motohiro Furuki

IPC分类号： G03F720

CPC分类号： G11B7/261 ,  Y10S430/146

摘要： A photoresist is applied onto a substrate, the photoresist-coated substrate is exposed to a laser beam of 300 nm or less in wavelength to form a latent image indicative of an information signal, and the photoresist on the substrate is developed to form a pit/groove pattern indicating the information signal. The photoresist has a mean value of 0.1 or less between extinction coefficients before and after the exposure to the laser beam.

摘要翻译： 将光致抗蚀剂施加到基板上，将光致抗蚀剂涂覆的基板暴露于波长为300nm或更小的激光束，以形成指示信息信号的潜像，并且将基板上的光致抗蚀剂显影以形成凹坑/ 凹槽图案指示信息信号。 光致抗蚀剂在暴露于激光束之前和之后的消光系数之间的平均值为0.1或更小。

公开(公告)号：US20050014286A1

公开(公告)日：2005-01-20

申请号：US10477587

申请日：2003-03-14

申请人： Motohiro Furuki ,  Hisayuki Yamatsu

发明人： Motohiro Furuki ,  Hisayuki Yamatsu

IPC分类号： G01N33/543 ,  G01N33/566 ,  C12M1/34 ,  G01N33/558

CPC分类号： G01N33/54366

摘要： A bioassay substrate high in integration amount, free in grouping of substances, low in cost, and the like are provided. Specifically, a bioassay substrate includes detection surfaces S on which detection substances can be solidified, the detection surfaces S is provided on a surface of a disk form substrate capable of reading out record information optically, and the detection surfaces S is provided in groove structures (pits) provided in the surface of the substrate radially as viewed on the upper side at predetermined intervals. A bioassay system using the bioassay substrate and a readout system are also provided.

摘要翻译： 提供了一体化量高，物质分组自由，成本低的生物测定基板等。 具体地，生物测定基板包括检测物质可以固化的检测面S，检测面S设置在能够光学读出记录信息的盘状基板的表面上，检测面S设置在槽结构体 凹坑）以预定间隔从上侧观察放射状地设置在基板的表面中。 还提供了使用生物测定基板和读出系统的生物测定系统。

公开(公告)号：US08379503B2

公开(公告)日：2013-02-19

申请号：US13170270

申请日：2011-06-28

申请人： Hisayuki Yamatsu ,  Tetsuhiro Sakamoto

发明人： Hisayuki Yamatsu ,  Tetsuhiro Sakamoto

IPC分类号： G11B7/00

CPC分类号： G11B7/00455 ,  B82Y10/00 ,  G11B7/0908 ,  G11B7/0938 ,  G11B7/1275 ,  G11B2007/0013 ,  G11B2007/00457

摘要： An optical information recording reproduction apparatus includes: a first light beam source; a second light beam source emitting a beam with a wavelength shorter than that of the first light beam source; and an object lens condensing the beams from the first and second light beam sources to an optical information recording medium. When information is recorded in the optical information recording medium, a recording beam is emitted from the first light beam source and a beam used to generate a signal for controlling a position of the object lens is emitted from the second light beam source. When the information of the optical information recording medium is reproduced, a reproduction beam is emitted from the second light beam source.

摘要翻译： 一种光信息记录再现装置，包括：第一光束源; 发射波长短于第一光束源波长的光束的第二光束源; 以及将来自第一和第二光束源的光束聚光到光学信息记录介质的物镜。 当信息被记录在光学信息记录介质中时，从第一光束源发出记录光束，并且从第二光束源发射用于产生用于控制物镜的位置的信号的光束。 当再现光信息记录介质的信息时，从第二光束源发射再现光束。

公开(公告)号：US08223610B2

公开(公告)日：2012-07-17

申请号：US12595012

申请日：2009-02-05

申请人： Hisayuki Yamatsu ,  Kimihiro Saito ,  Seiji Kobayashi

发明人： Hisayuki Yamatsu ,  Kimihiro Saito ,  Seiji Kobayashi

IPC分类号： G11B7/0065

CPC分类号： G03H1/18 ,  G03H1/26 ,  G03H2001/184 ,  G11B7/00452 ,  G11B7/0065 ,  G11B7/00781 ,  G11B7/0938 ,  G11B7/1275 ,  G11B7/24038 ,  G11B7/24044 ,  G11B7/268

摘要： An initialization apparatus that has a simplified configuration and that forms an initial hologram in an information recording medium is provided. An initialization apparatus (10) rotates an optical disk (100) and emits blue light beams (Lb1) and (Lb2) to either side of the optical disk (100) while causing a red light beam (Lr1) to follow a track formed in a reference layer (102). Thus, the initialization apparatus (10) can perform an initialization process in which a linear initial hologram IH is formed in a recording layer (101) in a spiral pattern that corresponds to the track formed in a reference layer (102). Accordingly, the initialization apparatus (10) can form a planar initial hologram layer (YH) with significantly reduced optical energy or thermal energy emitted to the optical disk (100) at one time.

摘要翻译： 提供了具有简化配置并且在信息记录介质中形成初始全息图的初始化装置。 初始化装置（10）使光盘（100）旋转并将蓝色光束（Lb1）和（Lb2）发射到光盘（100）的任一侧，同时使红色光束（Lr1）跟随形成在 参考层（102）。 因此，初始化装置（10）可以执行初始化处理，其中线性初始全息图1H以对应于形成在参考层（102）中的轨道的螺旋图案形成在记录层（101）中。 因此，初始化装置（10）可以一次形成平面初始全息图层（YH），其具有显着降低的光能或发射到光盘（100）的热能。

公开(公告)号：US20100172228A1

公开(公告)日：2010-07-08

申请号：US12451855

申请日：2009-04-02

申请人： Kimihiro Saito ,  Hisayuki Yamatsu

发明人： Kimihiro Saito ,  Hisayuki Yamatsu

IPC分类号： G11B7/135 ,  G11B7/0037 ,  G11B7/00

CPC分类号： G11B7/00452 ,  G11B7/0065 ,  G11B7/0938 ,  G11B7/1275 ,  G11B7/1353 ,  G11B7/1374 ,  G11B7/1376 ,  G11B7/13922 ,  G11B7/13925 ,  G11B7/24044 ,  G11B7/2405 ,  G11B2007/0006 ,  G11B2007/0009

摘要： The present invention makes it possible to use an optical pickup in common with conventional optical disks. In a three-dimensional mark recording layer (111v) of a voluminal medium (100v), information is recorded by forming a three-dimensional record mark (RM) in the vicinity of the focus (Fb) of a blue light beam (Lb) according to the blue light beam (Lb) that is concentrated and has a light intensity equal to or larger than a predetermined intensity. The information is reproduced from the three-dimensional mark recording layer (111v) on the basis of a reproducing blue light beam (Lbr) deriving from irradiation of the blue light beam (Lb). A servo layer (114v) of the voluminal medium (100v) reflects at least part of the red light beam (Lr) which is irradiated in order to square the position of the blue light beam (Lb) in the three-dimensional mark recording layer (111v) with an arbitrary target mark position and whose wavelength is different from that of the blue light beam (Lb). The servo layer (114v) is separated by approximately 0.6 mm in the light-axis (Lx) direction of the red light beam (Lr) from the incident surface (100vA) to which the red light beam (Lr) is routed.

摘要翻译： 本发明使得可以使用与常规光盘相同的光学拾取器。 在体积介质（100v）的三维标记记录层（111v）中，通过在蓝色光束（Lb）的焦点（Fb）附近形成三维记录标记（RM）来记录信息， 根据浓缩的蓝色光束（Lb），具有等于或大于预定强度的光强度。 基于从蓝色光束（Lb）的照射导出的再现蓝色光束（Lbr），从三维标记记录层（111v）再现信息。 体积介质（100v）的伺服层（114v）反射被照射的红色光束（Lr）的至少一部分，以将三维标记记录层中的蓝色光束（Lb）的位置平方 （111v），其具有任意的目标标记位置，并且其波长与蓝色光束（Lb）的波长不同。 伺服层（114v）从与红色光束（Lr）相连的入射面（100vA）的红色光束（Lr）的光轴（Lx）方向分开约0.6mm。