公开(公告)号：USD828576S1

公开(公告)日：2018-09-11

申请号：US29594886

申请日：2017-02-23

Applicant: Hitachi High-Technologies Corporation

Designer： Hiroaki Nakagawa ,  Kengo Muramatsu

公开(公告)号：USD827151S1

公开(公告)日：2018-08-28

申请号：US29594889

申请日：2017-02-23

Applicant: Hitachi High-Technologies Corporation

Designer： Hiroaki Nakagawa ,  Kengo Muramatsu

公开(公告)号：USD827150S1

公开(公告)日：2018-08-28

申请号：US29594888

申请日：2017-02-23

Applicant: Hitachi High-Technologies Corporation

Designer： Hiroaki Nakagawa ,  Kengo Muramatsu

公开(公告)号：US09862921B2

公开(公告)日：2018-01-09

申请号：US14896123

申请日：2014-06-17

Applicant: Hitachi High-Technologies Corporation

Inventor： Naoko Senda ,  Yoko Inoue ,  Hiroaki Nakagawa ,  Akihiro Shimase ,  Ryota Nakajima ,  Kazumichi Imai ,  Shizu Takeda

IPC: C12M1/34 ,  C12M1/36 ,  G01N33/68 ,  G01N33/50

CPC classification number: C12M41/46 ,  C12M41/48 ,  G01N33/5005 ,  G01N33/6806 ,  G01N33/6812

Abstract: There is provided a method for noninvasively evaluating the cell state (proliferation, multi-layering, and differentiation) of a cell sheet as a mimic tissue at the time of culturing the cell sheet. The method is characterized in that an analysis of an amino acid is conducted with the use of the culture supernatant of a cell sheet to monitor a change in the concentration of any amino acid selected from a group of 5-species of amino acids (Ile, Val, Ser, Leu, and Ala), thereby making a determination.