公开(公告)号：US12122791B2

公开(公告)日：2024-10-22

申请号：US17842612

申请日：2022-06-16

Applicant: Hoffmann-La Roche Inc.

Inventor： Jean-Michel Adam ,  Serena Maria Fantasia ,  Daniel Vincent Fishlock ,  Fabienne Hoffmann-Emery ,  Gerard Moine ,  Christophe Pfleger ,  Christian Moessner

IPC: C07D519/00 ,  B01J23/44 ,  B01J23/755

CPC classification number: C07D519/00 ,  B01J23/44 ,  B01J23/755

Abstract: The present invention relates to a process for the preparation of 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one derivatives useful as pharmaceutically active compounds.

公开(公告)号：US20200216472A1

公开(公告)日：2020-07-09

申请号：US16824212

申请日：2020-03-19

Applicant: Hoffmann-La Roche Inc.

Inventor： Jean-Michel Adam ,  Serena Maria Fantasia ,  Daniel Vincent Fishlock ,  Fabienne Hoffmann-Emery ,  Gerard Moine ,  Christophe Pfleger ,  Christian Moessner

IPC: C07D519/00 ,  B01J23/44 ,  B01J23/755

Abstract: The present invention relates to a process for the preparation of 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one derivatives useful as pharmaceutically active compounds.

公开(公告)号：US20220324881A1

公开(公告)日：2022-10-13

申请号：US17842612

申请日：2022-06-16

Applicant: Hoffmann-La Roche Inc.

Inventor： Jean-Michel Adam ,  Serena Maria Fantasia ,  Daniel Vincent Fishlock ,  Fabienne Hoffmann-Emery ,  Gerard Moine ,  Christophe Pfeger ,  Christian Moessner

IPC: C07D519/00 ,  B01J23/44 ,  B01J23/755

Abstract: The present invention relates to a process for the preparation of 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one derivatives useful as pharmaceutically active compounds.