专利检索 ap:("Hoffmann-La Roche Inc.") AND inv:"Christian Moessner" 第 1 页

1.

发明授权
Process for the preparation of 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8- dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one derivatives 有权

公开(公告)号：US12122791B2

公开(公告)日：2024-10-22

申请号：US17842612

申请日：2022-06-16

申请人： Hoffmann-La Roche Inc.

发明人： Jean-Michel Adam , Serena Maria Fantasia , Daniel Vincent Fishlock , Fabienne Hoffmann-Emery , Gerard Moine , Christophe Pfleger , Christian Moessner

IPC分类号： C07D519/00 , B01J23/44 , B01J23/755

CPC分类号： C07D519/00 , B01J23/44 , B01J23/755

摘要： The present invention relates to a process for the preparation of 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one derivatives useful as pharmaceutically active compounds.

2.

发明公开
SYNTHESIS OF [1,2,3]TRIAZOLO[4,5-D]PYRIMIDINES 审中-公开

公开(公告)号：US20240287084A1

公开(公告)日：2024-08-29

申请号：US18644781

申请日：2024-04-24

申请人： Hoffmann-La Roche Inc.

发明人： Jean-Michel Adam , Uwe Grether , Christian Moessner , Paolo Tosatti

IPC分类号： C07D487/04

CPC分类号： C07D487/04

摘要： The present invention relates to a process for the preparation of [1,2,3]triazolo[4,5-d]pyrimidine derivatives useful as pharmaceutically active compounds, in particular 1-[5-tert-butyl-3-[(1-methyltetrazol-5-yl)methyl]triazolo[4,5-d]pyrimidin-7-yl]pyrrolidin-3-ol.

3.

发明申请
PROCESS FOR THE PREPARATION OF 7-(4,7-DIAZASPIRO[2.5]OCTAN-7-YL)-2-(2,8-DIMETHYLIMIDAZO[1,2-B]PYRIDAZIN-6-YL)PYRIDO[1,2-A]PYRIMIDIN-4-ONE DERIVATIVES 审中-公开

公开(公告)号：US20200216472A1

公开(公告)日：2020-07-09

申请号：US16824212

申请日：2020-03-19

申请人： Hoffmann-La Roche Inc.

发明人： Jean-Michel Adam , Serena Maria Fantasia , Daniel Vincent Fishlock , Fabienne Hoffmann-Emery , Gerard Moine , Christophe Pfleger , Christian Moessner

IPC分类号： C07D519/00 , B01J23/44 , B01J23/755

摘要： The present invention relates to a process for the preparation of 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one derivatives useful as pharmaceutically active compounds.

4.

发明申请
PROCESS FOR THE PREPARATION OF 7-(4,7-DIAZASPIRO[2.5]OCTAN-7-YL)-2-(2,8-DIMETHYLIMIDAZO[1,2-B]PYRIDAZIN-6-YL)PYRIDO[1,2-A]PYRIMIDIN-4-ONE DERIVATIVES 有权

公开(公告)号：US20220324881A1

公开(公告)日：2022-10-13

申请号：US17842612

申请日：2022-06-16

申请人： Hoffmann-La Roche Inc.

发明人： Jean-Michel Adam , Serena Maria Fantasia , Daniel Vincent Fishlock , Fabienne Hoffmann-Emery , Gerard Moine , Christophe Pfeger , Christian Moessner

IPC分类号： C07D519/00 , B01J23/44 , B01J23/755

摘要： The present invention relates to a process for the preparation of 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one derivatives useful as pharmaceutically active compounds.