公开(公告)号：US4240964A

公开(公告)日：1980-12-23

申请号：US64906

申请日：1979-08-08

申请人： Horst Koenig ,  Albrecht Franke ,  Fritz-Frieder Frickel ,  Wolfgang Steglich ,  Norbert Engel

发明人： Horst Koenig ,  Albrecht Franke ,  Fritz-Frieder Frickel ,  Wolfgang Steglich ,  Norbert Engel

IPC分类号： C07D207/32 ,  C07D207/333 ,  C07D207/44

CPC分类号： C07D207/333 ,  Y02P20/55

摘要： 2-(o-Hydroxyphenyl)-pyrrole and a process for its preparation, wherein o-benzyloxybenzoic acid allylamide is reacted with phosgene in an inert solvent, the resulting imide-chloride is cyclized in the presence of a strong sterically hindered base and the benzyl protective group is then removed by hydrogenolysis.2-(o-Hydroxyphenyl)-pyrrole is a valuable intermediate for the synthesis of drugs. In particular, alkylamino-hydroxypropyl ethers thereof can, because of their .beta.-sympatholytic actions, be used for the treatment of coronary cardiac diseases, cardiac arrhythmias and hypertonia.

摘要翻译： 2-（邻羟基苯基） - 吡咯及其制备方法，其中将邻 - 苄氧基苯甲酸烯丙基酰胺与光气在惰性溶剂中反应，得到的酰亚胺氯化物在强空间位阻碱存在下环化， 然后通过氢解除去保护基团。 2-（邻羟基苯基） - 吡咯是合成药物的有价值的中间体。 特别地，其烷基氨基 - 羟丙基醚可以由于其β-溶栓作用而用于治疗冠心病，心律失常和高渗。

公开(公告)号：USRE41162E1

公开(公告)日：2010-03-02

申请号：US10909249

申请日：2004-07-30

申请人： Norbert Engel ,  Eunan Muldoon ,  Ralph Wadlinger ,  Reginald L. Allen ,  Patrick W. McFarland ,  Guatam Patwari ,  John H. Pokropinski ,  Gail E. Tate ,  Ronnie E. Dean

发明人： Norbert Engel ,  Eunan Muldoon ,  Ralph Wadlinger ,  Reginald L. Allen ,  Patrick W. McFarland ,  Guatam Patwari ,  John H. Pokropinski ,  Gail E. Tate ,  Ronnie E. Dean

IPC分类号： G06F9/44

CPC分类号： G06F8/656

摘要： Platform and/or application software on all online, machine/servers in a cluster is updated without manually taking each machine/server offline. Initially, platform and/or application software for updating is stored in respective directories in an APPLY phase. Next, the new platform and/or application software is activated with or without a trial/test phase in an ACTIVATE phase. Where the new platform and/or application software is activated with a trial/test phase, a ROLLBACK phase is either automatically or manually invoked by the application in the event of a failure of the new software for backing out the new platform and/or application software and reactivating the previous platform and/or application software. An OFFICLAL phase then transitions the new platform and/or application software to the official state followed by a REACTIVATE phase for reactivating the backup copy of the previous/old platform and/or application software after the new software has been made official.

摘要翻译： 更新群集中所有联机，机器/服务器上的平台和/或应用程序软件，而无需手动将每个计算机/服务器脱机。 最初，用于更新的平台和/或应用软件存储在APPLY阶段的相应目录中。 接下来，新的平台和/或应用程序软件在ACTIVATE阶段启动或不启用试用/测试阶段。 在新的平台和/或应用软件通过试用/测试阶段激活的情况下，如果新软件出现故障而退出新平台和/或应用程序，应用程序会自动或手动调用ROLLBACK阶段 软件并重新激活以前的平台和/或应用软件。 OFFICLAL阶段随后将新的平台和/或应用软件转换到官方状态，随后是REACTIVATE阶段，以在新软件被正式授权之后重新激活之前/旧平台和/或应用软件的备份副本。

公开(公告)号：US06681389B1

公开(公告)日：2004-01-20

申请号：US09514109

申请日：2000-02-28

申请人： Norbert Engel ,  Eunan Muldoon ,  Ralph Wadlinger

发明人： Norbert Engel ,  Eunan Muldoon ,  Ralph Wadlinger

IPC分类号： G06F944

CPC分类号： G06F8/656

摘要： Platform and/or application software on all online, machine/servers in a cluster is updated without manually taking each machine/server offline. Initially, platform and/or application software for updating is stored in respective directories in an APPLY phase. Next, the new platform and/or application software is activated with or without a trial/test phase in an ACTIVATE phase. Where the new platform and/or application software is activated with a trial/test phase, a ROLLBACK phase is either automatically or manually invoked by the application in the event of a failure of the new software for backing out the new platform and/or application software and reactivating the previous platform and/or application software. An OFFICLAL phase then transitions the new platform and/or application software to the official state followed by a REACTIVATE phase for reactivating the backup copy of the previous/old platform and/or application software after the new software has been made official.

摘要翻译： 更新群集中所有联机，机器/服务器上的平台和/或应用程序软件，而无需手动将每个计算机/服务器脱机。 最初，用于更新的平台和/或应用软件存储在APPLY阶段的相应目录中。 接下来，新的平台和/或应用程序软件在ACTIVATE阶段启动或不启用试用/测试阶段。 在新的平台和/或应用软件通过试用/测试阶段激活的情况下，如果新软件出现故障而退出新平台和/或应用程序，应用程序会自动或手动调用ROLLBACK阶段 软件并重新激活以前的平台和/或应用软件。 OFFICLAL阶段随后将新的平台和/或应用软件转换到官方状态，随后是REACTIVATE阶段，以在新软件被正式授权之后重新激活之前/旧平台和/或应用软件的备份副本。