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1.3-(2-Acylamino-1-Hydroxyethyl)-Morpholine Derivatives and Their Use as Bace Inhibitors 有权
标题翻译: 3-(2-酰氨基-1-羟乙基) - 吗啉衍生物及其作为抑制剂的用途公开(公告)号:US20070225267A1
公开(公告)日:2007-09-27
申请号:US11574989
申请日:2005-09-20
申请人: Howard Broughton , Robert Dally , Timothy Durham , Maria Rosario Gonzalez-Garcia , Lilly Sa , Patric Hahn , Kenneth Henry , Todd Kohn , James McCarthy , Timothy Shepherd , Jon Erickson , Ana Bueno Melendo
发明人: Howard Broughton , Robert Dally , Timothy Durham , Maria Rosario Gonzalez-Garcia , Lilly Sa , Patric Hahn , Kenneth Henry , Todd Kohn , James McCarthy , Timothy Shepherd , Jon Erickson , Ana Bueno Melendo
IPC分类号: A61K31/5375 , A61K31/5377 , C07C217/48 , C07C271/20 , C07D265/30 , C07D265/32 , C07D413/12 , C07F7/18
CPC分类号: C07C271/20 , C07C233/36 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2603/74 , C07D265/30 , C07D265/32 , C07D413/12 , C07F7/1804
摘要: The present invention provides BACE inhibitors of Formula (I); methods for their use and preparation, and intermediates useful for their preparation.
摘要翻译: 本发明提供式(I)的BACE抑制剂; 使用和制备方法,以及可用于制备的中间体。