Bioadhesive progressive hydration tablets
    1.
    发明申请
    Bioadhesive progressive hydration tablets 失效
    生物粘附进行性水合片

    公开(公告)号:US20070031491A1

    公开(公告)日:2007-02-08

    申请号:US11431611

    申请日:2006-05-11

    IPC分类号: A61K9/22

    摘要: A bioadhesive controlled, extended release progressive hydration composition wherein the active ingredient may be protected from water or the surrounding environment, thereby protecting it from metabolism or from other degradation caused by moisture, enzymes, or pH effects, and making it bioavailable only at a controlled rate. The active ingredient may be protected from moisture during the manufacturing process, as necessary or desired, and more importantly may be protected from moisture and the immediate septic environment until well after the patient has applied the composition, and then only at a slow and controlled rate. It is by this process of progressive hydration that the active ingredient remains protected for many hours after administration. It is also by the process of progressive hydration that controlled and sustained release is achieved because only that part of the active ingredient that is the hydrated (aqueous) fraction of the composition is available for absorption (bioavailable).

    摘要翻译: 生物粘附控制的延长释放的进行性水合组合物,其中活性成分可以被保护免受水或周围环境的影响,从而保护其免受代谢或由水分,酶或pH影响引起的其它降解,并且仅在受控的 率。 活性成分可根据需要或需要在制造过程中得到保护,并且更重要的是可以保护免受潮湿和直接的败血症环境,直到患者施用组合物,然后仅以缓慢和受控的速率 。 正是通过这种进行性水合过程,活性成分在给药后保持多个小时。 还通过进行水合的过程,控制和持续释放是实现的,因为只有作为组合物的水合(水)部分的活性成分的那部分可用于吸收(生物可利用的)。

    Expandable stand-alone shelving assembly

    公开(公告)号:US11930922B1

    公开(公告)日:2024-03-19

    申请号:US18504691

    申请日:2023-11-08

    申请人: Howard Levine

    发明人: Howard Levine

    摘要: An expandable stand-alone shelving assembly includes a post assembly and an expandable shelf. The post assembly includes an elongated post and a sleeve coupled to the elongated post. The expandable shelf includes an aperture, a first half, a second half, and an internal mechanism. The aperture accepts the sleeve of the post assembly. The first half of the expandable shelf includes a surface, a top end, and a bottom end. The second half of the expandable shelf includes an angled portion extending downwards from a surface of the second half. The internal mechanism includes a reinforcement bar connecting the top end and the bottom end of the first half, and a stop. The second half is slidably received within the first half. The stop of the internal mechanism engages with the angled portion of the second half to prevent the second half and first half from sliding apart.