公开(公告)号：US20150266210A1

公开(公告)日：2015-09-24

申请号：US14221995

申请日：2014-03-21

申请人： Howmedica Osteonics Corp.

发明人： Lin Song ,  Daniel E. Lawrynowicz ,  Kim-phuong Nguyen Le ,  Kevor Shane Tenhuisen

IPC分类号： B29B13/08 ,  A61L27/16 ,  B29B13/04 ,  B29B15/00 ,  B29B11/14 ,  B29B13/02

CPC分类号： B29B13/08 ,  A61L27/16 ,  B29B11/14 ,  B29B13/02 ,  B29B13/04 ,  B29B15/00 ,  B29C35/08 ,  B29C43/003 ,  B29C43/10 ,  B29C71/04 ,  B29C2035/0844 ,  B29C2035/085 ,  B29C2035/0877 ,  B29C2071/022 ,  B29K2023/0683 ,  B29K2105/253

摘要： A method for making an ultra-high weight polyethylene (UHMWPE) medical implant starts with obtaining a preform consolidated from UHMWPE resin. Thereafter the preform is hot isostaticly pressed at a temperature between 150° C. and 190° C. at a pressure up to 30,000 psi. After the hot isostatic pressing the preform is sequentially irradiated in a solid state at a total radiation dose of 2 to 10 MRad. The irradiated UHMWPE preform is then heated to a temperature of about 110° C. to about 190° C. for between 2 to 10 hours. The irradiated and heated preform is then cooled after each irradiation and heating to at or below 50° C., and thereafter a medical implant is formed from the preform. Alternately, the process can be performed on the medical implant itself.

摘要翻译： 用于制造超高分子量聚乙烯（UHMWPE）医用植入物的方法首先获得由UHMWPE树脂固结的预制件。 此后，在高达30,000psi的压力下，将预制件在150℃至190℃之间的温度下进行热等静压。 在热等静压之后，以2〜10Mrad的总辐射剂量，以固态依次照射预成型体。 然后将照射的UHMWPE预制件加热至约110℃至约190℃的温度2至10小时。 然后将辐射和加热的预制件在每次照射之后冷却并加热到等于或低于50℃，然后从预成型件形成医用植入物。 或者，该过程可以在医疗植入物本身上进行。