Methods for assessing the results of disc-based bioassays with standard computer optical drives
    1.
    发明授权
    Methods for assessing the results of disc-based bioassays with standard computer optical drives 有权
    用标准计算机光驱评估光盘生物测定结果的方法

    公开(公告)号:US08194514B2

    公开(公告)日:2012-06-05

    申请号:US12920100

    申请日:2009-03-02

    IPC分类号: G11B7/00

    摘要: Methods and systems are described for assessing the results of a bioassay between probe biomolecules and target biomolecules using conventional optical disk drive. particular methods involve: bonding the probe biomolecules to a polycarbonate (PC) surface of an optical disk having digital data comprising error-detection redundancies recorded thereon: introducing the target biomolecules to the PC surface of the optical disk in a vicinity of the bonded probe biomolecules; processing the bioassay to alter a manner in which a read light from the optical disk interacts optically with the optical disk in a vicinity of positive bioassay results where the target biomolecules have bonded to the probe biomolecules; reading the digital data from the optical disk using the optical drive and using the error-redundancies to detect errors in the digital data read by the optical drive; mapping the detected errors to corresponding locations on the optical disk; and determining that positive bioassay results have occurred at the locations of the detected errors.

    摘要翻译: 描述了用于评估使用常规光盘驱动器的探针生物分子和靶生物分子之间的生物测定结果的方法和系统。 特定的方法包括:将探针生物分子结合到具有数字数据的光盘的聚碳酸酯(PC)表面,该数字数据包括记录在其上的误差检测冗余:将目标生物分子引入键合探针生物分子附近的光盘的PC表面 ; 处理生物测定以改变来自光盘的读取光在光生物测定结果附近与光盘相互作用的方式,其中靶生物分子结合到探针生物分子; 使用光驱从光盘读取数字数据,并使用错误冗余来检测由光驱读取的数字数据中的错误; 将检测到的错误映射到光盘上的相应位置; 并确定在检测到的错误的位置处发生了积极的生物测定结果。

    METHODS FOR ASSESSING THE RESULTS OF DISC-BASED BIOASSAYS WITH STANDARD COMPUTER OPTICAL DRIVES
    2.
    发明申请
    METHODS FOR ASSESSING THE RESULTS OF DISC-BASED BIOASSAYS WITH STANDARD COMPUTER OPTICAL DRIVES 有权
    用标准计算机光学驱动器评估基于光盘的生物多样性结果的方法

    公开(公告)号:US20110103212A1

    公开(公告)日:2011-05-05

    申请号:US12920100

    申请日:2009-03-02

    IPC分类号: G11B7/00 H03M13/09

    摘要: Methods and systems are described for assessing the results of a bioassay between probe biomolecules and target biomolecules using a conventional optical disc drive. Particular methods involve: bonding the probe biomolecules to a polycarbonate (PC) surface of an optical disc having digital data comprising error-detection redundancies recorded thereon; introducing the target biomolecules to the PC surface of the optical disc in a vicinity of the bonded probe biomolecules; processing the bioassay to alter a manner in which a read light from the optical disc drive interacts optically with the optical disc in a vicinity of positive bioassay results where the target biomolecules have bonded to the probe biomolecules; reading the digital data from the optical disc using the optical drive and using the error-detection redundancies to detect errors in the digital data read by the optical drive; mapping the detected errors to corresponding locations on the optical disc; and determining that positive bioassay results have occurred at the locations of the detected errors.

    摘要翻译: 描述了用于评估使用常规光盘驱动器的探针生物分子和靶生物分子之间的生物测定结果的方法和系统。 具体方法包括:将探针生物分子结合到具有数字数据的光盘的聚碳酸酯(PC)表面,该数字数据包括记录在其上的误差检测冗余; 将靶标生物分子引入到键合探针生物分子附近的光盘的PC表面上; 处理生物测定以改变其中来自光盘驱动器的读取光与光盘相互作用的方式,其中靶生物分子结合到探针生物分子的阳性生物测定结果附近; 使用光驱读取来自光盘的数字数据,并使用错误检测冗余来检测由光驱读出的数字数据中的错误; 将检测到的错误映射到光盘上的相应位置; 并确定在检测到的错误的位置处发生了积极的生物测定结果。