Vial connector assembly for a medicament container
    1.
    发明授权
    Vial connector assembly for a medicament container 失效
    用于药物容器的小瓶连接器组件

    公开(公告)号:US5890610A

    公开(公告)日:1999-04-06

    申请号:US962897

    申请日:1997-11-03

    摘要: A connector assembly provided for efficient flow of liquid into and/or out of a vial, such as a vial containing a lyophilized drug. The connector assembly features a collar mountable to the rim of the vial in a locked position and thereafter removable by an end-user when disposal of the device is desired. A protective cap mountable over the collar includes an annulus-type ring at its proximal end which mounts over locking structure associated with the collar. The ring is secured to the protective cap via one or more user-severable connections. As the cap is urged proximally, the ring places the collar in the locked position with the vial rim, exerting an inwardly-directed force onto the locking structure to secure the collar to the vial rim. The cap can be separated from the ring at its user-severable connections, and the device used in its ordinary matter. When disposal is desired, the ring may be urged proximally out of engagement with the locking structure of the collar. The collar may thereafter be removed from the vial to facilitate separate disposal of those components.

    摘要翻译: 提供用于有效地将液体流入和/或流出小瓶(例如含有冻干药物的小瓶)的连接器组件。 连接器组件具有可在锁定位置安装到小瓶的边缘的轴环,并且此后可以在期望处理装置时由最终用户拆卸。 安装在套环上的保护盖包括在其近端处的环形环,其安装在与套环相关联的锁定结构上。 环通过一个或多个用户可分割的连接固定到保护盖上。 当帽被向近侧推动时,环将套环放置在具有小瓶边缘的锁定位置,对锁定结构施加向内的力,以将套环固定到小瓶边缘。 盖子可以在用户可分离的连接处与环分离,并且在其普通事物中使用该设备。 当需要处置时,可以将环向近侧推动脱离与套环的锁定结构的接合。 此后可以将颈环从小瓶中取出以便于这些部件的单独处置。

    Sterile vial connector assembly for efficient transfer of liquid
    2.
    发明授权
    Sterile vial connector assembly for efficient transfer of liquid 失效
    无菌小瓶连接器组件,用于有效转移液体

    公开(公告)号:US5785701A

    公开(公告)日:1998-07-28

    申请号:US714873

    申请日:1996-09-17

    摘要: A connector assembly is provided for efficient flow of liquid into and/or out of a vial, such as a vial containing a lyophilized drug. The connector assembly includes a spike and a stopper sleeve, both slidably mounted in the open top of the vial. The connector assembly includes a stopper affixed to the stopper sleeve and sealingly engaged in the open top of the vial. The stopper is slidably moveable in response to axial movement of the stopper sleeve. Movement of the stopper sleeve relative to the vial will move the stopper into or out of sealing engagement with the vial. The connector assembly further includes a spring for generating a small amount of axial movement of the spike, stopper sleeve and stopper after the stopper has been moved into the opened position in the vial. Movement of the spike, stopper sleeve and stopper generated by the spring will cause a sufficient change in pressure to overcome surface tension and initiate an efficient flow of fluid into or out of the vial.

    摘要翻译: 提供连接器组件用于有效地将液体流入和/或从小瓶中,例如含有冻干药物的小瓶中。 连接器组件包括尖头和塞子套筒,两者均可滑动地安装在小瓶的开口顶部。 连接器组件包括固定到止动套筒上并密封地接合在小瓶的开口顶部的止动件。 止动器响应于止动套筒的轴向运动而可滑动地移动。 止动器套筒相对于小瓶的移动将使止动器移动到与小瓶密封接合中。 连接器组件还包括弹簧,用于在塞子已经移动到小瓶中的打开位置之后产生尖钉,止动套筒和塞子的少量轴向运动。 由弹簧产生的尖钉,止动套筒和止动器的移动将导致压力的充分变化以克服表面张力并引发流体有效地流入或流出小瓶。

    Method and apparatus for fixing a connector assembly onto a vial with a
crimp cap
    4.
    发明授权
    Method and apparatus for fixing a connector assembly onto a vial with a crimp cap 失效
    用于将连接器组件固定到具有卷边帽的小瓶上的方法和装置

    公开(公告)号:US5925029A

    公开(公告)日:1999-07-20

    申请号:US937638

    申请日:1997-09-25

    IPC分类号: A61J1/00 A61J1/20 A61B19/00

    CPC分类号: A61J1/2096 A61J1/201

    摘要: A method and apparatus for attaching a connector assembly onto a vial is disclosed. The connector assembly features a protective cap, a collar attachable to the rim of the vial, and a crimp cap for securing the collar to the rim. A vial access device is contained within the collar. One or more ribs are provided adjacent a distal portion of the collar to seal against the stopper obturating the vial. The collar is provided with one or more slits which render the collar flexible in directions radial and axial to the central axis of the vial to compensate for variations in tolerances or dimensions present in the various components. The crimp cap can be supplied preattached to the collar in an uncrimped condition.

    摘要翻译: 公开了一种用于将连接器组件附接到小瓶上的方法和装置。 连接器组件具有保护帽,可附接到小瓶的边缘的套环以及用于将套环固定到边缘的压接帽。 套管内装有小瓶检修装置。 一个或多个肋设置在颈圈的远端部分附近,以密封堵塞小瓶的塞子。 套环设置有一个或多个狭缝,其使得套环沿着与小瓶的中心轴线径向和轴向的方向柔性,以补偿存在于各种部件中的公差或尺寸的变化。 卷边帽可以在未卷曲的状态下预先附着在衣领上。

    Method and apparatus for fixing a connector assembly onto a vial
    5.
    发明授权
    Method and apparatus for fixing a connector assembly onto a vial 失效
    将连接器组件固定到小瓶上的方法和装置

    公开(公告)号:US06213994B1

    公开(公告)日:2001-04-10

    申请号:US08938186

    申请日:1997-09-25

    IPC分类号: A61B1900

    摘要: A method and apparatus for attaching a connector assembly onto a vial is disclosed. The connector assembly features a protective cap, a collar attachable to the rim of the vial, and a locking ring disposed about the collar. A vial access device is contained within the collar. One or more ribs are provided adjacent a distal portion of the collar to seal against the stopper obturating the vial. The collar is provided with one or more slits which render the collar flexible in directions radial and axial to the central axis of the vial to compensate for variations in tolerances or dimensions present in the various components. Locking structure between the locking ring and the collar assures that the collar remains fixed to the vial.

    摘要翻译: 公开了一种用于将连接器组件附接到小瓶上的方法和装置。 连接器组件具有保护盖,可附接到小瓶的边缘的套环和围绕套环设置的锁定环。 套管内装有小瓶检修装置。 一个或多个肋设置在颈圈的远端部分附近,以密封堵塞小瓶的塞子。 套环设置有一个或多个狭缝,其使得套环沿着与小瓶的中心轴线径向和轴向的方向柔性,以补偿存在于各种部件中的公差或尺寸的变化。 锁定环和套环之间的锁定结构确保了套环保持固定在小瓶上。

    Vial transferset and method
    6.
    发明授权
    Vial transferset and method 失效
    样品瓶转移和方法

    公开(公告)号:US6003566A

    公开(公告)日:1999-12-21

    申请号:US31302

    申请日:1998-02-26

    摘要: The improved vial transfer assembly or vial transferset may be attached to a vial under sterile conditions and used to transfer fluid to or from a conventional vial. The transferset includes a tubular transfer member which is sealingly supported on the rim portion of a vial stopper, a piercing member having a piercing end reciprocally supported by an internal surface of the transfer member, a cap enclosing the tubular transfer member and a collar preferably formed of a malleable material which secures the assembly on the stopper, which is crimped beneath the vial rim. The piercing member has a generally longitudinal external channel which, upon piercing the planar portion of the stopper, establishes fluid communication with the vial through the tubular transfer member. The distal end of the tubular transfer member includes a Luer lock for establishing fluid communication to a syringe, IV set or the like. An annular lip on the proximate end of the tubular transfer member stretches and prestresses the central portion of the planar stopper rim and the piercing member is supported in the transferset such that the piercing end deforms the prestressed stopper rim portion.

    摘要翻译: 改进的小瓶传送组件或小瓶传输组可以在无菌条件下连接到小瓶,并用于将流体传送到常规小瓶或从常规小瓶传送流体。 传输组件包括密封地支撑在小瓶塞的边缘部分上的管状传送构件,具有由传送构件的内表面往复地支承的穿刺端的穿孔构件,封闭管状传送构件的盖子和优选地形成 一种可延展的材料,其将组件固定在塞子上,该塞子被压接在小瓶边缘下方。 刺穿构件具有大致纵向的外部通道,其在穿过止动件的平面部分时通过管状转移构件建立与小瓶的流体连通。 管状转移构件的远端包括用于建立与注射器,IV套等的流体连通的Luer锁。 管状转移构件的近端上的环形唇缘延伸并预应力于平面止动件边缘的中心部分,并且刺穿构件支撑在转移组件​​中,使得穿孔端使预应力止动件边缘部分变形。

    Multipositional resealable vial connector assembly for efficient
transfer of liquid
    7.
    发明授权
    Multipositional resealable vial connector assembly for efficient transfer of liquid 失效
    多位置可重复密封的小瓶连接器组件,用于有效转移液体

    公开(公告)号:US5873872A

    公开(公告)日:1999-02-23

    申请号:US714874

    申请日:1996-09-17

    摘要: A connector assembly is provided for efficient flow of liquid into and/or out of a vial, such as a vial containing a lyophilized drug. The connector assembly includes a spike slidably mounted in the open top of the vial. The connector assembly further includes a stopper sealingly engaged in the open top of the vial and slidably moveable in response to the axially movement of the spike. Thus, movement of the spike relative to the vial will move the stopper into or out of sealing engagement with the vial. The connector assembly further includes a spring for generating a small amount of axial movement of the spike after the stopper has been moved into the opened position in the vial. Movement of the spike generated by the spring will cause a sufficient change in pressure to overcome surface tension and initiate an efficient flow of fluid into or out of the vial.

    摘要翻译: 提供连接器组件用于有效地将液体流入和/或从小瓶中,例如含有冻干药物的小瓶中。 连接器组件包括可滑动地安装在小瓶的开口顶部的钉。 连接器组件还包括塞子,其密封地接合在小瓶的开口顶部并且响应于尖峰的轴向移动而可滑动地移动。 因此,尖峰相对于小瓶的运动将使塞子移动到与小瓶密封接合或脱离密封接合。 连接器组件还包括弹簧,用于在塞子已经移动到小瓶中的打开位置之后产生尖峰的少量的轴向移动。 由弹簧产生的尖峰的运动将导致压力的充分变化以克服表面张力并引发流体有效地流入或流出小瓶。

    Vial transferset and method
    8.
    发明授权
    Vial transferset and method 有权
    样品瓶转移和方法

    公开(公告)号:US06378576B2

    公开(公告)日:2002-04-30

    申请号:US09876543

    申请日:2001-06-07

    IPC分类号: B65B104

    摘要: This invention relates to an improved vial transfer assembly or vial transferset which may be attached to a vial under sterile conditions and used to transfer fluid to or from a conventional vial. The transferset includes a tubular transfer member which is sealingly supported on the rim portion of a vial stopper, a piercing member having a piercing end reciprocally supported by an internal surface of the transfer member, a cap enclosing the tubular transfer member and a collar preferably formed of a malleable material which secures the assembly on the stopper, which is crimped beneath the vial rim. The piercing member has a generally longitudinal external channel which, upon piercing the planar portion of the stopper, establishes fluid communication with the vial through the tubular transfer member. The distal end of the tubular transfer member includes a Luer lock for establishing fluid communication to a syringe, IV set or the like. An annular lip on the proximate end of the tubular transfer member stretches and prestresses the central portion of the planar stopper rim and the piercing member is supported in the transferset such that the piercing end deforms the prestressed stopper rim portion.

    摘要翻译: 本发明涉及一种改进的小瓶转移组件或小瓶传输组件,其可在无菌条件下连接到小瓶并用于将流体传送到常规小瓶或从常规小瓶传送流体。 传输组件包括密封地支撑在小瓶塞的边缘部分上的管状传送构件,具有由传送构件的内表面往复地支承的穿刺端的穿孔构件,封闭管状传送构件的盖子和优选地形成 一种可延展的材料,其将组件固定在塞子上,该塞子被压接在小瓶边缘下方。 刺穿构件具有大致纵向的外部通道,其在穿过止动件的平面部分时通过管状转移构件建立与小瓶的流体连通。 管状转移构件的远端包括用于建立与注射器,IV套等的流体连通的Luer锁。 管状转移构件的近端上的环形唇缘延伸并预应力于平面止动件边缘的中心部分,并且刺穿构件支撑在转移组件​​中,使得穿孔端使预应力止动件边缘部分变形。

    Vial transferset and method
    9.
    发明授权
    Vial transferset and method 有权
    样品瓶转移和方法

    公开(公告)号:US06189580B1

    公开(公告)日:2001-02-20

    申请号:US09454453

    申请日:1999-12-06

    IPC分类号: B65B104

    摘要: The improved vial transfer assembly or vial transferset may be attached to a vial under sterile conditions and used to transfer fluid to or from a conventional vial. The transferset includes a tubular transfer member which is sealingly supported on the rim portion of a vial stopper, a piercing member having a piercing end reciprocally supported by an internal surface of the transfer member, a cap enclosing the tubular transfer member and a collar preferably formed of a malleable material which secures the assembly on the stopper, which is crimped beneath the vial rim. The piercing member has a generally longitudinal external channel which, upon piercing the planar portion of the stopper, establishes fluid communication with the vial through the tubular transfer member. The distal end of the tubular transfer member includes a Luer lock for establishing fluid communication to a syringe, IV set or the like. An annular lip on the proximate end of the tubular transfer member stretches and prestresses the central portion of the planar stopper rim and the piercing member is supported in the transferset such that the piercing end deforms the prestressed stopper rim portion.

    摘要翻译: 改进的小瓶传送组件或小瓶传输组可以在无菌条件下连接到小瓶,并用于将流体传送到常规小瓶或从常规小瓶传送流体。 传输组件包括密封地支撑在小瓶塞的边缘部分上的管状传送构件,具有由传送构件的内表面往复地支承的穿刺端的穿孔构件,封闭管状传送构件的盖子和优选地形成 一种可延展的材料,其将组件固定在塞子上,该塞子被压接在小瓶边缘下方。 刺穿构件具有大致纵向的外部通道,其在穿过止动件的平面部分时通过管状转移构件建立与小瓶的流体连通。 管状转移构件的远端包括用于建立与注射器,IV套等的流体连通的Luer锁。 管状转移构件的近端上的环形唇缘延伸并预应力于平面止动件边缘的中心部分,并且刺穿构件支撑在转移组件​​中,使得穿孔端使预应力止动件边缘部分变形。

    Connector assembly for a vial having a flexible collar
    10.
    发明授权
    Connector assembly for a vial having a flexible collar 失效
    用于具有柔性套环的小瓶的连接器组件

    公开(公告)号:US6090093A

    公开(公告)日:2000-07-18

    申请号:US938441

    申请日:1997-09-25

    摘要: A connector assembly for a vial is disclosed. The connector assembly features a protective cap, a collar attachable to the rim of the vial, and a crimp cap for securing the collar to the rim. The collar features a flexible skirt provided adjacent the proximal end of the collar that is foldable about the underside portion of the vial rim. One or more ribs are provided adjacent a distal portion of the collar to seal against the stopper obturating the vial. The crimp cap can be supplied preattached to the collar in an uncrimped condition. When crimped, the crimp cap exerts a force against the distal end of the collar and the flexible skirt folded about the rim to secure the collar to the vial. A vial access device is contained within the collar

    摘要翻译: 公开了用于小瓶的连接器组件。 连接器组件具有保护帽,可附接到小瓶的边缘的套环以及用于将套环固定到边缘的压接帽。 衣领具有靠近衣领的近端提供的柔性裙部,其围绕小瓶边缘的下侧可折叠。 一个或多个肋设置在颈圈的远端部分附近,以密封堵塞小瓶的塞子。 卷边帽可以在未卷曲的状态下预先附着在衣领上。 当卷曲时,卷边帽对于衣领的远端施加力,并且柔性裙部围绕边缘折叠以将衣领固定到小瓶。 套管内装有小瓶检修装置