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公开(公告)号:US07332494B2
公开(公告)日:2008-02-19
申请号:US10075673
申请日:2002-02-13
申请人: J. Guy Breitenbucher , Hui Cai , James P. Edwards , Cheryl A. Grice , Yin Gu , Darin J. Gustin , Lars Karlsson , Haripada Khatuya , Steven P. Meduna , Barbara A. Pio , Siquan Sun , Kevin L. Tays , Robin L. Thurmond , Jianmei Wei
发明人: J. Guy Breitenbucher , Hui Cai , James P. Edwards , Cheryl A. Grice , Yin Gu , Darin J. Gustin , Lars Karlsson , Haripada Khatuya , Steven P. Meduna , Barbara A. Pio , Siquan Sun , Kevin L. Tays , Robin L. Thurmond , Jianmei Wei
IPC分类号: A61K31/497 , A61K31/50 , A61K31/53 , A61K31/505
CPC分类号: C07D231/12 , C07D471/04
摘要: A method for treating an allergic condition, including an atopic allergic condition, using substituted pyrazoles.
摘要翻译: 一种使用取代的吡唑治疗过敏性疾病(包括特应性过敏症状)的方法。
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公开(公告)号:US06579896B2
公开(公告)日:2003-06-17
申请号:US09946713
申请日:2001-09-05
申请人: Hui Cai , James P. Edwards , Yin Gu , Lars Karlsson , Steven P. Meduna , Barbara A. Pio , Siquan Sun , Robin L. Thurmond , Jianmei Wei
发明人: Hui Cai , James P. Edwards , Yin Gu , Lars Karlsson , Steven P. Meduna , Barbara A. Pio , Siquan Sun , Robin L. Thurmond , Jianmei Wei
IPC分类号: A61K31415
CPC分类号: A61K31/4745 , A61K31/00 , A61K31/13 , A61K31/275 , A61K31/4155 , A61K31/4439 , A61K31/454 , A61K31/495 , A61K31/496 , A61K31/519 , A61K31/53 , A61K31/5377 , A61K31/541 , A61K31/55
摘要: A method for the treatment of an allergic condition, including an an atopic allergic conditions, using substituted pyrazoles.
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公开(公告)号:US06583155B2
公开(公告)日:2003-06-24
申请号:US10075692
申请日:2002-02-13
申请人: Christopher R. Butler , Hui Cai , James P. Edwards , Cheryl A. Grice , Yin Gu , Darin J. Gustin , Lars Karlsson , Haripada Khatuya , Steven P. Meduna , Barbara A. Pio , Clark A. Sehon , Siquan Sun , Kevin L. Tays , Robin L. Thurmond , Jianmei Wei
发明人: Christopher R. Butler , Hui Cai , James P. Edwards , Cheryl A. Grice , Yin Gu , Darin J. Gustin , Lars Karlsson , Haripada Khatuya , Steven P. Meduna , Barbara A. Pio , Clark A. Sehon , Siquan Sun , Kevin L. Tays , Robin L. Thurmond , Jianmei Wei
IPC分类号: A61K3144
CPC分类号: A61K31/4745 , A61K31/00 , A61K31/13 , A61K31/275 , A61K31/4155 , A61K31/4439 , A61K31/454 , A61K31/495 , A61K31/496 , A61K31/519 , A61K31/53 , A61K31/5377 , A61K31/541 , A61K31/55
摘要: A method for treating an allergic condition, including an atopic allergic condition, using substituted pyrazoles.
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公开(公告)号:US06951851B2
公开(公告)日:2005-10-04
申请号:US10402696
申请日:2003-03-28
申请人: Hui Cai , James P. Edwards , Steven P. Meduna , Barbara A. Pio , Jianmei Wei
发明人: Hui Cai , James P. Edwards , Steven P. Meduna , Barbara A. Pio , Jianmei Wei
IPC分类号: A61K31/275 , A61K31/4155 , A61K31/437 , A61K31/4439 , A61K31/454 , A61K31/495 , A61K31/55 , A61P11/06 , A61P19/02 , A61P29/00 , A61P37/06 , C07D413/14 , C07D471/04 , C07D471/14 , C07D519/00 , C07D487/04 , A61K31/53
CPC分类号: C07D413/14 , A61K31/275 , A61K31/4155 , A61K31/4439 , A61K31/454 , A61K31/495 , A61K31/55 , C07D401/14 , C07D409/14 , C07D471/04 , C07D471/14
摘要: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S are described.
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公开(公告)号:US06635633B2
公开(公告)日:2003-10-21
申请号:US09927188
申请日:2001-08-10
申请人: Hui Cai , James P. Edwards , Steven P. Meduna , Barbara A. Pio , Jianmei Wei
发明人: Hui Cai , James P. Edwards , Steven P. Meduna , Barbara A. Pio , Jianmei Wei
IPC分类号: C07D48704
CPC分类号: C07D413/14 , A61K31/275 , A61K31/4155 , A61K31/4439 , A61K31/454 , A61K31/495 , A61K31/55 , C07D401/14 , C07D409/14 , C07D471/04 , C07D471/14
摘要: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S are described.
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公开(公告)号:US07429591B2
公开(公告)日:2008-09-30
申请号:US11517518
申请日:2006-09-07
申请人: Mary Pat Beavers , J. Guy Breitenbucher , Hui Cai , James P. Edwards , Cheryl A. Grice , Darin J. Gustin , Haripada Khatuya , Steven P. Meduna , Barbara A. Pio , Kevin L. Tays , Jianmei Wei
发明人: Mary Pat Beavers , J. Guy Breitenbucher , Hui Cai , James P. Edwards , Cheryl A. Grice , Darin J. Gustin , Haripada Khatuya , Steven P. Meduna , Barbara A. Pio , Kevin L. Tays , Jianmei Wei
IPC分类号: A61K31/497 , C07D403/12
CPC分类号: C07D231/12 , C07D471/04
摘要: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
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公开(公告)号:US07417046B2
公开(公告)日:2008-08-26
申请号:US11517145
申请日:2006-09-07
申请人: Mary Pat Beavers , J. Guy Breitenbucher , Hui Cai , James P. Edwards , Cheryl A. Grice , Darin J. Gustin , Haripada Khatuya , Steven P. Meduna , Barbara A. Pio , Kevin L. Tays , Jianmei Wei
发明人: Mary Pat Beavers , J. Guy Breitenbucher , Hui Cai , James P. Edwards , Cheryl A. Grice , Darin J. Gustin , Haripada Khatuya , Steven P. Meduna , Barbara A. Pio , Kevin L. Tays , Jianmei Wei
IPC分类号: A61K31/497 , C07D401/14 , C07D413/14 , C07D403/14
CPC分类号: C07D231/12 , C07D471/04
摘要: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
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公开(公告)号:US07589202B2
公开(公告)日:2009-09-15
申请号:US11517062
申请日:2006-09-07
申请人: Mary Pat Beavers , J. Guy Breitenbucher , Hui Cai , James P. Edwards , Cheryl A. Grice , Darin J. Gustin , Haripada Khatuya , Steven P. Meduna , Barbara A. Pio , Kevin L. Tays , Jianmei Wei
发明人: Mary Pat Beavers , J. Guy Breitenbucher , Hui Cai , James P. Edwards , Cheryl A. Grice , Darin J. Gustin , Haripada Khatuya , Steven P. Meduna , Barbara A. Pio , Kevin L. Tays , Jianmei Wei
IPC分类号: C07D403/06
CPC分类号: C07D231/12 , C07D471/04
摘要: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
摘要翻译: 取代的吡唑,其制备方法,含有它们的组合物,以及使用它们来治疗例如由组织蛋白酶S介导的自身免疫性疾病的方法。
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公开(公告)号:US20080300255A1
公开(公告)日:2008-12-04
申请号:US12220516
申请日:2008-07-24
申请人: Mary Pat Beavers , J. Guy Breitenbucher , Hui Cai , James P. Edwards , Cheryl A. Grice , Darin J. Gustin , Haripada Khatuya , Steven P. Meduna , Barbara A. Pio , Kevin L. Tays , Jianmei Wei
发明人: Mary Pat Beavers , J. Guy Breitenbucher , Hui Cai , James P. Edwards , Cheryl A. Grice , Darin J. Gustin , Haripada Khatuya , Steven P. Meduna , Barbara A. Pio , Kevin L. Tays , Jianmei Wei
IPC分类号: A61K31/497 , A61P37/00
CPC分类号: C07D231/12 , C07D471/04
摘要: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
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公开(公告)号:US20080293732A1
公开(公告)日:2008-11-27
申请号:US12220539
申请日:2008-07-24
申请人: Mary Pat Beavers , J. Guy Breitenbucher , Hui Cai , James P. Edwards , Cheryl A. Grice , Darin J. Gustin , Haripada Khatuya , Steven P. Meduna , Barbara A. Pio , Kevin L. Tays , Jianmei Wei
发明人: Mary Pat Beavers , J. Guy Breitenbucher , Hui Cai , James P. Edwards , Cheryl A. Grice , Darin J. Gustin , Haripada Khatuya , Steven P. Meduna , Barbara A. Pio , Kevin L. Tays , Jianmei Wei
IPC分类号: A61K31/496 , A61P37/00
CPC分类号: C07D231/12 , C07D471/04
摘要: Substituted pyrazoles, methods of manufacturing them, compositions containing them, and methods of using them to treat, for example, autoimmune diseases mediated by cathepsin S.
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