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公开(公告)号:US20210040150A1
公开(公告)日:2021-02-11
申请号:US16988229
申请日:2020-08-07
发明人: Subo Liao , Jun Yang , Jinliang Lv , Zongquan Liao , Hao Zhou , Jueyuan Gao , Tianpeng Xie , Quanli Yang , Lei Wang , Zejian Ding
IPC分类号: C07K5/107
摘要: The present invention provides kappa opioid receptor peptide agonists, methods for preparing these compounds, compositions comprising these kappa opioid receptor peptide agonists, and methods of using the kappa opioid receptor peptide agonists to treat pain or other conditions.
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公开(公告)号:US11214577B2
公开(公告)日:2022-01-04
申请号:US16834449
申请日:2020-03-30
发明人: Subo Liao , Jun Yang , Jie Li , Wentao Du , Lie Li , Jinliang Lv , Zongquan Liao , Hao Zhou , Tianpeng Xie , Jianbo Yu
IPC分类号: C07D491/08
摘要: The present invention related to novel morphinans, compositions comprising the novel morphinans, and their uses as agonists of the kappa opioid receptor.
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公开(公告)号:US20210403505A1
公开(公告)日:2021-12-30
申请号:US16911701
申请日:2020-06-25
发明人: Subo Liao , Jun Yang , Jinliang Lv , Zongquan Liao , Hao Zhou , Jueyuan Gao , Tianpeng Xie , Quanli Yang
摘要: The present invention provides compounds which are selective kappa-opioid receptor agonist, method of preparation of these compounds, compositions that comprise these compounds, and methods for treating kappa-opiod receptor agonist related medical disorders
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公开(公告)号:US11492374B2
公开(公告)日:2022-11-08
申请号:US16911701
申请日:2020-06-25
发明人: Subo Liao , Jun Yang , Jinliang Lv , Zongquan Liao , Hao Zhou , Jueyuan Gao , Tianpeng Xie , Quanli Yang
摘要: The present invention provides compounds which are selective kappa-opioid receptor agonist, method of preparation of these compounds, compositions that comprise these compounds, and methods for treating kappa-opiod receptor agonist related medical disorders.
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公开(公告)号:US20200308185A1
公开(公告)日:2020-10-01
申请号:US16834449
申请日:2020-03-30
发明人: Subo Liao , Jun Yang , Jie Li , Wentao Du , Lie Li , Jinliang Lv , Zongquan Liao , Hao Zhou , Tianpeng Xie , Jianbo Yu
IPC分类号: C07D491/08
摘要: The present invention related to novel morphinans, compositions comprising the novel morphinans, and their uses as agonists of the kappa opioid receptor.
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公开(公告)号:US20220354923A1
公开(公告)日:2022-11-10
申请号:US17862086
申请日:2022-07-11
发明人: Subo Liao , Jun Yang , Jinliang Lv , Zongquan Liao , Hao Zhou , Jueyuan Gao , Tianpeng Xie , Quanli Yang , Yao He , Dali Liang , Rong Liu
IPC分类号: A61K38/07
摘要: The present invention provides compounds which are selective kappa-opioid receptor agonist, method of preparation of these compounds, compositions that comprise these compounds, and methods for treating kappa-opiod receptor agonist related medical disorders.
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公开(公告)号:US20220089605A1
公开(公告)日:2022-03-24
申请号:US17538197
申请日:2021-11-30
发明人: Subo Liao , Jun Yang , Jie Li , Wentao Du , Lie Li , Jinliang Lv , Zongquan Liao , Hao Zhou , Tianpeng Xie , Jianbo Yu
IPC分类号: C07D491/08
摘要: The present invention related to novel morphinans, compositions comprising the novel morphinans, and their uses as agonists of the kappa opioid receptor.
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公开(公告)号:US20190054024A1
公开(公告)日:2019-02-21
申请号:US15678923
申请日:2017-08-16
发明人: Jun Yang , Yunqi Wu , Dunxi Chen , Cuiying Zhang , Yuping Yang , Longmei Qu , Lie Li , Jie Li , Wentao Du , Yigang Fu
摘要: A solid pharmaceutical dosage form having drug-loaded particles and methods of making.
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