COMPOSITION COMPRISING EUPATORIUM SPP. EXTRACT AS ACTIVE INGREDIENT FOR PREVENTING AND TREATING OBESITY AND METABOLIC BONE DISEASE
    1.
    发明申请
    COMPOSITION COMPRISING EUPATORIUM SPP. EXTRACT AS ACTIVE INGREDIENT FOR PREVENTING AND TREATING OBESITY AND METABOLIC BONE DISEASE 审中-公开
    包含EUPATORIUM SPP的组合物。 提取物作为预防和治疗肥胖和代谢性骨髓疾病的主要成分

    公开(公告)号:US20150157675A1

    公开(公告)日:2015-06-11

    申请号:US14389957

    申请日:2012-04-02

    摘要: The present invention relates to a Eupatorium spp. extract having anti-obesity effects as a result of decreasing adipocytes and increasing osteoblasts, as well as the effects of preventing bone disease or fractures by increasing osteoblasts and of preventing osteoporosis by decreasing adipocytes and increasing osteoblasts by the same proportion in mesenchymal stem cells. DCM fraction layers of a Eupatorium spp. stem extract collected on a monthly basis and Eupatorium spp. stem extract collected only in September may inhibit the activity of PPARγ, AP2, CD36, adiponectin C/EBPα, and LPL, which serve as significant factors for adipocyte differentiation in C3H10T1/2 cells and primary mesenchymal stem cells, which are pluripotent stem cell lines, and may increase the activity of ALP, osterix, CO1I and RUNX2, which serve as significant factors for osteoblast differentiation. The Eupatorium spp. extract of the present invention exhibits the effects of increasing bone mineral density (BMD) and decreasing adipocytes in bone marrow in an osteoporosis animal model experiment involving an ovariectomy, and therefore may be used as a useful material for preventing and treating osteoporosis.

    摘要翻译: 本发明涉及一种番茄属(Eupatorium spp。) 提取物具有作为脂肪细胞减少和成骨细胞增加的结果的抗肥胖效果,以及通过增加成骨细胞并通过减少脂肪细胞并在间充质干细胞中以相同比例增加成骨细胞来预防骨质疏松症来预防骨质疏松症的效果。 紫杉属的DCM级分层。 每月收集茎提取物和紫茎泽兰属 仅在9月份收集的茎提取物可能抑制PPARγ,AP2,CD36,脂联素C /EBPα和LPL的活性,其作为C3H10T1 / 2细胞和原代间充质干细胞的脂肪细胞分化的重要因子,其为多能干细胞系 ,并且可能增加ALP,osterix,CO1I和RUNX2的活性,其作为成骨细胞分化的重要因素。 紫ium属 本发明的提取物在涉及卵巢切除术的骨质疏松动物模型实验中表现出增加骨矿物质密度(BMD)和减少骨髓中的脂肪细胞的作用,因此可用作预防和治疗骨质疏松症的有用材料。

    MOBILE TERMINAL
    2.
    发明申请
    MOBILE TERMINAL 有权
    移动终端

    公开(公告)号:US20120329526A1

    公开(公告)日:2012-12-27

    申请号:US13432912

    申请日:2012-03-28

    IPC分类号: H04W88/02

    摘要: A mobile terminal is provided. The mobile terminal includes a terminal main body having a display module to display visual information, a window disposed above the display module and having a pattern layer to recognize a user's touch input, a key region formed on one surface of the window near one side thereof, and a light emitting module configured to illuminate the key region.

    摘要翻译: 提供移动终端。 移动终端包括终端主体,其具有显示视觉信息的显示模块,设置在显示模块上方的窗口,具有识别用户的触摸输入的图案层,形成在窗口的一侧的一个表面上的键区域 以及被配置为照亮所述键区域的发光模块。

    Mobile terminal
    4.
    发明授权
    Mobile terminal 有权
    移动终端

    公开(公告)号:US09392087B2

    公开(公告)日:2016-07-12

    申请号:US13432912

    申请日:2012-03-28

    摘要: A mobile terminal is provided. The mobile terminal includes a terminal main body having a display module to display visual information, a window disposed above the display module and having a pattern layer to recognize a user's touch input, a key region formed on one surface of the window near one side thereof, and a light emitting module configured to illuminate the key region.

    摘要翻译: 提供移动终端。 移动终端包括具有显示视觉信息的显示模块的终端主体,设置在显示模块上方的窗口,具有用于识别用户的触摸输入的图案层,形成在窗口的靠近其一侧的窗口的一个表面上的键区域 以及被配置为照亮所述键区域的发光模块。