公开(公告)号：US11567060B2

公开(公告)日：2023-01-31

申请号：US16624567

申请日：2018-06-19

申请人： ILLUMINA, INC.

发明人： Boyan Boyanov ,  Rohan N. Akolkar ,  Jeffrey S. Fisher ,  Jeffrey G. Mandell ,  Liangliang Qiang ,  Steven M. Barnard

IPC分类号： G01N33/487 ,  C12Q1/6869 ,  G01N27/447

摘要： Example nanopore sequencers include a cis well, a trans well, and a nanopore fluidically connecting the cis and trans wells. In one example sequencer, a modified electrolyte (including an electrolyte and a cation complexing agent) is present in the cis well, or the trans well, or in the cis and the trans wells. In another example sequencer, a gel state polyelectrolyte is present in the cis well, or the trans well, or in the cis and the trans wells.