专利检索 ap:("IMAGO PHARMACEUTICALS, INC.") AND inv:"Dean R. Artis" 第 1 页

1.

发明申请
SPIROCYCLIC DIHYDRO-THIAZINE AND DIHYDRO-OXAZINE BACE INHIBITORS, AND COMPOSITIONS AND USES THEREOF 审中-公开

公开(公告)号：US20160272654A1

公开(公告)日：2016-09-22

申请号：US15169978

申请日：2016-06-01

申请人： IMAGO PHARMACEUTICALS, INC.

发明人： Ying-Zi XU , Dean R. Artis , Simeon Bowers , Roy K. Hom , Hing L. Sham , Shendong Yuan

IPC分类号： C07D513/10 , C07D417/12 , C07D417/14 , C07D279/08

CPC分类号： C07D513/10 , C07D265/12 , C07D265/18 , C07D279/08 , C07D279/16 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D498/10

摘要： Compounds are provided having a structure according to Formula (I): wherein A1, A2, A3, Y, R1, R2, R3, R4, R5, R6, m, n and p are defined herein. Further provided are pharmaceutical compositions including the compounds provided and methods of making and using the compounds and compositions as provided, e.g., in the treatment and prevention of various disorders, such as Alzheimer's disease.

2.

发明授权
Spirocyclic dihydro-thiazine and dihydro-oxazine BACE inhibitors, and compositions and uses thereof 有权
标题翻译：螺环二氢 - 噻嗪和二氢恶嗪BACE抑制剂及其组合物和用途

公开(公告)号：US09493485B2

公开(公告)日：2016-11-15

申请号：US14386722

申请日：2013-03-20

申请人： Imago Pharmaceuticals, Inc.

发明人： Ying-Zi Xu , Dean R. Artis , Simeon Bowers , Roy K. Hom , Hing L. Sham , Shendong Yuan

IPC分类号： C07D513/10 , C07D417/12 , C07D413/14 , C07D413/10 , C07D413/12 , C07D265/12 , C07D265/18 , C07D498/10 , C07D279/16

CPC分类号： C07D513/10 , C07D265/12 , C07D265/18 , C07D279/08 , C07D279/16 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D498/10

摘要： Compounds are provided having a structure according to Formula (I): wherein A1, A2, A3, Y, R1, R2, R3, R4, R5, R6, m, n and p are defined herein. Further provided are pharmaceutical compositions including the compounds provided and methods of making and using the compounds and compositions as provided, e.g., in the treatment and prevention of various disorders, such as Alzheimer's disease.