Surface immobilization of an analyte-recognizing molecule

    公开(公告)号:US10746731B2

    公开(公告)日:2020-08-18

    申请号:US15577311

    申请日:2016-06-28

    Applicant: IMEC VZW

    Abstract: A method for immobilizing an analyte-recognizing molecule (1) on a surface (2′) functionalized with chemical groups Y1 suitable for reacting with a chemical group X2 of a coupling molecule (7) to form a reaction product comprising a chemical group Y2 suitable for reacting with the analyte-recognizing molecule (1), the method comprising the steps of: a) Providing the functionalized surface (2′), b) Contacting the functionalized surface (2′) with a solution (6) comprising simultaneously: i) The coupling molecule (7), and ii) The analyte-recognizing molecule (1).

    Cyclic Capillary Electrophoresis Device

    公开(公告)号:US20210080427A1

    公开(公告)日:2021-03-18

    申请号:US17018368

    申请日:2020-09-11

    Abstract: A cyclic capillary electrophoresis device includes a capillary channel that forms a closed loop. The capillary channel comprises an inner half facing toward a space enclosed by the loop, where the inner half having an inner wall of first charge density, and an outer half facing away from the space enclosed by the loop, where the outer half having an inner wall surface of second charge density. A difference between the first and the second charge densities exists or can be turned on. The difference is configured to create a smaller average electroosmotic flow velocity in the inner half than in the outer half.

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