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1.
公开(公告)号:US20230292743A1
公开(公告)日:2023-09-21
申请号:US18322906
申请日:2023-05-24
申请人: IMV TECHNOLOGIES , UNIVERSITE GRENOBLE ALPES , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , SWISSGENETICS
IPC分类号: A01N1/02 , A61D19/02 , A61K31/14 , A61K31/4748
CPC分类号: A01N1/0226 , A01N1/0221 , A61D19/024 , A61D19/027 , A61K31/14 , A61K31/4748
摘要: The invention relates to a method for increasing the lifespan of animal sperm comprising contacting said sperm with an inhibitor of Slo3 potassium channel.
The invention also relates to a use of an inhibitor of Slo3 potassium channel, for increasing the lifespan of animal sperm or motility of capacitated animal sperm, comprising contacting an inhibitor of Slo3 potassium channel with said sperm. Moreover, the invention relates to an artificial insemination instrument for use in artificial insemination of an animal, comprising animal sperm in contact with an inhibitor of Slo3 potassium channel.
The invention also relates to a method for artificially inseminating an animal using said artificial insemination instrument.
Eventually, the invention relates to a method for increasing the fertility of an animal, comprising contacting sperm of said animal with an inhibitor of Slo3 potassium channel; then artificially inseminating said animal with said sperm.-
2.
公开(公告)号:US20200315164A1
公开(公告)日:2020-10-08
申请号:US16955539
申请日:2018-12-18
申请人: IMV TECHNOLOGIES , UNIVERSITE GRENOBLE ALPES , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) , SWISSGENETICS
IPC分类号: A01N1/02 , A61D19/02 , A61K31/14 , A61K31/4748
摘要: The invention relates to a method for increasing the lifespan of animal sperm comprising contacting said sperm with an inhibitor of Slo3 potassium channel. The invention also relates to a use of an inhibitor of Slo3 potassium channel, for increasing the lifespan of animal sperm or motility of capacitated animal sperm, comprising contacting an inhibitor of Slo3 potassium channel with said sperm. Moreover, the invention relates to an artificial insemination instrument for use in artificial insemination of an animal, comprising animal sperm in contact with an inhibitor of Slo3 potassium channel. The invention also relates to a method for artificially inseminating an animal using said artificial insemination instrument. Eventually, the invention relates to a method for increasing the fertility of an animal, comprising contacting sperm of said animal with an inhibitor of Slo3 potassium channel; then artificially inseminating said animal with said sperm.
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公开(公告)号:US20220322659A1
公开(公告)日:2022-10-13
申请号:US17640002
申请日:2020-09-09
申请人: IMV TECHNOLOGIES
摘要: A support element for a plurality of packaging straws, the support element comprising a plate (31) and two flanges (37) rigidly connected to said plate (31) and comprising a fluted surface (53) having a plurality of similar grooves (36), each flange (37) comprising a central part as well as a first projecting part (42) and a second projecting part (43), each extending from one side of the central part, characterised in that the first projecting part comprises a bracket (42) having a bearing face and the second projecting part comprises another bracket (43) having another bearing face, said bearing face and said other bearing face being upwards facing and, in the direction of height, said bearing face being further from said plate (31) than said other bearing face. The assembly comprises the support element and a freezing rack (4).
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公开(公告)号:US20170196669A1
公开(公告)日:2017-07-13
申请号:US15314350
申请日:2015-05-27
申请人: IMV TECHNOLOGIES
发明人: Eric SCHMITT
CPC分类号: A61D19/024 , A01N1/02 , A01N1/0268 , A61D19/00 , A61D19/02 , A61D19/04 , A61K35/52
摘要: The straw comprises a tube (11) extending between a first end and a second end and comprises a gas-permeable, liquid-tight plug, said plug being arranged in the tube (11) in the vicinity of the first end of same and extending between a first end turned towards the first end of the tube (11) and a second end turned towards the second end of the tube (11). Said plug comprises an element (14) impregnated with multivalent cations (22) at least in the vicinity of a first end turned towards the second end of the tube (11). The system comprises the straw and a liquid medium provided to produce, by mixing, in predefined conditions, the liquid substance (21). The medium contains an alginate (23) in solution.
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公开(公告)号:US20210085169A1
公开(公告)日:2021-03-25
申请号:US16954781
申请日:2018-12-18
申请人: IMV TECHNOLOGIES
摘要: The appliance comprises a handle, a speculum tube (23) extending axially from the handle (21) as far as a distal end (22) where it has an opening (28), a video viewing system having a lens (35) arranged in the speculum tube and a transmission device (36) connected to the lens and connectable to a remote viewing screen, and a lens support (49) for keeping the lens (35) in a predetermined position with respect to the speculum tube, in which position the lens is near said opening (28) and opposite the space situated beyond said opening (28), characterized in that said speculum tube has an end part (26) and a main part (27) extending between said end part and said handle, said end part (26) being arranged around said support (49) and delimiting said opening (28), said end part (26) being elastically deformable and said main part (27) being rigid.
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6.
公开(公告)号:US20190151412A1
公开(公告)日:2019-05-23
申请号:US16306289
申请日:2017-06-01
申请人: IMV TECHNOLOGIES
CPC分类号: A61K38/1767 , A61K35/646 , A61P15/08 , C07K14/43522 , G01N33/5029 , G01N2333/43521
摘要: The invention relates to a La-1-like peptide agent that increases sperm motility. It is non-toxic and it may be used to treat male infertility in humans, and also to increase fertility in animals. It may be used in artificial reproductive techniques such as in vitro fertilisation (IVF), including intra-cytoplasmic sperm injection (ICSI). The La-1 like peptide agent may also be used in artificial insemination techniques such as intra-cytoplasmic uterine injection (IUI).
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7.
公开(公告)号:US20180271633A1
公开(公告)日:2018-09-27
申请号:US15928329
申请日:2018-03-22
申请人: IMV TECHNOLOGIES
发明人: Eric SCHMITT , Christian BEAU , Joël GROSOS , Ludovic LEFRANC
IPC分类号: A61D19/02
摘要: The installation (1) comprises a treatment machine (12) and a supply and positioning device (16) configured to receive the straws (2) and dispose them one by one in a predetermined orientation for their treatment by said machine. The device (16) comprises a curved ramp (52) having a reception portion (64) for the straws (2) and an ejection portion (65) for the straws, the ramp being configured to convey, to the ejection portion (65), a straw (2) received on the reception portion (64) and sliding on the ramp (52), the ramp having a concave profile such that said profile has an orientation closer to the vertical in the reception portion (64) than in the ejection portion (65), such that a straw received on the reception portion (64) is accelerated to the ejection portion (65) at which the straw is guided and ejected with a predetermined orientation.
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公开(公告)号:US20180162564A1
公开(公告)日:2018-06-14
申请号:US15578349
申请日:2016-06-02
申请人: IMV TECHNOLOGIES
发明人: Eric SCHMITT , Thierry LOUVIOT , Christian BEAU
CPC分类号: B65B1/16 , A61D19/024 , B67C3/26
摘要: The straw (11) filling device comprises a casing body having a cavity (43) in which the needle (9) of a nozzle (7) is placed. The needle is inserted into the straw tube (12) received in the cavity. The casing body is attached to a carriage separately from the needle. The cavity comprises a distal opening located on the distal end side of the needle, a proximal opening located on the proximal end side of the needle, and a longitudinal opening extending from the distal opening to the proximal opening, thus enabling placement and removal of the needle in and out of the cavity in a direction transverse to the direction of the needle and preventing an adult finger accessing the distal end of the needle. The machine comprises a device of this type and a conveyor (2) designed to keep the straw tube in a filling position during each cycle.
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公开(公告)号:US20200037606A1
公开(公告)日:2020-02-06
申请号:US16492426
申请日:2018-03-09
申请人: IMV TECHNOLOGIES
IPC分类号: A01N1/02
摘要: The invention concerns a cryogenic system (1) for vitrifying a substance comprising biological material to be preserved in a receiving region of a thin tube (8), comprising a tank (10) containing a bath (11) of a cryogenic agent and a support member (80) mounted on said tank in a predetermined first position in which said tube is orientated upright, the receiving region being immersed in a liquid zone (17) of said bath, and an opening of said tube being situated above said bath, in a zone of ambient air above said bath, in order to introduce the substance into the tube, the support member being mounted on said tank in a second predetermined position, in which said receiving region is immersed in the liquid zone and said opening is situated immediately above said liquid zone, in a gaseous zone (18) of said bath above said liquid zone and below said zone of ambient air, and being raised from said second position
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10.
公开(公告)号:US20180325642A1
公开(公告)日:2018-11-15
申请号:US15776482
申请日:2016-09-16
申请人: IMV TECHNOLOGIES
IPC分类号: A61D19/02
CPC分类号: A61D19/024 , B65B19/34
摘要: The invention relates to a storage receptacle (1) with a longitudinal opening (5) through which straws (2) for packing liquid-based substance are passed in a predetermined orientation of the straws, a housing (3) provided for the straws and configured to be inserted slidably in a cover (4) of the receptacle, the latter having an open configuration, in which the housing is partially inserted in the cover and the opening is free for the passage of the straws, and a closure configuration, in which the housing is inserted in the cover and the opening is closed by the cover in order to prohibit the passage of the straws. The housing has a parallelepipedal shape, a first front wall in which the opening is formed, a first bottom wall, two first longitudinal wails extending parallel to the opening, and two first side walls which each have two diagonals of a length less than or equal to the length of the straws.
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