CLOSE-LOOP DEEP BRAIN STIMULATION ALGORITHM SYSTEM FOR PARKINSON?S DISEASE AND CLOSE-LOOP DEEP BRAIN STIMULATION ALGORITHM METHOD FOR PARKINSON?S DISEASE

    公开(公告)号:US20240075291A1

    公开(公告)日:2024-03-07

    申请号:US18088777

    申请日:2022-12-27

    CPC classification number: A61N1/36067 A61N1/36139 A61N1/36178

    Abstract: A close-loop deep brain stimulation algorithm system for Parkinson's disease includes a memory and a processor. The processor includes a deep brain stimulation (DBS) simulation module, a virtual brain network module, a feature extraction module, and a reinforcement learning module. The deep brain stimulation simulation module is adapted to combine a deep brain stimulation waveform according to the stimulation frequency and the stimulation amplitude and output the deep brain stimulation waveform. The virtual brain network module is adapted to receive the deep brain stimulation waveform to output a synaptic signal and calculate a reward parameter. The feature extraction module is adapted to receive the synaptic signal and extract a plurality of feature values according to the synaptic signal. The reinforcement learning module is adapted to train a deep brain stimulation neural network based on the feature values and reward parameter and output the stimulation frequency and the stimulation amplitude to the deep brain stimulation simulation module.

    Neuromodulation probe
    4.
    发明授权

    公开(公告)号:US11794002B2

    公开(公告)日:2023-10-24

    申请号:US17546725

    申请日:2021-12-09

    CPC classification number: A61N1/0534

    Abstract: A neuromodulation probe includes a body and at least one coil set. The body has a first axis and a length along the first axis. The at least one coil set includes at least one coil, and the at least one coil is formed by winding spirally a conductive wire plural times about a second axis inside the body or on an outer surface of the body. The second axis is parallel to the first axis. The at least one coil has two opposite wire ends for providing an electric current to flow in or out of the at least one coil.

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