公开(公告)号：US20140179774A1

公开(公告)日：2014-06-26

申请号：US13727387

申请日：2012-12-26

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： Shau-Feng CHANG ,  Chun-Hsien MA ,  Kuo-Yi YANG

IPC: C07D407/10

CPC classification number: C07D407/10 ,  A61K31/353 ,  A61K36/185 ,  C07D311/62

Abstract: The present invention relates to methods of treating one or more symptoms of a SHC-1/p66-related disease, inhibiting ROS generation or for the manufacture of a medicament in the above-mentioned treatment.

Abstract translation: 本发明涉及在上述治疗中治疗SHC-1 / p66相关疾病的一个或多个症状，抑制ROS产生或制造药物的方法。

公开(公告)号：US20210338414A1

公开(公告)日：2021-11-04

申请号：US17243858

申请日：2021-04-29

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： Chih-Chieh HUANG ,  Jeng-Liang KUO ,  Hui-Ting HUANG ,  Shiun-Yin CHANG ,  Meng-Hsueh LIN ,  Cheng-Yi WU ,  Lih-Tao HSU ,  Pei-I TSAI ,  Hsin-Hsin SHEN ,  Chih-Yu CHEN ,  Kuo-Yi YANG ,  Chun-Hsien MA

IPC: A61F2/08

Abstract: A tissue repair device and a method for using the same are provided. The tissue repair device includes a body portion and at least one wire. The body portion includes an inner layer and an outer layer. The inner layer is close to a tissue, wherein the inner layer includes a hydrophilic structure, and the outer layer includes a hydrophobic structure. The wire is connected to the body portion to fix the body portion to the tissue.

公开(公告)号：US20210137699A1

公开(公告)日：2021-05-13

申请号：US16725481

申请日：2019-12-23

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： Fang-Jie JANG ,  Pei-I TSAI ,  Chih-Chieh HUANG ,  De-Yau LIN ,  Wei-Lun FAN ,  Yi-Hung WEN ,  Kuo-Yi YANG ,  Hsin-Hsin SHEN

IPC: A61F2/44 ,  A61F2/30

Abstract: The disclosure relates to a spinal intervertebral body fusion device including an adjustable spacer, a first and second pushing piece, and an operative piece. The adjustable spacer includes a first and second supporting plate. The first supporting plate portion is movably installed on the second supporting plate portion. The first and second supporting plate portions form a first and second opening respectively located at two opposite sides of the adjustable spacer. The first pushing piece located at the first opening and is partially clamped by the first and second supporting plate portions. The second pushing piece located at the second opening is partially clamped by the first and second supporting plate portions. The operative piece is movably disposed through the second pushing piece and screwed to the first pushing piece. The operative piece has an annular slot, and the second pushing piece is partially located in the annular slot.

公开(公告)号：US20220175432A1

公开(公告)日：2022-06-09

申请号：US17112573

申请日：2020-12-04

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： Hsin-Hsin SHEN ,  Pei-I TSAI ,  Kuo-Yi YANG ,  Fang-Jie JANG ,  An-Li CHEN ,  Shih-Ping LIN ,  Chih-Chieh HUANG ,  Yi-Hung WEN ,  Wei-Lun FAN ,  Shin-I HUANG

IPC: A61B17/86

Abstract: A bone screw includes an external screw thread, an internal supporter structure and a porous layer. The internal supporter structure is inside the external screw thread. The internal supporter structure includes a screw thread supporter or a polygonal wall supporter. The porous layer is on a surface of the internal supporter structure. Therefore, the bone screw has an increased strength and also provides postoperative healing effect.

公开(公告)号：US20190201061A1

公开(公告)日：2019-07-04

申请号：US15856774

申请日：2017-12-28

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE ,  National Taiwan University Hospital

Inventor： Pei-I TSAI ,  Hsin-Hsin SHEN ,  Kuo-Yi YANG ,  Shih-Ping LIN ,  Jui-Sheng SUN ,  Chih-Yu CHEN ,  Yu-Tsung CHIU ,  Chun-Ti CHEN ,  De-Yau LIN ,  An-Li CHEN

IPC: A61B17/72 ,  A61B17/74

CPC classification number: A61B17/7266 ,  A61B17/746 ,  A61B17/8805

Abstract: An expandable orthopedic implant includes a casing pipe, a shaft, a first expandable element and a first link lever. The casing pipe has a first opening, a second opening and an axis passing through the first and second opening. The casing pipe sheathes one end of the shaft, and the other end of the shaft has a top portion disposed out of the first opening. The first expandable element has a first terminal pivoted on the casing pipe and a second terminal. The first link lever has a proximal end pivoted to the top portion and a distal end pivoted to the second terminal. When the top portion is driven moving away from the first opening along an extending direction of the axis, the first link-lever can be pushed by the shaft to enact the second terminal moving away from the axis along a direction perpendicular to the axis.