公开(公告)号：US20230350181A1

公开(公告)日：2023-11-02

申请号：US17731182

申请日：2022-04-27

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： Sheng-Li CHANG ,  Chi Shen CHANG ,  Chih-Cheng HSU

IPC: G02B21/12 ,  G06V20/69 ,  G02B21/34

CPC classification number: G02B21/125 ,  G06V20/69 ,  G02B21/34

Abstract: A microscopic observation method configured to observe a specimen in a specimen carrier that includes the following steps: placing the specimen carrier at an observation point; obtaining a length of the specimen carrier along a movement direction, a thickness of the specimen carrier along an observation direction of a microscope objective, an observation angle of the microscope objective, and a relative distance between a lateral surface of the specimen carrier and the microscope objective along the movement direction; and adjusting an incident angle of a light beam emitted from a dark-field illumination towards the specimen carrier according to a calculation result of the length, the thickness, the observation angle, and the relative distance.

公开(公告)号：US20170193659A1

公开(公告)日：2017-07-06

申请号：US15395258

申请日：2016-12-30

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： Yen-Chang WANG ,  Chih-Ming CHENG ,  Chir-Weei CHANG ,  Chi-Shen CHANG ,  Sheng-Li CHANG

IPC: G06T7/00 ,  G06T7/13 ,  A61B5/00 ,  G06T7/90

CPC classification number: G06T7/0012 ,  A61B5/0066 ,  A61B5/441 ,  A61B8/0858 ,  A61B2576/02 ,  G06T7/12 ,  G06T2207/10101 ,  G06T2207/30088

Abstract: A method for evaluating skin tissue includes: obtaining a tomographic image of skin; performing a quantization process for quantizing brightness values of the tomographic image of skin to generate a quantized image; performing a binarization process on the brightness value of each image point in the quantized image according to a first threshold interval to generate a first filtered image; performing the binarization process on the brightness value of each image point in the quantized image according to a second threshold interval to generate a second filtered image; obtaining a first estimated tissue boundary according to the distribution of the bright spots in the first filtered image; obtaining a second estimated tissue boundary according to the distribution of the bright spots in the second filtered image; estimating a thickness of skin tissue according to a difference between the first and second estimated tissue boundaries.