公开(公告)号：US09682062B2

公开(公告)日：2017-06-20

申请号：US14133213

申请日：2013-12-18

Applicant: Industrial Technology Research Institute

Inventor： I-Horng Pan ,  Hsin-Jan Yao ,  Mei-Wei Lin ,  I-Huang Lu ,  Hsin-Chieh Wu ,  Hsiang-Wen Tseng ,  Ching-Huai Ko ,  Chun-Chung Wang ,  Zong-Keng Kuo ,  Shyh-Horng Lin ,  Yi-Cheng Cheng ,  Tien-Soung Tong

IPC: A61K36/15 ,  A61K36/185 ,  A61K31/365 ,  A61K36/14 ,  A61K31/7048

CPC classification number: A61K31/365 ,  A61K31/7048 ,  A61K36/14 ,  A61K2300/00

Abstract: The disclosure provides a pharmaceutical composition for inhibiting angiogenesis, including an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient. The pharmaceutical composition may further include a pharmaceutically acceptable carrier or salt. The disclosure also provides a method for inhibiting angiogenesis, including administering an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient for inhibiting angiogenesis to a subject in need thereof.

公开(公告)号：US10821148B2

公开(公告)日：2020-11-03

申请号：US15416391

申请日：2017-01-26

Applicant: Industrial Technology Research Institute

Inventor： Kuo-Kuei Huang ,  I-Horng Pan ,  Ying-Fei Tsai ,  I-Huang Lu ,  Chu-Hsun Lu ,  Shu-Fang Wen ,  Zong-Keng Kuo ,  Shu-Jiau Chiou

IPC: A61K36/00 ,  A61K36/75 ,  A61K31/395 ,  A61K31/366 ,  A61K31/37 ,  A61K31/4015 ,  A61K31/404

Abstract: The present disclosure provides a pharmaceutical composition for treating or alleviating an autoimmune disease and/or complication thereof and/or nephritis, including: an effective amount of an extract of a plant belonging to Rutaceae as an effective ingredient for treating or alleviating the autoimmune disease and/or complication thereof and/or nephritis, wherein the autoimmune disease is selected from a group consisting of lupus erythematosus, psoriasis, psoriatic arthritis, ankylosing spondylitis, rheumatoid arthritis, juvenile idiopathic arthritis, Crohn's disease and ulcerative colitis (UC).

公开(公告)号：US11701399B2

公开(公告)日：2023-07-18

申请号：US17138610

申请日：2020-12-30

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： I-Hong Pan ,  Kuei-Chang Li ,  Zong-Keng Kuo ,  Chu-Hsun Lu ,  Yen-Wu Hsieh ,  Shu-Fang Wen

IPC: A61K36/074 ,  A61K36/185 ,  A61K36/725 ,  A61P1/00 ,  A61K31/575 ,  A61P25/28 ,  A61P25/20 ,  A61K36/77

CPC classification number: A61K36/074 ,  A61K31/575 ,  A61K36/185 ,  A61K36/725 ,  A61K36/77 ,  A61P1/00 ,  A61P25/20 ,  A61P25/28

Abstract: A composition for modulating intestinal permeability and/or treating and/or preventing leaky gut related diseases including a Chinese herbal compound material or a Chinese herbal compound extract is provided. The Chinese herbal compound material includes Ganoderma, red jujube, longan and lotus seed. Moreover, the Chinese herbal compound extract includes a Ganoderma extract, a red jujube extract, a longan extract and a lotus seed extract.

公开(公告)号：US12226441B2

公开(公告)日：2025-02-18

申请号：US18327583

申请日：2023-06-01

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： I-Hong Pan ,  Kuei-Chang Li ,  Zong-Keng Kuo ,  Chu-Hsun Lu ,  Yen-Wu Hsieh ,  Shu-Fang Wen

IPC: A61K36/074 ,  A61K31/575 ,  A61K36/185 ,  A61K36/725 ,  A61K36/77 ,  A61P1/00 ,  A61P25/20 ,  A61P25/28

Abstract: A composition for inhibiting intestinal permeability, treating leaky gut related diseases and/or preventing leaky gut related diseases including a Chinese herbal compound material or a Chinese herbal compound extract is provided. The Chinese herbal compound material includes Ganoderma, red jujube, longan and lotus seed. Moreover, the Chinese herbal compound extract includes a Ganoderma extract, a red jujube extract, a longan extract and a lotus seed extract.