专利检索 ap:("INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE)" OR "UNIVERSITÉ PARIS DESCARTES" OR "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)" OR "FONDATION IMAGINE" OR "ASSISTANCE PUBLIQUE-HÔPITAUX DE PARIS (APHP)" OR "UNIVERSITÉ DE NANTES" OR "UNIVERSITÉ D'ANGERS" OR "CENTRE HOSPITALIER UNIVERSITAIRE D'ANGERS") AND inv:"Ivan CRUZ-MOURA" 第 1 页

1.

发明申请
METHODS FOR PREDICTING THE RESPONSIVENESS OF A PATIENT AFFECTED WITH MALIGNANT HEMATOLOGICAL DISEASE TO CHEMOTHERAPY TREATMENT AND METHODS OF TREATMENT OF SUCH DISEASE 审中-公开

公开(公告)号：US20180031579A1

公开(公告)日：2018-02-01

申请号：US15550394

申请日：2016-02-11

申请人： INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , UNIVERSITÉ PARIS DESCARTES , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) , FONDATION IMAGINE , ASSISTANCE PUBLIQUE-HÔPITAUX DE PARIS (APHP) , UNIVERSITÉ DE NANTES , UNIVERSITÉ D'ANGERS , CENTRE HOSPITALIER UNIVERSITAIRE D'ANGERS

发明人： Ivan CRUZ-MOURA , Valérie BARDET , Michaël DUSSIOT , Thiago TROVATI MACIEL , Jérôme TAMBURINI , Norbert IFRAH , Olivier HERMINE

IPC分类号： G01N33/74 , A61K39/395 , C07K16/22

CPC分类号： G01N33/74 , A61K39/3955 , C07K16/22 , C07K2317/76 , C12Q1/6886 , C12Q2600/106 , C12Q2600/158 , G01N33/57426 , G01N2333/475 , G01N2333/51 , G01N2800/22 , G01N2800/52

摘要： The present invention relates to antagonists of GDF11, for use in the treatment of malignant hematological disease, such as Acute Myeloid Leukemia (AML). The present invention also relates to a method for predicting the responsiveness of a patient affected with malignant haematological disease, such as Acute Myeloid Leukemia, to a chemotherapy treatment.