公开(公告)号：US20200306161A1

公开(公告)日：2020-10-01

申请号：US16763068

申请日：2018-11-08

申请人： ISP INVESTMENTS LLC

发明人： Philip John OTHS ,  Shafiq Sahar WAHIDI ,  Petros GEBRESELASSIE ,  Hani M. FARES

IPC分类号： A61K8/55 ,  A61K8/73 ,  A61K8/34 ,  A61K8/86 ,  A61Q11/00

摘要： A substantially anhydrous thickener system in the form of a gel for use in oral care compositions comprising: carboxymethyl cellulose or its salts thereof, a chelating agent, and hydroxyethyl cellulose, in a solvent system, wherein the thickener system is heated to a temperature ranging from about 70° C. to about 120° C. to form the gel. A method of preparing the thickener system for use in oral care compositions comprises the steps of: a) charging a mixture of hydroxyethyl cellulose and carboxymethyl cellulose into a reaction container, b) dissolving the mixture of a) in a solvent system, c) charging a chelating agent into b), and d) heating the resultant of c) to a temperature of 70°-120° C. for at least about 10 minutes.

公开(公告)号：US20220401395A1

公开(公告)日：2022-12-22

申请号：US17764511

申请日：2020-08-24

申请人： ISP INVESTMENTS LLC

发明人： Sounak SARKAR ,  Shafiq Sahar WAHIDI ,  Petros GERESELASSIE ,  Philip John OTHS ,  Hani M. FARES

IPC分类号： A61K31/194 ,  A61K31/79 ,  A61K31/717 ,  A61K45/06

摘要： A mucoadhesive composition including denture adhesive composition comprising: (i) 10 to about 75 wt. % of a maleic acid or anhydride copolymer; (ii) 10 to about 50 wt. % of a cellulose ether; (iii) 0.1 to 10 wt. % of a crosslinked polyvinyl pyrrolidone that is swellable but not soluble in water; and (iv) 30 to 70 wt. % of an orally acceptable carrier based on the total weight of the composition. Also disclosed is a method of use thereof and a process lot preparing the same.

公开(公告)号：US20230263712A1

公开(公告)日：2023-08-24

申请号：US18012373

申请日：2021-06-28

申请人： ISP INVESTMENTS LLC

发明人： Hani M. FARES ,  Yevgeniy TUROVSKIY ,  Solomon Howard JACOBSON ,  Philip John OTHS ,  Petros GEBRESELASSIE ,  Joseph TORELLA ,  Karen WINKOWSKI

IPC分类号： A61K8/35 ,  A61Q11/00

CPC分类号： A61K8/35 ,  A61Q11/00 ,  A61K2800/524 ,  A61K2800/92 ,  A61K2800/74

摘要： An oral care antimicrobial composition comprises about 0.1 to about 99.9 wt. % of at least one compound having the structure of




Also disclosed is a process for preparing the composition and methods of use thereof.

公开(公告)号：US20180346628A1

公开(公告)日：2018-12-06

申请号：US15777813

申请日：2016-11-14

申请人： ISP INVESTMENTS LLC

发明人： Philip John OTHS ,  Karyn B. VISSCHER ,  Fu CHEN ,  Petros GEBRESELASSIE ,  William E. PROSISE ,  Shafiq Sahar WAHIDI

IPC分类号： C08F220/36 ,  C08F220/28 ,  A61K8/81 ,  A61Q11/00 ,  A61Q11/02

摘要： The present invention provides a water-soluble or water-dispersible polymers. The water-soluble or water-dispersible polymer comprise a first monomer having hydrogen bonding/complexing properties to polyphenols, a second monomer having detergent properties, and a third monomer having hydrogen bonding/complexing properties to polyphenols, wherein the first monomer and the third monomer are the same or different. The present invention also provides oral care compositions comprising the water-soluble or water-dispersible polymers. The present invention also provides methods of cleaning, whitening and polishing natural teeth and dental prosthesis and of preventing, reducing or removing surface deposited stains from teeth by administering the oral care compositions. The water-soluble or water-dispersible polymer has a structure: wherein x, y, z, mole %, n, R1, and R2 are defined herein.