公开(公告)号：US20200246252A1

公开(公告)日：2020-08-06

申请号：US15776232

申请日：2016-11-10

Applicant: ISP INVESTMENTS LLC ,  ELC MANAGEMENT LLC

Inventor： Elodie OGER ,  Rachel CHABERT ,  Isabelle IMBERT ,  Jean-Marie BOTTO ,  Nouha DOMLOGE ,  Joel MANTELIN ,  Nadine PERNODET ,  Kelly DONG ,  Chia-Wen CHEN

IPC: A61K8/9794 ,  A61Q19/08 ,  A61Q17/04 ,  A61K8/60

Abstract: The invention relates to a topical composition comprising an extract of Tiger lily (Lilium tigrinum) enriched in low molecular weight RNA. The invention also relates to a method of cosmetic care including the topical application a composition comprising an extract of Tiger lily (Lilium tigrinum) in a physiologically acceptable medium, in order to reduce skin signs of aging and photo-aging. The invention is also directed to a cosmetic method of treatment to improve cell viability, to improve cell protection against particulate matter and against DNA damages, and to reduce cellular senescence.

公开(公告)号：US20190201321A1

公开(公告)日：2019-07-04

申请号：US16330020

申请日：2017-09-06

Applicant: ISP Investments LLC ,  ELC Management LLC

Inventor： Nadine PERNODET ,  Dawn LAYMAN ,  Jean-Marie BOTTO ,  Elodie OGER ,  Audrey LE MESTR ,  Isabelle IMBERT ,  Nouha DOMLOGE

IPC: A61K8/9789 ,  A61Q19/08 ,  A61Q17/04

Abstract: The present invention provides a process for obtaining an extract from peach flower extract (Primus persica L.) for skin cosmetic use, a peach flower extract obtainable by the process and a cosmetic composition comprising the said extract. The invention further provides a method for modulating the SIRT2 expression, a method of treatment designed to reduce and/or correct the signs of aging and photo-aging of the skin and keratinous appendages, and to protect the skin against aggressions due to ultraviolet radiation.

公开(公告)号：US20210259947A1

公开(公告)日：2021-08-26

申请号：US16973878

申请日：2019-06-14

Applicant: ISP INVESTMENTS LLC ,  SEACRET SPA LTD

Inventor： Elodie OGER ,  Isabelle IMBERT ,  Audrey LE MESTR ,  Rachel CHABERT ,  Isabelle AFRIAT STALOFF ,  Boaz YADIN

IPC: A61K8/9722 ,  C12N1/12 ,  A61K8/9728 ,  A61K8/60 ,  A61Q5/12

Abstract: Methods for obtaining an aqueous extract of a microalgae Dunaliella salina cultivated in the absence of light in a culture medium of a yeast extract, sugar and salt include solubilising a yeast extract in water then adding sugar and salt. After solubilisation of the salt and at a pH between 5 and 8, the microalgae Dunaliella salina is added with stirring, in darkness and at room temperature, for a fermentation period of at least 12 hours. After the fermentation period, grinding and filtering are performed to separate a soluble aqueous raw extract to which salt is added. This extract undergoes sterilising filtration with a porosity threshold of less than or equal to 0.2 μm and has a pH between 3.5 and 4.5. The extract obtained by the method, compositions incorporating the extract, and methods of skincare, scalp care and skin appendage care using such compositions are also disclosed.

公开(公告)号：US20180371000A1

公开(公告)日：2018-12-27

申请号：US15774754

申请日：2016-11-10

Applicant: ISP INVESTMENTS LLC

Inventor： Elodie OGER ,  Valerie LEQUOY ,  Frederique PORTOLAN

IPC: C07H1/08 ,  C07H21/02 ,  A61Q19/08 ,  A61Q19/00 ,  A61K8/44 ,  A61K8/60 ,  A61K8/9789 ,  A61K8/9794

Abstract: The invention relates to a method for obtaining an aqueous extract enriched with small RNA having a maximum length of 150 nucleotides, from plant material. The invention is characterized in that it comprises the following steps according to which: a) the plant material is put in contact with water; b) tetrasodium ethylenediaminetetraacetic acid (EDTA) is added to the mixture obtained in a) at a pH between 10.5 and 11; c) then, the pH of the mixture obtained in b) is adjusted to a value between 6 and 8; d) the mixture obtained in c) is purified in such a manner as to eliminate the plant material and to recover an aqueous raw extract; and e) the pH is checked and readjusted if necessary to a value between 6 and 8. The invention also relates to an aqueous extract of plant material, enriched with small RNAs having a maximum length of 150 nucleotides, which can be obtained by such a method, as well as to the compositions comprising such an extract and to their cosmetic uses for combating the signs of skin aging and for improving the hydration of the skin.

公开(公告)号：US20240374503A1

公开(公告)日：2024-11-14

申请号：US18291098

申请日：2022-07-19

Applicant: ISP Investments LLC

Inventor： Elodie OGER ,  Laura MOURET

IPC: A61K8/9789 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08

Abstract: The invention relates to an extract of black tea (Camellia sinensis) enriched in particular in small RNAs, sugars, phenolic compounds, amino acids and theanine, and to a process for preparing such an extract. The invention also relates to cosmetic compositions comprising such an extract, and to the uses of cosmetic compositions comprising a black tea extract from any source, with the exception of black tea from Mauritius, for caring for the skin, scalp and appendages, and more particularly for protecting the skin from external aggression and oxidation, combating the signs of skin ageing, increasing photoprotection, lightening the skin and improving skin hydration.

公开(公告)号：US20240009111A1

公开(公告)日：2024-01-11

申请号：US18035711

申请日：2021-11-23

Applicant: ISP INVESTMENTS LLC

Inventor： Elodie OGER ,  Laura MOURET

IPC: A61K8/9789 ,  A61K8/55 ,  A61K8/81 ,  A61Q19/08 ,  A61Q19/00

CPC classification number: A61K8/9789 ,  A61K8/55 ,  A61K8/8176 ,  A61Q19/08 ,  A61Q19/007 ,  A61K2800/805 ,  A61K2800/412

Abstract: The invention relates to a process for obtaining aqueous extracts of tea leaves (Camellia sinensis), in particular of leaves of fresh tea, pu'er tea, matcha tea or green tea. The invention also relates to tea extracts enriched with small RNAs, sugars, phenolic compounds, organic acids, theine and theanine, as well as to cosmetic compositions comprising such extracts and their cosmetic uses for the care of the skin, the scalp, and the appendages and more particularly for protecting the skin from external aggressions and oxidation, combating the signs of skin ageing, increasing photoprotection, lightening the skin and improving skin hydration.

公开(公告)号：US20230390182A1

公开(公告)日：2023-12-07

申请号：US17795389

申请日：2021-01-26

Applicant: ISP INVESTMENTS LLC.

Inventor： Elodie OGER ,  Catherine GONDRAN ,  Florian LABARRADE

IPC: A61K8/9789 ,  A61Q19/00

CPC classification number: A61K8/9789 ,  A61Q19/00 ,  A61K2800/10 ,  A61K2800/80

Abstract: The invention relates to a process for obtaining an aqueous extract of lavender enriched with small RNAs of a maximum length of 150 nucleotides, with sugars, with phenolic compounds, with organic acids and devoid of DNA, obtained by the following process: the lavender aerial parts are brought into contact with water; phytic acid is added at a pH of between 10 and 11; the pH of the mixture obtained is then adjusted to a value of between 6 and 8, the mixture obtained is purified. The invention also relates to cosmetic compositions comprising such an extract and their cosmetic uses for protecting the skin from external aggression and oxidation, combating the signs of skin ageing, increasing photoprotection, lightening the skin, improving hydration, reinforcing the barrier function, soothing the skin or improving the biological mechanisms associated with skin repair during the night.