公开(公告)号：US20250040541A1

公开(公告)日：2025-02-06

申请号：US18722364

申请日：2022-12-19

Applicant: ISP Investments LLC

Inventor： Hani M. FARES ,  Anthony ADAMO ,  Yevgeniy TUROVSKIY

IPC: A01N35/02 ,  A01P1/00 ,  A61K8/34 ,  A61K8/35 ,  A61Q17/00

Abstract: The present application provides an antibacterial liquid composition comprising: (a) from about 0.01 to about 99.8 wt. % of raspberry ketone having a structure of (I); (b) from about 0.1 to about 95% wt. % of one or more diols having a carbon chain length of from 3 to 12 atoms; and (c) from about 0.1 to about 95% wt. % of one or more compounds selected from the group consisting of phenoxyethanol, phenoxypropanol, phenylpropanol, phenethyl alcohol, veratryl alcohol, benzyl alcohol, 2-methyl-1-phenyl-2-propanol and combinations thereof. Also disclosed is a process for preparing the compositions and a method of use thereof.

公开(公告)号：US12098291B2

公开(公告)日：2024-09-24

申请号：US17282972

申请日：2019-10-07

Applicant: ISP INVESTMENTS LLC

Inventor： Kapish Karan ,  Ronald Hach ,  Stuart C. Porter

IPC: C09D101/04 ,  A61K9/28 ,  C08K5/11 ,  C09D7/61 ,  C09D7/63 ,  C09D7/65 ,  C09D105/02 ,  C09D131/04 ,  C09D139/06 ,  C08K3/22

CPC classification number: C09D101/04 ,  A61K9/282 ,  A61K9/284 ,  A61K9/2866 ,  C08K5/11 ,  C09D7/61 ,  C09D7/63 ,  C09D7/65 ,  C09D105/02 ,  C09D131/04 ,  C09D139/06 ,  C08K2003/2241

Abstract: The present application provides high solids film coating compositions comprising a water-soluble cellulose ether, hydroxy propyl cellulose (HPC), a poly (N-vinyl pyrrolidone-co-vinyl acetate) copolymer, a film-forming agent based on D-glucose, plasticizer, medium chain triglycerides (MCT) and an anti-tack agent. The invention further provides a process for preparing the above described film coating compositions and method of coating solid substrate with such coating compositions.

公开(公告)号：US20240225986A9

公开(公告)日：2024-07-11

申请号：US18022244

申请日：2021-08-20

Applicant: ISP INVESTMENTS LLC

Inventor： Feng LING ,  NING Ling ,  BU Tianyun

IPC: A61K8/65 ,  A61Q19/02 ,  A61Q19/08

CPC classification number: A61K8/65 ,  A61Q19/02 ,  A61Q19/08 ,  A61K2800/592

Abstract: The present invention relates to compositions and methods for improving the appearance of the skin. Compositions comprises at least water, glycerin, sodium PCA, erythritol, Carrageenan (Chondrus Crispus extract), xanthan Gum; hydrolyzed collagen, hexapeptide-9 and a physiologically acceptable medium. Methods comprise applying the compositions to the skin to improve the appearance of aging skin, increasing skin moisturization, refining skin pores and decreasing aging skin pigmentation defects.

公开(公告)号：US20240216256A1

公开(公告)日：2024-07-04

申请号：US18554377

申请日：2022-04-06

Applicant: ISP INVESTMENTS LLC

Inventor： Karine DERUDDRE ,  Marie-Aude Gidel SOURY-LAVERGNE ,  Clémence MÉTRO ,  Hani M. FARES

IPC: A61K8/73 ,  A61Q19/00

CPC classification number: A61K8/731 ,  A61Q19/00 ,  A61K2800/594 ,  A61K2800/74 ,  A61K2800/805

Abstract: Disclosed is an aqueous personal care composition, particularly oil-in-water, water-in-oil skin care emulsion or a suspension composition comprising 0.1 to 10 wt. % of low substituted carboxymethyl cellulose (CMC) alone or in combination with 0.01 to 10 wt. % of at least one nature derived or at least one fossil derived polymer, 0.01 to 60 wt. % of at least one personal care additive, and water; wherein, the low substituted carboxymethyl cellulose has an average degree of carboxymethyl substitution (DS) per anhydroglucose unit is in the range of from about 0.5 to about 0.7, and wherein, the low substituted carboxymethyl cellulose is readily biodegradable.

公开(公告)号：US11910724B2

公开(公告)日：2024-02-20

申请号：US16763068

申请日：2018-11-08

Applicant: ISP INVESTMENTS LLC

Inventor： Philip John Oths ,  Shafiq Sahar Wahidi ,  Petros Gebreselassie ,  Hani M. Fares

IPC: A61K8/55 ,  A61K8/73 ,  A61K8/86 ,  A61Q11/00 ,  A61K8/34 ,  H10N50/85 ,  G11C11/16 ,  G11C11/15 ,  H10B61/00 ,  H10N50/10 ,  H10N50/01 ,  H10N50/80

CPC classification number: H10N50/85 ,  A61K8/55 ,  A61K8/731 ,  A61K8/86 ,  A61Q11/00 ,  G11C11/15 ,  G11C11/161 ,  H10B61/22 ,  A61K8/345 ,  G11C11/1659 ,  H10N50/01 ,  H10N50/10 ,  H10N50/80

Abstract: A substantially anhydrous thickener system in the form of a gel for use in oral care compositions comprising: carboxymethyl cellulose or its salts thereof, a chelating agent, and hydroxyethyl cellulose, in a solvent system, wherein the thickener system is heated to a temperature ranging from about 70° C. to about 120° C. to form the gel. A method of preparing the thickener system for use in oral care compositions comprises the steps of: a) charging a mixture of hydroxyethyl cellulose and carboxymethyl cellulose into a reaction container, b) dissolving the mixture of a) in a solvent system, c) charging a chelating agent into b), and d) heating the resultant of c) to a temperature of 70°-120° C. for at least about 10 minutes.

公开(公告)号：US20240020529A1

公开(公告)日：2024-01-18

申请号：US18034149

申请日：2021-10-27

Applicant: ISP INVESTMENTS LLC

Inventor： Yunxia BI ,  Thomas DURIG ,  Solomon Howard JACOBSON

IPC: G06N3/08

CPC classification number: G06N3/08

Abstract: Present invention is directed to an artificial intelligence-based method and a system, that uses both experimental results data and molecular simulation to predict properties of amorphous solid dispersions such as glass transition temperature, dissolution profile, and/or physical stability. The method and system of the present invention enable rational design of amorphous solid dispersions for poorly water-soluble drugs and significantly reduce the time and resource required for amorphous solid dispersions formulation development.

公开(公告)号：US11766398B2

公开(公告)日：2023-09-26

申请号：US17504861

申请日：2021-10-19

Applicant: ISP INVESTMENTS LLC

Inventor： Olga Dueva-Koganov ,  Artyom Duev ,  Li Zhang ,  Karine Cucumel ,  Gilles Oberto

IPC: A61K8/9789 ,  A61Q19/08

CPC classification number: A61K8/9789 ,  A61Q19/08 ,  A61K2800/805 ,  A61K2800/81

Abstract: Disclosed herein are methods of improving skin appearance associated with skin aging. The method comprises the step of applying an anti-aging bioactive composition to a skin surface having at least one sign of aging. The anti-aging bioactive composition is applied for a period of time sufficient to improve the appearance of the at least one sign of aging. In one embodiment, the anti-aging bioactive composition comprises an effective amount of a Nelumbo nucifera (Sacred Lotus) serum fraction. In another embodiment, the anti-aging bioactive composition comprises an effective amount of a Chamomilla recutita (German Chamomile) Flower serum fraction. In other embodiments, the anti-aging bioactive composition can further include a dermatologically acceptable carrier.

公开(公告)号：US11628133B2

公开(公告)日：2023-04-18

申请号：US15565226

申请日：2016-04-08

Applicant: ISP INVESTMENTS LLC

Inventor： Nouha Domloge ,  Catherine Gondran ,  Ludivine Mur

IPC: A61K8/64 ,  A61Q19/02 ,  A61Q19/08

Abstract: The present invention relates to the cosmetic use of a composition including, as the active agent, 0.1 to 1 μM of a synthetic peptide of sequence His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 or one of the salts thereof in a physiologically suitable medium, in order to reduce or delay the appearance of cell senescence and signs of skin aging. The present invention also relates to a method for cosmetic treatment which relates to these novel uses, including comprising the steps of applying the composition, topically, at least once per day, for a period of at least two days.

公开(公告)号：US11619749B2

公开(公告)日：2023-04-04

申请号：US17257729

申请日：2019-06-28

Applicant: ISP Investments LLC

Inventor： Robert Crohn ,  David K. Hood

IPC: G01T1/06 ,  G01J1/02 ,  G01T1/08

Abstract: Provided herein is a dosimetry device for quantifying the dosage of radiation emitted from a radiation source, the device comprising: (i) a radiation dose indicator; (ii) an optical means to capture the color change; and (iii) a software means to compare the optical density of the dose indicator as compared to a predetermined calibration curve. Also provided herein is a method of quantifying the dosage of radiation emitted from the radiation source. Further provided herein is use of said dosimetry device in various medical, food and industrial applications.

公开(公告)号：US20220362141A1

公开(公告)日：2022-11-17

申请号：US17769679

申请日：2020-10-13

Applicant: ISP INVESTMENTS LLC

Inventor： Desai MAHESH ,  Robert MCCRIMLISK ,  Quyen Vo SCHWING

IPC: A61K9/46 ,  A61K9/16 ,  A61K9/20

Abstract: A dry stable effervescent co-processed excipient composition comprising: (i) about 0.1 to about 50 wt. % of one or more carbonate bases selected from the group consisting of alkali carbonate, alkali bicarbonate, alkaline earth carbonate, alkaline earth bicarbonate and mixtures thereof; (ii) about 0.1 to about 50 wt. % of a water soluble carbohydrate sugar alcohol and; (iii) about 0.001. to about 40 wt % of one or more organic acids. Also disclosed is a process for preparing the composition.