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公开(公告)号：US12065471B2
公开(公告)日：2024-08-20
申请号：US17478041
申请日：2021-09-17
发明人： Colette Song , Heiko Schuster , Daniel Johannes Kowalewski , Oliver Schoor , Jens Fritsche , Toni Weinschenk , Harpreet Singh
IPC分类号： C07K14/47 , A61K35/17 , A61K38/08 , A61K39/00 , C07K7/04 , C07K7/06 , C07K14/725 , C07K14/74 , C07K16/18 , C12N5/0783 , C12Q1/6886 , G16B25/10
CPC分类号： C07K14/4748 , A61K35/17 , A61K39/0011 , C07K14/7051 , C07K14/70539 , C07K16/18 , C12N5/0636 , C12Q1/6886 , A61K38/08 , C07K7/04 , C07K7/06 , C07K2319/00 , C07K2319/55 , C12Q2600/106 , C12Q2600/156 , C12Q2600/158 , G16B25/10
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：US11918607B2
公开(公告)日：2024-03-05
申请号：US17377724
申请日：2021-07-16
发明人： Heiko Schuster , Franziska Hoffgaard , Jens Fritsche , Oliver Schoor , Toni Weinschenk , Daniel Johannes Kowalewski , Chih-Chiang Tsou
IPC分类号： A61K39/00 , A61K35/17 , A61K38/08 , A61K39/12 , A61K39/39 , A61K39/395 , A61K45/06 , A61P35/00 , A61P35/02 , C07K7/06 , C07K14/47 , C07K14/54 , C07K16/24 , C07K16/28 , C12N5/0783 , A61K45/00
CPC分类号： A61K35/17 , A61K38/08 , A61K39/001102 , A61K39/001114 , A61K39/001118 , A61K39/12 , A61K39/39 , A61K39/39558 , A61K45/06 , A61P35/00 , A61P35/02 , C07K7/06 , C07K14/4748 , C07K14/5434 , C07K16/244 , C07K16/2818 , C07K16/2821 , C12N5/0636 , A61K2039/5154 , A61K2039/5156 , A61K2039/5158 , A61K2039/55516 , A61K2039/55533 , A61K2039/55538 , A61K2039/55561 , A61K2039/572 , A61K2039/585 , A61K45/05
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：US11629177B2
公开(公告)日：2023-04-18
申请号：US17896923
申请日：2022-08-26
发明人： Colette Song , Heiko Schuster , Daniel Johannes Kowalewski , Oliver Schoor , Jens Fritsche , Toni Weinschenk , Harpreet Singh
IPC分类号： C07K14/47 , A61K35/17 , A61K39/00 , C07K14/725 , C07K14/74 , C07K16/18 , C12N5/0783 , C12Q1/6886 , C07K7/04 , A61K38/08 , C07K7/06 , G16B25/10
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：US11576955B2
公开(公告)日：2023-02-14
申请号：US17876899
申请日：2022-07-29
发明人： Colette Song , Linus Backert , Heiko Schuster , Daniel Johannes Kowalewski , Oliver Schoor , Jens Fritsche , Toni Weinschenk , Harpreet Singh
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：US11357797B2
公开(公告)日：2022-06-14
申请号：US17478036
申请日：2021-09-17
发明人： Heiko Schuster , Franziska Hoffgaard , Jens Fritsche , Oliver Schoor , Toni Weinschenk , Daniel Johannes Kowalewski , Chih-Chiang Tsou
IPC分类号： A61K39/00 , A61K35/17 , A61P35/00 , A61K39/39 , C07K16/28 , C07K7/06 , C07K14/54 , A61P35/02 , A61K45/06 , C12N5/0783 , A61K39/12 , C07K16/24 , A61K39/395 , A61K38/08 , C07K14/47 , A61K45/00
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：US11214604B2
公开(公告)日：2022-01-04
申请号：US16413439
申请日：2019-05-15
发明人： Colette Song , Franziska Hoffgaard , Daniel Johannes Kowalewski , Oliver Schoor , Jens Fritsche , Toni Weinschenk , Harpreet Singh
IPC分类号： C07K14/47 , A61P35/02 , A61P35/00 , A61K39/00 , A61K35/17 , A61K45/06 , C07K14/725 , C07K14/74 , C07K16/28 , C07K16/30 , C12N5/0783 , C12N15/115
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：US11208448B2
公开(公告)日：2021-12-28
申请号：US16916443
申请日：2020-06-30
发明人： Colette Song , Heiko Schuster , Daniel Johannes Kowalewski , Oliver Schoor , Jens Fritsche , Toni Weinschenk , Harpreet Singh
IPC分类号： A61K35/17 , C07K14/74 , C07K7/04 , C12Q1/6886 , C07K14/47 , A61K39/00 , C07K14/725 , C07K16/18 , C12N5/0783 , G16B25/10 , A61K38/08 , C07K7/06
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：US11065279B2
公开(公告)日：2021-07-20
申请号：US17097798
申请日：2020-11-13
发明人： Heiko Schuster , Franziska Hoffgaard , Jens Fritsche , Oliver Schoor , Toni Weinschenk , Daniel Johannes Kowalewski , Chih-Chiang Tsou
IPC分类号： A61K39/00 , A61K35/17 , A61P35/00 , A61K39/39 , C07K16/28 , C07K7/06 , C07K14/54 , A61P35/02 , A61K45/06 , C12N5/0783 , A61K39/12 , C07K16/24 , A61K39/395 , A61K38/08 , C07K14/47 , A61K45/00
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：US11007223B2
公开(公告)日：2021-05-18
申请号：US16804548
申请日：2020-02-28
发明人： Juliane Sarah Walz , Daniel Johannes Kowalewski , Markus Loeffler , Moreno Di Marco , Nico Trautwein , Annika Nelde , Stefan Stevanovic , Hans-Georg Rammensee , Sebastian Haen
IPC分类号： A61K35/17 , C07K7/06 , C07K14/74 , C07K16/28 , C07K14/725 , C12N15/115 , A61P35/00 , A61K39/00 , C12N5/0783 , C07K14/47 , G01N33/50
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：US20210128708A1
公开(公告)日：2021-05-06
申请号：US17149397
申请日：2021-01-14
发明人： Colette SONG , Linus Backert , Heiko Schuster , Daniel Johannes Kowalewski , Oliver Schoor , Jens Fritsche , Toni Weinschenk , Harpreet Singh
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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