公开(公告)号：US20200325240A1

公开(公告)日：2020-10-15

申请号：US16707940

申请日：2019-12-09

申请人： ImmunoGen, Inc.

发明人： Olga AB ,  Daniel TAVARES ,  Julianto SETIADY ,  Sharron LADD ,  Christina N. CARRIGAN ,  Lingyun RUI

IPC分类号： C07K16/30 ,  G01N33/574 ,  C07K16/28 ,  A61K47/68

摘要： The invention generally relates to antibodies that bind to human folate receptor and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.

公开(公告)号：US20220143208A1

公开(公告)日：2022-05-12

申请号：US17463156

申请日：2021-08-31

申请人： ImmunoGen, Inc.

发明人： Christina N. CARRIGAN ,  Kathleen R. WHITEMAN ,  Gillian PAYNE ,  Sharron LADD

IPC分类号： A61K47/68 ,  C07K16/28 ,  G01N33/574

摘要： Methods to improve the success of cancer therapies that target the human folate receptor 1 are provided. Kits comprising reagent useful in the methods are further provided.

公开(公告)号：US20220169745A1

公开(公告)日：2022-06-02

申请号：US17523126

申请日：2021-11-10

申请人： ImmunoGen, Inc.

发明人： Olga AB ,  Daniel TAVARES ,  Julianto SETIADY ,  Sharron LADD ,  Christina N. CARRIGAN ,  Lingyun RUI

IPC分类号： C07K16/30 ,  G01N33/574 ,  C07K16/28 ,  A61K47/68

摘要： The invention generally relates to antibodies that bind to human folate receptor and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.

公开(公告)号：US20190023805A1

公开(公告)日：2019-01-24

申请号：US16002364

申请日：2018-06-07

申请人： ImmunoGen, Inc.

发明人： Olga AB ,  Daniel TAVARES ,  Julianto SETIADY ,  Sharron LADD ,  Christina N. CARRIGAN ,  Lingyun RUI

IPC分类号： C07K16/30 ,  A61K47/68 ,  G01N33/574 ,  C07K16/28 ,  A61K39/00

摘要： The invention generally relates to antibodies that bind to human folate receptor and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.

公开(公告)号：US20170306041A1

公开(公告)日：2017-10-26

申请号：US15473008

申请日：2017-03-29

申请人： ImmunoGen, Inc.

发明人： Olga AB ,  Daniel TAVARES ,  Julianto SETIADY ,  Sharron LADD ,  Christina N. CARRIGAN ,  Lingyun RUI

IPC分类号： C07K16/30 ,  G01N33/574 ,  C07K16/28 ,  A61K39/00

CPC分类号： C07K16/30 ,  A61K47/48384 ,  A61K47/48561 ,  A61K47/6803 ,  A61K47/6849 ,  A61K2039/505 ,  C07K16/28 ,  C07K2317/24 ,  C07K2317/33 ,  C07K2317/565 ,  C07K2317/92 ,  G01N33/57411 ,  G01N33/57415 ,  G01N33/57449 ,  G01N33/57492 ,  G01N2800/52

摘要： The invention generally relates to antibodies that bind to human folate receptor and diagnostic assays for folate receptor 1-based therapies. Methods of using the antibodies to monitor therapy are further provided.