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公开(公告)号:US20130289961A1
公开(公告)日:2013-10-31
申请号:US13825058
申请日:2011-09-20
申请人: Indranil Ray , Richard E. Lewis , Oliver Clinton Mullins , Colin Longfield , Bruce MacKay , Paul George , Rashmi Bhanulal Bhavsar , Chris Wilkinson
发明人: Indranil Ray , Richard E. Lewis , Oliver Clinton Mullins , Colin Longfield , Bruce MacKay , Paul George , Rashmi Bhanulal Bhavsar , Chris Wilkinson
IPC分类号: G01V9/00
摘要: Embodiments disclosed herein relate to reservoir characterization techniques and methods for accurately predicting scale tendencies of formation fluids, developed with the newly discovered phenomena that extreme downhole conditions affect the properties of reservoir fluids, including both the brine and dense hydrocarbon gas phases. In one aspect, there is disclosed a method for producing fluids from a geological formation. The method comprises inputting at least one property of a geological formation into an equation of state (EOS) model. The EOS model accounts for bound water, a high temperature effect on the brine and a high temperature effect on the dense gas phase. The EOS model is solved to determine a character of fluids contained in the geological formation, and inputting a production condition or a plurality of production conditions into the EOS model. A character of the fluids is determined based on the determined character of the fluids in the geological formation and the input production conditions. The solution can be output to a display device. Planning of the production of fluids from the geological formation can be performed. Production conditions can be controlled or adjusted.
摘要翻译: 本文公开的实施例涉及用于准确地预测地层流体的尺度倾向的储层表征技术和方法,该新技术用新发现的现象开发出极端井下条件影响储层流体的性质,包括盐水和致密烃气相。 一方面,公开了一种从地质层产生流体的方法。 该方法包括将地质构造的至少一个属性输入到状态方程(EOS)模型中。 EOS模型考虑了结合水,对盐水具有高温作用,对致密气相具有高温作用。 解决EOS模型,以确定地质构造中含有的流体特性,并将生产条件或多个生产条件输入到EOS模型中。 基于地质构造中的流体的确定特征和输入生产条件来确定流体的特征。 该解决方案可以输出到显示设备。 可以对地质地层中的流体进行规划。 生产条件可以控制或调整。
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2.
公开(公告)号:US07960409B2
公开(公告)日:2011-06-14
申请号:US12012246
申请日:2008-02-01
申请人: Erich L. Grimm , Yves Ducharme , Richard Frenette , Richard Friesen , Marc Gagnon , Helene Juteau , Sebastien Laliberte , Bruce MacKay , Yves Gareau
发明人: Erich L. Grimm , Yves Ducharme , Richard Frenette , Richard Friesen , Marc Gagnon , Helene Juteau , Sebastien Laliberte , Bruce MacKay , Yves Gareau
IPC分类号: A61K31/47 , A61K31/4192 , C07D487/04 , C07D401/06
CPC分类号: C07D401/06 , C07D401/14 , C07D405/06 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14
摘要: The instant invention provides compounds of Formula I which are leukotriene biosynthesis inhibitors. Compounds of Formula I are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.
摘要翻译: 本发明提供了作为白三烯生物合成抑制剂的式I化合物。 式I的化合物可用作抗动脉粥样硬化,抗哮喘,抗过敏,抗炎和细胞保护剂。
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公开(公告)号:US20090030048A1
公开(公告)日:2009-01-29
申请号:US12215499
申请日:2008-06-27
申请人: Marc Blouin , Erich L. Grimm , Yves Gareau , Marc Gagnon , Helene Juteau , Sebastien Laliberte , Bruce MacKay , Richard Friesen
发明人: Marc Blouin , Erich L. Grimm , Yves Gareau , Marc Gagnon , Helene Juteau , Sebastien Laliberte , Bruce MacKay , Richard Friesen
IPC分类号: A61K31/427 , A61K31/4245 , A61P11/06
CPC分类号: C07D417/14 , C07D413/12 , C07D417/12
摘要: The instant invention provides compounds of Formula Ia which are leukotriene biosynthesis inhibitors. Compounds of Formula Ia are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.
摘要翻译: 本发明提供了作为白三烯生物合成抑制剂的式Ia化合物。 式Ia的化合物可用作抗动脉粥样硬化,抗哮喘,抗过敏,抗炎和细胞保护剂。
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4.
公开(公告)号:US20140338888A1
公开(公告)日:2014-11-20
申请号:US14234587
申请日:2012-07-26
IPC分类号: C10M127/04 , E21B43/16
CPC分类号: C10M127/04 , C09K8/035 , C10M169/04 , C10M2203/06 , C10M2203/1006 , C10M2205/022 , C10M2207/2805 , C10M2207/401 , C10M2211/0225 , C10M2211/063 , C10N2230/02 , C10N2240/08 , E21B43/16 , F15B21/06
摘要: An enhanced hydraulic fluid comprises a conventional hydraulic fluid in combination with a predetermined amount of benzene by volume relative to the conventional hydraulic fluid. The predetermined amount of benzene preferably comprises between about 1.0% to about 20.0% benzene by volume, more preferably between about 1.5% to about 10.0% benzene by volume, and most preferably between about 2.0% to about 5.0% benzene by volume. The conventional hydraulic fluid may comprise electronics coolant liquids and oils. Conventional hydraulic fluids that may be mixed with benzene in the volumes described above include, but are not limited to, FLUORINERTS™ that include FC-43 and FC-70, including any perfluorinated, partially fluorinated, or partially chlorinated alkane with between about 3 to about 18 carbon atoms; mineral oils that include CAPELLA™ brand mineral oil; esther oils (synthetic or natural) that include formidals, and MIDEL™ brand esther oils.
摘要翻译: 增强的液压流体包括常规液压流体与预定量的苯相对于常规液压流体的体积的组合。 苯的预定量优选为苯体积的约1.0%至约20.0%,更优选苯体积的约1.5%至约10.0%,最优选苯体积的约2.0%至约5.0%。 传统的液压流体可以包括电子冷却剂液体和油。 可以与上述体积的苯混合的常规液压流体包括但不限于包含FC-43和FC-70的FLUORINER TM TM,包括任何全氟化,部分氟化或部分氯化的烷烃,其中约3至 约18个碳原子; 矿物油,包括CAPELLA™品牌矿物油; 含有甲醛的天然油(合成或天然油)和MIDEL™品牌esther油。
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公开(公告)号:US20090227638A1
公开(公告)日:2009-09-10
申请号:US11886757
申请日:2006-03-21
申请人: Marc Blouin , Erich L. Grimm , Yves Gareau , Marc Gagnon , Helene Juteau , Sebastien Laliberte , Bruce MacKay , Richard Friesen
发明人: Marc Blouin , Erich L. Grimm , Yves Gareau , Marc Gagnon , Helene Juteau , Sebastien Laliberte , Bruce MacKay , Richard Friesen
IPC分类号: A61K31/433 , C07D417/12 , A61K31/4245 , C07D417/14 , A61P9/10
CPC分类号: C07D417/14 , C07D413/12 , C07D417/12
摘要: The instant invention provides compounds of Formula (Ia) which are leukotriene biosynthesis inhibitors, wherein X is O or S, Y is O, S, —NR6—CHR7— or —NR8—C(O)— and A is selected from 5-membered aromatic heterocyclic ring, 6-membered aromatic heterocyclic ring, naphthelenic or heterobicyclic aromatic ring system, phenyl and benzyl. A is optionally mono- or disubstituted. Compounds of Formula (Ia) are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.
摘要翻译: 本发明提供了作为白三烯生物合成抑制剂的式(Ia)化合物,其中X是O或S,Y是O,S,-NR 6 -CHR 7 - 或-NR 8 -C(O) - ,A选自5- 苯并苯基和苄基。 A任选被单取代或二取代。 式(Ia)的化合物可用作抗动脉粥样硬化,抗哮喘,抗过敏,抗炎和细胞保护剂。
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公开(公告)号:US07553973B2
公开(公告)日:2009-06-30
申请号:US11385615
申请日:2006-03-21
申请人: Marc Blouin , Erich L. Grimm , Yves Gareau , Marc Gagnon , Helene Juteau , Sebastien Laliberte , Bruce MacKay , Richard Friesen
发明人: Marc Blouin , Erich L. Grimm , Yves Gareau , Marc Gagnon , Helene Juteau , Sebastien Laliberte , Bruce MacKay , Richard Friesen
IPC分类号: A01N43/82 , C07D285/08 , C07D271/06
CPC分类号: C07D417/14 , C07D413/12 , C07D417/12
摘要: The instant invention provides compounds of Formula Ia which are leukotriene biosynthesis inhibitors. Compounds of Formula Ia are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.
摘要翻译: 本发明提供了作为白三烯生物合成抑制剂的式Ia化合物。 式Ia的化合物可用作抗动脉粥样硬化,抗哮喘,抗过敏,抗炎和细胞保护剂。
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公开(公告)号:US10066185B2
公开(公告)日:2018-09-04
申请号:US14234587
申请日:2012-07-26
IPC分类号: E21B36/00 , C10M127/04 , F15B21/06 , C10M169/04 , C09K8/035 , E21B43/16
摘要: An enhanced hydraulic fluid comprises a conventional hydraulic fluid in combination with a predetermined amount of benzene by volume relative to the conventional hydraulic fluid. The predetermined amount of benzene preferably comprises between about 1.0% to about 20.0% benzene by volume, more preferably between about 1.5% to about 10.0% benzene by volume, and most preferably between about 2.0% to about 5.0% benzene by volume. The conventional hydraulic fluid may comprise electronics coolant liquids and oils. Conventional hydraulic fluids that may be mixed with benzene in the volumes described above include, but are not limited to, FLUORINERTS™ that include FC-43 and FC-70, including any perfluorinated, partially fluorinated, or partially chlorinated alkane with between about 3 to about 18 carbon atoms; mineral oils that include CAPELLA™ brand mineral oil; esther oils (synthetic or natural) that include formidals, and MIDEL™ brand esther oils.
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公开(公告)号:US20100249163A1
公开(公告)日:2010-09-30
申请号:US12746037
申请日:2008-11-26
申请人: Daniel Dube , Erich L. Grimm , Dwight MacDonald , Bruce MacKay
发明人: Daniel Dube , Erich L. Grimm , Dwight MacDonald , Bruce MacKay
IPC分类号: A61K31/513 , A61K31/4545 , A61K31/454 , A61K31/451 , C07D401/04 , C07D417/04 , C07D211/52 , A61P9/10 , A61P27/06 , A61P9/04 , A61P5/42 , A61P13/12 , A61P9/12 , A61P15/10 , A61P25/22
CPC分类号: C07D211/60 , C07D401/04 , C07D401/12 , C07D409/04 , C07D413/04 , C07D417/04
摘要: The present invention relates to piperidinyl-based renin inhibitor compounds having the formula containing amino-terminal groups, and their use in treating cardiovascular events and renal insufficiency.
摘要翻译: 本发明涉及具有含有氨基末端基团的式的哌啶基肾素抑制剂化合物及其在治疗心血管事件和肾功能不全中的用途。
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公开(公告)号:US20080188521A1
公开(公告)日:2008-08-07
申请号:US12012246
申请日:2008-02-01
申请人: Erich L. Grimm , Yves Ducharme , Richard Frenette , Richard Friesen , Marc Gagnon , Helene Juteau , Sebastien Laliberte , Bruce MacKay , Yves Gareau
发明人: Erich L. Grimm , Yves Ducharme , Richard Frenette , Richard Friesen , Marc Gagnon , Helene Juteau , Sebastien Laliberte , Bruce MacKay , Yves Gareau
IPC分类号: A61K31/4709 , C07D403/08 , A61K31/4192 , A61P9/10 , A61P11/06 , A61P29/00 , C07D401/08
CPC分类号: C07D401/06 , C07D401/14 , C07D405/06 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14
摘要: The instant invention provides compounds of Formula I which are leukotriene biosynthesis inhibitors. Compounds of Formula I are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.
摘要翻译: 本发明提供了作为白三烯生物合成抑制剂的式I化合物。 式I的化合物可用作抗动脉粥样硬化,抗哮喘,抗过敏,抗炎和细胞保护剂。
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公开(公告)号:US20070149579A1
公开(公告)日:2007-06-28
申请号:US11385615
申请日:2006-03-21
申请人: Marc Blouin , Erich Grimm , Yves Gareau , Marc Gagnon , Helene Juteau , Sebastien Laliberte , Bruce MacKay , Richard Friesen
发明人: Marc Blouin , Erich Grimm , Yves Gareau , Marc Gagnon , Helene Juteau , Sebastien Laliberte , Bruce MacKay , Richard Friesen
IPC分类号: A61K31/433 , A61K31/4245 , C07D417/02 , C07D413/02
CPC分类号: C07D417/14 , C07D413/12 , C07D417/12
摘要: The instant invention provides compounds of Formula Ia which are leukotriene biosynthesis inhibitors. Compounds of Formula Ia are useful as anti-atherosclerotic, anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.
摘要翻译: 本发明提供了作为白三烯生物合成抑制剂的式Ia化合物。 式Ia的化合物可用作抗动脉粥样硬化,抗哮喘,抗过敏,抗炎和细胞保护剂。
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