Patent search ap:("Industrial Technology Research Institute") AND inv:"Chih-Wei Fu" Page 1

1.

发明公开
LIPID COMPOUND OR A DERIVATIVE THEREOF AND PHARMACEUTICAL COMPOSITION EMPLOYING THE SAME 审中-公开

公开(公告)号：US20240189243A1

公开(公告)日：2024-06-13

申请号：US18507536

申请日：2023-11-13

Applicant: Industrial Technology Research Institute

Inventor： Felice Cheng , Ping-Fu Cheng , Jenn-Tsang Hwang , Chih-Wei Fu , Ku-Feng Lin , Ya-Ling Chiu , Jheng-Sian Li , Kang-Li Wang , Siou-Han Chang , Chia-Yu Fan

IPC: A61K9/51 , A61K31/7105 , A61K31/711 , A61K47/28 , C07F9/09 , C07F9/535 , C07F9/6509 , C07F9/6512

CPC classification number: A61K9/5123 , A61K31/7105 , A61K31/711 , A61K47/28 , C07F9/091 , C07F9/535 , C07F9/650952 , C07F9/6512

Abstract: A lipid compound or a derivative thereof and a pharmaceutical composition employing the same are provided. The lipid compound has a structure represented by Formula (I):

wherein Z1, Z2, Z3 and Z4 are as disclosed in the specification.

2.

发明授权
Androgen receptor binding molecule and use thereof 有权

公开(公告)号：US12152035B2

公开(公告)日：2024-11-26

申请号：US17561055

申请日：2021-12-23

Applicant: Industrial Technology Research Institute

Inventor： Chih-Wei Fu , Hao-Hsuan Liu , Chiu-Lien Hung , Yu-Chin Lin , Tsan-Lin Hu , Chien-Chin Huang

IPC: C07D487/04 , A61P35/00 , C07D401/04 , C07D401/14 , C07D417/12 , C07D417/14

Abstract: An androgen receptor (AR) binding molecule has the structure of Formula (I) shown in the following: wherein E is CH2, G is CH, is OH, NH2, OTf or C≡C, X is CF3 or trifluoromethylphenyl, is a single bond, and Y and Z are CH2; or is absent, X is CF3, is a double bond, and Y and Z are CH.

3.

发明授权
Beta-amino acid derivative, kinase inhibitor and pharmaceutical composition containing the same, and method for performing an in vivo related application that benefits from the inhibition of a kinase 有权

公开(公告)号：US11608319B2

公开(公告)日：2023-03-21

申请号：US17117615

申请日：2020-12-10

Applicant: Industrial Technology Research Institute

Inventor： Chih-Wei Fu , Chih-Peng Liu , Yi-Hsun Chen , Chia-Mu Tu , Chiu-Lien Hung

IPC: C07D231/12 , C07D403/12 , A61P27/06

Abstract: A compound represented by Formula (I), a pharmaceutically acceptable salt or ester, hydrate, solvate or crystalline form thereof is provided: The compound represented by Formula (I) is a β-amino acid derivative, and in Formula (I) X is a single bond or O; Y is NH or C═O; Z is C═O, C═S, NH, W is C or N; A is a single bond, O, OH, OCH2, a heterocycle or N3; R1 is H or F; R2 is H, F, OH, CF3, CH2OH, CHO or R3 is H; n is 0 or 1; and m is 0 or 1.

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