公开(公告)号：US11714065B2

公开(公告)日：2023-08-01

申请号：US17013658

申请日：2020-09-07

Applicant: Industrial Technology Research Institute

Inventor： Chu-Hsuan Chen ,  Yu-Fang Yen ,  Yi-Ting Tung ,  Fen-Fei Lin ,  Yi-Yun Yuan ,  Wen-Pin Hsieh

IPC: G01N27/48 ,  G01N27/02 ,  G01N27/327 ,  G01N27/42 ,  G01N33/487 ,  G01N33/49 ,  G01R27/22

CPC classification number: G01N27/48 ,  G01N27/02 ,  G01N27/3274 ,  G01N27/42 ,  G01N33/48785 ,  G01N33/49 ,  G01R27/22

Abstract: A method of measuring hematocrit is provided. The method for measuring hematocrit includes the following steps. A test strip is provided. The test strip includes a reaction region and a pair of electrodes disposed in the reaction region. A whole blood sample is entered to the reaction region. After the whole blood sample enters the reaction region, a plurality of sets of square wave voltages are intermittently applied to the pair of electrodes based on a square wave voltammetry method to obtain a plurality of feedbacks related to hematocrit. An interval between two adjacent sets of square wave voltages ranges from 0.1 seconds to 4 seconds. A feedback of an n-th set of square wave voltages is obtained to calculate a hematocrit value of the whole blood sample and n is a positive integer greater than 1. A hematocrit value is calculated according to the feedback.

公开(公告)号：US20180120258A1

公开(公告)日：2018-05-03

申请号：US15791415

申请日：2017-10-24

Applicant: Industrial Technology Research Institute

Inventor： Chu-Hsuan Chen ,  Yu-Fang Yen ,  Yi-Ting Tung ,  Fen-Fei Lin ,  Yi-Yun Yuan ,  Wen-Pin Hsieh

IPC: G01N27/48 ,  G01N27/42 ,  G01N27/02 ,  G01R27/22

CPC classification number: G01N27/48 ,  G01N27/02 ,  G01N27/3274 ,  G01N27/42 ,  G01N33/48785 ,  G01N33/49 ,  G01R27/22

Abstract: A method of measuring hematocrit and a method of testing blood are provided. The method for measuring hematocrit includes the following steps. A test strip is provided. The test strip includes a reaction region and a pair of electrodes disposed in the reaction region. A whole blood sample is entered to the reaction region. After the whole blood sample enters the reaction region, a set of square wave voltages is applied to the pair of electrodes based on a square wave voltammetry method to obtain a feedback related to hematocrit. A difference between an initial time when the whole blood sample enters the reaction region and an initial time when the set of square wave voltage is applied ranges from 0.1 seconds to 200 seconds. A hematocrit value is calculated according to the feedback.

公开(公告)号：US09903832B2

公开(公告)日：2018-02-27

申请号：US14839345

申请日：2015-08-28

Applicant: Industrial Technology Research Institute

Inventor： Chu-Hsuan Chen ,  Yu-Fang Yen ,  Yi-Yen Yuan ,  Hui-Ju Shen ,  Fen-Fei Lin ,  Yi-Ting Tung ,  Wen-Pin Hsieh

IPC: C12Q1/00 ,  G01N27/327 ,  G01N27/48

CPC classification number: G01N27/3274 ,  G01N27/3272 ,  G01N27/48

Abstract: The present disclosure provides a method for detecting an analyte concentration. The method includes providing a test strip, which includes a first electrode set including a first reaction area, a second electrode set including a second reaction area, and a reaction reagent layer disposed on the second reaction area. The method includes providing a blood sample and bringing the blood sample into contact with the first electrode set and the second electrode set, applying a first voltage to the first electrode set by voltammetry to obtain a first response value, calculating a hematocrit value according to the first response value, applying a second voltage to the second electrode set to obtain a second response value, and calculating the actual value of the analyte concentration by using the hematocrit value and the second response value.