公开(公告)号：US20180318371A1

公开(公告)日：2018-11-08

申请号：US15772810

申请日：2016-11-03

Applicant: Academia Sinica ,  Industrial Technology Research Institute

Inventor： Chang-Jen HUANG ,  Rita P.-Y. CHEN ,  Yung-Feng LIAO ,  Bo-Kai WU ,  Po-Ting CHEN ,  Hui-Ping TSAI ,  Yi-Cheng CHENG ,  Cheng-Li FANG ,  Hung-Chi CHIEN ,  Tien-Soung TONG ,  Ting-Shou CHEN ,  Shu-Jiau CHIOU

IPC: A61K36/48 ,  A61P25/28 ,  A61K9/00

CPC classification number: A61K36/48 ,  A61K2236/00

Abstract: Disclosed herein is the novel use of use of a Bauhinia spp. extract, which may upregulate neprilysin, induce autophagy, protect neuron from amyloidopathy or tauopathy, and/or promote neurite outgrowth, thus the Bauhinia spp. extract of the present disclosure may be used as a dietary supplement for the prophylaxis or treatment of amyloid related neurodegenerative diseases so as to ameliorate or alleviate symptoms associated with the amyloid related neurodegenerative diseases.

公开(公告)号：US20170258865A1

公开(公告)日：2017-09-14

申请号：US15416391

申请日：2017-01-26

Applicant: Industrial Technology Research Institute

Inventor： Kuo-Kuei HUANG ,  I-Horng PAN ,  Ying-Fei TSAI ,  I-Huang LU ,  Chu-Hsun LU ,  Shu-Fang WEN ,  Zong-Keng KUO ,  Shu-Jiau CHIOU

IPC: A61K36/75 ,  A61K31/404 ,  A61K31/4015 ,  A61K31/366 ,  A61K31/37

Abstract: The present disclosure provides a pharmaceutical composition for treating or alleviating an autoimmune disease and/or complication thereof and/or nephritis, including: an effective amount of an extract of a plant belonging to Rutaceae as an effective ingredient for treating or alleviating the autoimmune disease and/or complication thereof and/or nephritis, wherein the autoimmune disease is selected from a group consisting of lupus erythematosus, psoriasis, psoriatic arthritis, ankylosing spondylitis, rheumatoid arthritis, juvenile idiopathic arthritis, Crohn's disease and ulcerative colitis (UC).

公开(公告)号：US20130287873A1

公开(公告)日：2013-10-31

申请号：US13871853

申请日：2013-04-26

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： Pei-Yi TSAI ,  Hsiang-Wen TSENG ,  Yen-Chun CHEN ,  Hui-Chun HSU ,  Yi-Hung WEN ,  Chun-Chung WANG ,  Shu-Jiau CHIOU

IPC: A61K36/185 ,  A61K36/315

CPC classification number: A61K36/185 ,  A61K36/315

Abstract: The disclosure provides a pharmaceutical composition for promoting wound healing, including an effective amount of a Sambucus plant or an Isatis plant as an active ingredient for promoting wound healing; and a pharmaceutically acceptable carrier or medium, wherein the Sambucus plant is Sambucus formosana Nakai, and the Isatis plant is Isatis indigotica Fort.

Abstract translation: 本发明提供了一种用于促进伤口愈合的药物组合物，包括有效量的接骨木植物或靛蓝植物作为促进伤口愈合的活性成分; 和药学上可接受的载体或介质，其中所述接骨木属植物是接骨木接头甲骨虫（Nucai），靛蓝植物是靛蓝靛蓝堡（Isatis indigotica Fort）。

公开(公告)号：US20210015882A1

公开(公告)日：2021-01-21

申请号：US17036985

申请日：2020-09-29

Applicant: Industrial Technology Research Institute

Inventor： Kuo-Kuei HUANG ,  I-Horng PAN ,  Ying-Fei TSAI ,  I-Huang LU ,  Chu-Hsun LU ,  Shu-Fang WEN ,  Zong-Keng KUO ,  Shu-Jiau CHIOU

IPC: A61K36/75 ,  A61K31/395 ,  A61K31/366 ,  A61K31/37 ,  A61K31/4015 ,  A61K31/404

Abstract: The present disclosure provides a pharmaceutical composition for treating or alleviating an autoimmune disease and/or complication thereof and/or nephritis, including: an effective amount of an extract of a plant belonging to Rutaceae as an effective ingredient for treating or alleviating the autoimmune disease and/or complication thereof and/or nephritis, wherein the autoimmune disease is selected from a group consisting of lupus erythematosus, psoriasis, psoriatic arthritis, ankylosing spondylitis, rheumatoid arthritis, juvenile idiopathic arthritis, Crohn's disease and ulcerative colitis (UC).

公开(公告)号：US20200246410A1

公开(公告)日：2020-08-06

申请号：US16799158

申请日：2020-02-24

Applicant: Academia Sinica ,  Industrial Technology Research Institute

Inventor： Chang-Jen HUANG ,  Rita P.-Y. CHEN ,  Yung-Feng LIAO ,  Bo-Kai WU ,  Po-Ting CHEN ,  Hui-Ping TSAI ,  Yi-Cheng CHENG ,  Cheng-Li FANG ,  Hung-Chi CHIEN ,  Tien-Soung TONG ,  Ting-Shou CHEN ,  Shu-Jiau CHIOU

IPC: A61K36/48 ,  A61P25/28 ,  A61K9/00

Abstract: Disclosed herein is the novel use of use of a Bauhinia spp. extract, which may upregulate neprilysin, induce autophagy, protect neuron from amyloidopathy or tauopathy, and/or promote neurite outgrowth, thus the Bauhinia spp. extract of the present disclosure may be used as a dietary supplement for the prophylaxis or treatment of amyloid related neurodegenerative diseases so as to ameliorate or alleviate symptoms associated with the amyloid related neurodegenerative diseases.